1. Anti-infection
  2. Parasite
  3. Sarolaner

Sarolaner (Synonyms: PF-6450567)

Cat. No.: HY-16730 Purity: 99.47%
Handling Instructions

Sarolaner (PF-6450567) is an orally active, broad-spectrum ectoparasiticide, has efficacy against fleas and ticks on dogs, with LC80 of 0.3 μg/mL against C. felis and an LC100 of 0.003 μg/mL against O. turicata.

For research use only. We do not sell to patients.

Sarolaner Chemical Structure

Sarolaner Chemical Structure

CAS No. : 1398609-39-6

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 192 In-stock
Estimated Time of Arrival: December 31
5 mg USD 150 In-stock
Estimated Time of Arrival: December 31
10 mg USD 250 In-stock
Estimated Time of Arrival: December 31
50 mg USD 850 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1500 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Sarolaner (PF-6450567) is an orally active, broad-spectrum ectoparasiticide, has efficacy against fleas and ticks on dogs, with LC80 of 0.3 μg/mL against C. felis and an LC100 of 0.003 μg/mL against O. turicata[1].

IC50 & Target

LC80: 0.3μg/mL (C. felis)[1]
LC100: 0.003 μg/mL (O. turicata)[1]

Storage

4°C, sealed storage, away from moisture

Solvent & Solubility
In Vitro: 

DMSO : 150 mg/mL (258.02 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7201 mL 8.6005 mL 17.2010 mL
5 mM 0.3440 mL 1.7201 mL 3.4402 mL
10 mM 0.1720 mL 0.8601 mL 1.7201 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (4.30 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (4.30 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
Molecular Weight

581.36

Formula

C₂₃H₁₈Cl₂F₄N₂O₅S

CAS No.

1398609-39-6

SMILES

O=S(CC(N1CC2(OCC3=C2C=CC(C4=NO[[email protected]](C(F)(F)F)(C5=CC(Cl)=C(F)C(Cl)=C5)C4)=C3)C1)=O)(C)=O

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Sarolaner
Cat. No.:
HY-16730
Quantity:

Sarolaner

Cat. No.: HY-16730