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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
281 Results for "
Fluorescent substrate
" in MedChemExpress (MCE) Product Catalog:
Products (281)
281 Results for "Fluorescent substrate" in MCE Product Catalog:
Cat. No.: HY-D1633
CAS No.: 126938-14-5
Cat. No.: HY-D0820A
Synonyms: Sulfo-Cyanine5-alkyne triethylamine
Research Areas:
CY5-YNE triethylamine (Sulfo-Cyanine5-alkyne triethylamine) is a class of near-infrared fluorescent dye derivatives used in research related to the labeling of proteins, peptides, nucleic acids, and nanomaterials. CY5-YNE triethylamine is a click chemistry reagent. It contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. CY5-YNE triethylamine exhibits photostable emission properties in imaging applications, enabling covalent labeling of azide-modified substrates .
Cat. No.: HY-DY1034
CAS No.: 76204-02-9
Solvent and Concentration: Sterile water: 10 mM
Cat. No.: HY-D3141
Cat. No.: HY-D3182
CAS No.: 2252329-12-5
Cat. No.: HY-110210R
CAS No.: 146616-66-2
Synonyms: BODIPY FL,SE (Standard)
Target:
Research Areas:
BODIPY-FL NHS ester (Standard) is the analytical standard of BODIPY-FL NHS ester (HY-110210). This product is intended for research and analytical applications. BODIPY FL NHS ester (BODIPY FL, SE) is a cell membranes-penatrable amine-reactive fluorescent probe. The maximum excitation/emission wavelength of the BODIPY-FL NHS ester are 502/511 nm, respectively. BODIPY-FL NHS ester has high stability and is insensitive to the polarity, pH and type of solvent, and can maintain stable fluorescence properties under different environmental conditions. BODIPY-FL NHS ester can be used for the synthesis of protease substrates, live cell imaging, protein labeling and immunoassay .
Cat. No.: HY-D3170
Cat. No.: HY-D3187
CAS No.: 2484831-02-7
Cat. No.: HY-D2738
CAS No.: 2791287-15-3
Cat. No.: HY-187338
Target:
Research Areas:
CRBN ligand-908 is a cereblon (CRBN) ligand and also a HaloTag-binding degrader. CRBN ligand-908 competes with fluorescent lenalidomide ligands for binding to full-length CRBN protein. CRBN ligand-908 contains a chlorohexyl group that covalently reacts with HaloTag fused to target proteins. CRBN ligand-908 induces degradation of HaloTag-fused FAK, endogenous MARC1, and BRD4 proteins. CRBN ligand-908 is a proteasome- and Cullin-dependent degrader. CRBN ligand-908 does not induce degradation of the novel CRBN substrates GSPT1, SALL4, or CSNK1α. CRBN ligand-908 can be used to synthesize PROTACs, such as HaloPROTAC 4 (HY-187337) .
Cat. No.: HY-182383
CAS No.: 1209002-42-5
VMY-1-101 is a fluorescent cyclin-dependent kinase (CDK) inhibitor, with an excitation of 410 nm and emission of 512 nm. VMY-1-101 competitively inhibits ATP binding to CDKs. VMY-1-101 induces G2/M cell cycle arrest in human breast cancer cells. VMY-1-101 induces modest apoptosis in human breast cancer cells. VMY-1-101 blocks proliferation of human breast cancer cells, including multidrug resistance-positive cells, and is not a substrate for p-glycoprotein. VMY-1-101 localizes to the cytoplasm of human breast cancer cells. VMY-1-101 shows increased binding to human breast cancer tissue compared to fluorophore alone. VMY-1-101 can be used for the research of breast cancer .
Cat. No.: HY-D2763
CAS No.: 890928-51-5
Cat. No.: HY-D3186
CAS No.: 2163840-29-5
Synonyms: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2
Target:
Research Areas:
Cat. No.: HY-D2745
CAS No.: 1638544-48-5
Cat. No.: HY-D2984
CAS No.: 1308789-62-9
Synonyms: SNAP-PEG-NH2
Target:
Research Areas:
BG-PEG-NH2 (SNAP-PEG-NH2) is an amino-terminal fluorescent probe building block and a precursor for site-specific labeling of SNAP-tag fusion proteins. BG-PEG-NH2 undergoes one-step coupling with activated carboxyl esters to form customized SNAP-tag substrates, which covalently bind to SNAP tags via a thioether bond formed at the Cys145 site. After coupling with a caged carboxyfluorescein, BG-PEG-NH2 forms a probe with Ex/Em = 500/524 nm following ultraviolet uncaging. Coupling of BG-PEG-NH2 with SeTau-647-NHS enables visualization of GPCR signal transduction. BG-PEG-NH2 is suitable for coupling reactions in aqueous phases or buffers, conjugation of labels, and labeling of intracellular or cell-surface proteins .
Cat. No.: HY-W048513
CAS No.: 60129-59-1
Cat. No.: HY-W354821
CAS No.: 66185-70-4
Synonyms: 4-MUD
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
