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Cat. No.: HY-18252B

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(R)-Avanafil

(Synonyms: (R)-TA1790)

(R)-Avanafil ((R)-TA1790) is a selective PDE5 inhibitor (IC₅₀: 5.2 nM). (R)-Avanafil can be used for research of erectile dysfunction.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 1638497-26-3
Formule: C₂₃H₂₆ClN₇O₃
Masse moléculaire:483.95

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

(R)-Avanafil Chemical Structure

CAS No.: 1638497-26-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

(R)-Avanafil ((R)-TA1790) is a selective PDE5 inhibitor (IC₅₀: 5.2 nM). (R)-Avanafil can be used for research of erectile dysfunction^[1].

IC₅₀ & Target

5.2 nM (PDE5)^[1].

Voir tous les produits spécifiques à Isoform Phosphodiesterase (PDE) :

Chemical Information

CAS No. 1638497-26-3
Masse moléculaire 483.95
Formule C₂₃H₂₆ClN₇O₃
SMILES

COC1=C(Cl)C=C(CNC2=C(C(NCC3=NC=CC=N3)=O)C=NC(N4[C@@H](CO)CCC4)=N2)C=C1
Synonyms

(R)-TA1790
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Sakamoto T, et al. The discovery of avanafil for the treatment of erectile dysfunction: a novel pyrimidine-5-carboxamide derivative as a potent and highly selective phosphodiesterase 5 inhibitor. Bioorg Med Chem Lett. 2014 Dec 1;24(23):5460-5. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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(R)-Avanafil

High-Throughput Bioactive Compound Library

Voir tous les produits spécifiques à Isoform Phosphodiesterase (PDE)

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

(R)-Avanafil Related Classifications

HY-18252B Related Classifications