PROTAC ERα Degrader-13
PROTAC ERα Degrader-13 is an orally active PROTAC molecule that efficiently and selectively degrades ERα (DC50 = 3.78 nM). PROTAC ERα Degrader-13 has the characteristics of strong anti proliferation (IC50 = 0.6 nM), induction of apoptosis, and overcoming drug resistance in MCF-7 cells. PROTAC ERα Degrader-13 has good safety and no significant organ toxicity. PROTAC ERα Degrader-13 can be used for cancer research.
(Pink: ERα ligand (HY-12864); Blue: VHL ligand (HY-125845); Black: linker (HY-W040168)).
For research use only. We do not sell to patients.
- Formula: C55H61ClFN7O7S
- Molecular Weight:1018.63
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All PROTACs Isoforms
More
Biological Activity
|
ERα |
Chemical Information
-
Molecular Weight 1018.63
-
Formula C55H61ClFN7O7S
-
SMILES
CC/C(C1=CC=C(F)C=C1Cl)=C(C2=CC=C(/C=C/C(NCCOCCOCCC(N[C@H](C(N3C[C@H](O)C[C@H]3C(NCC4=CC=C(C5=C(C)N=CS5)C=C4)=O)=O)C(C)(C)C)=O)=O)C=C2)\C6=CC(C=NN7)=C7C=C6
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC ERα Degrader-13 Related Classifications
HY-178961 Related Classifications
Powered by Bioz