SAR 97276
Based on 1 Customer Validation
SAR 97276 (Albitiazolium bromide) is an antimalarial agent. SAR 97276 interfers with the phospholipid metabolism of malarial parasites, especially the biosynthesis of phosphatidylcholine (PC). SAR 97276 enters erythrocytes through the new permeability pathways (NPP) of infected erythrocytes, and is transported into the malarial parasite by a poly-specific cation carrier.
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- Reinheit: 98.05%
- CAS. Nr.: 321915-72-4
- Formel: C24H42Br2N2O2S2
- Molecular Weight:614.54
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Jurkat | IC50 |
347 μM
Compound: T3
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Cytotoxicity against human Jurkat cells after 24 hrs by [3H]thymidine incorporation assay
Cytotoxicity against human Jurkat cells after 24 hrs by [3H]thymidine incorporation assay
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[PMID: 23289711] |
Chemical Information
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CAS. Nr. 321915-72-4
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Appearance Solid
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Molecular Weight 614.54
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Formel C24H42Br2N2O2S2
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Color Off-white to light brown
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SMILES
OCCC1=C(C)[N+](CCCCCCCCCCCC[N+]2=CSC(CCO)=C2C)=CS1.[Br-].[Br-]
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Synonyms
Albitiazolium bromide
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (162.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6272 mL | 8.1362 mL | 16.2723 mL | 40.6808 mL |
| 5 mM | 0.3254 mL | 1.6272 mL | 3.2545 mL | 8.1362 mL | |
| 10 mM | 0.1627 mL | 0.8136 mL | 1.6272 mL | 4.0681 mL | |
| 15 mM | 0.1085 mL | 0.5424 mL | 1.0848 mL | 2.7121 mL | |
| 20 mM | 0.0814 mL | 0.4068 mL | 0.8136 mL | 2.0340 mL | |
| 25 mM | 0.0651 mL | 0.3254 mL | 0.6509 mL | 1.6272 mL | |
| 30 mM | 0.0542 mL | 0.2712 mL | 0.5424 mL | 1.3560 mL | |
| 40 mM | 0.0407 mL | 0.2034 mL | 0.4068 mL | 1.0170 mL | |
| 50 mM | 0.0325 mL | 0.1627 mL | 0.3254 mL | 0.8136 mL | |
| 60 mM | 0.0271 mL | 0.1356 mL | 0.2712 mL | 0.6780 mL | |
| 80 mM | 0.0203 mL | 0.1017 mL | 0.2034 mL | 0.5085 mL | |
| 100 mM | 0.0163 mL | 0.0814 mL | 0.1627 mL | 0.4068 mL |
SAR 97276 Related Classifications
HY-14830 Related Classifications
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