137 Results for "

chalcone

" in MedChemExpress (MCE) Product Catalog:
Products (137)

137 Results for "chalcone" in MCE Product Catalog:

Cat. No.: HY-78000
CAS No.: 1571-08-0
Synonyms: 4-Carbomethoxybenzaldehyde; 4-Carboxybenzaldehyde methyl ester; Terephthalaldehydic acid methyl ester; Methyl 4-formylbenzoate
Methyl 4-formylbenzoate (4-Carbomethoxybenzaldehyde; 4-Carboxybenzaldehyde methyl ester; Terephthalaldehydic acid methyl ester; Methyl 4-formylbenzoate) is a intermediate that can be used for the synthesis of chalcone amide α-glucosidase inhibitors .
loading...
    loading...
Cat. No.: HY-148114
CAS No.: 1485521-76-3
Target:  

Autophagy

Research Areas:  

Neurological Disease Cancer

MOPIPP is a novel indolebased chalcone, and vacuolin-1, is a non-lethal vacuoleinducing 2-propyl analog of MOMIPP (HY-119624). MOPIPP induces cellular vacuolization and increases autophagosomes numbers. MOPIPP can be used for the study of glioblastoma cells .
loading...
    loading...
Cat. No.: HY-N3057
CAS No.: 18956-15-5
Pinostrobin chalcone is a chalcone found in Boesenbergia rotunda and Alpinia mutica. Pinostrobin chalcone exhibits cytotoxicity against various cancer cells. Pinostrobin chalcone is predicted to bind to the JAK active site, forming a hydrogen bond with Asn859 and hydrophobic interactions with aromatic residues. Pinostrobin chalcone can be used in research related to breast cancer, colon cancer, cervical cancer, and epidermoid carcinoma .
loading...
    loading...
Cat. No.: HY-N3007A
CAS No.: 25515-46-2
(E)-Naringenin chalcone is an orally active anti-allergic agent. (E)-Naringenin chalcone also has antioxidant, anti-inflammatory activities. (E)-Naringenin chalcone can improve adipocyte functions. (E)-Naringenin chalcone inhibits histamine release from rat peritoneal mast cell .
loading...
    loading...
Cat. No.: HY-W002179
CAS No.: 15164-44-0
4-Iodobenzaldehyde is an aromatic halobenzaldehyde derivative and synthetic intermediate. 4-Iodobenzaldehyde is used for the synthesis of various bioactive molecules such as chalcones, heterocycles, receptor antagonists and channel blockers .
loading...
    loading...
Cat. No.: HY-N9551
CAS No.: 14917-41-0
Eriodictyol chalcone is an antioxidant that inhibits multiple key enzymes including 5-LOX (IC50=0.043 μM), aromatase/CYP19A1 (IC50=2.8 μM), PTPase 1B (IC50=1.26 μM), and COX (IC50=34 μM). Eriodictyol chalcone exhibits excellent free radical scavenging activity. Eriodictyol chalcone not only inhibits the growth of plasmodia and enhances the efficacy of Artemisinin (HY-B0094), but also reduces depression-like behaviors in animal models. Eriodictyol chalcone serves as a biosynthetic precursor for Aureusidin (HY-N9834). Eriodictyol chalcone is a potential dietary supplement and herbicide, and it can be applied to research on malaria, depression, breast cancer and other related diseases .
loading...
    loading...
Cat. No.: HY-N8786
CAS No.: 15097-74-2
2,4,4'-Trihydroxydihydrochalcone is a Chalcones product that can be isolated from the resin of Dracaena draco. .
loading...
    loading...
Cat. No.: HY-N10917
CAS No.: 688360-06-7
Xanthohumol I is a derivative of Chalcone (HY-121054) that can be isolated from Humulus lupulus L. (hops). Xanthohumol I exhibits free radical scavenging activity .
loading...
    loading...
Cat. No.: HY-N7591
CAS No.: 1393922-01-4
Millepachine is a bioactive natural chalcone from Chinese herbal medicine Millettia pachycarpa Benth, exhibits strong antitumor effects against numerous human cancer cells both in vitro and in vivo .
loading...
    loading...
Cat. No.: HY-W023983
CAS No.: 611-91-6
Target:  

Drug Derivative

Research Areas:  

Cancer

Chalcone dibromide is a useful synthon in the synthesis of a large number of bioactive molecules such as pyrazolines, hydroxy pyrazolines, isoxazoles etc. Chalcone dibromide possesses antioxidant effects against tumor cells by inhibiting superoxide production and lipid peroxidation. Chalcone dibromide can be used for cancer disease research .
loading...
    loading...
Cat. No.: HY-W749844
CAS No.: 52218-19-6
Synonyms: 2',4,4',6'-Tetrahydroxy-3-methoxychalcone; 3-Methoxy-2',4',6',4-tetrahydroxychalcone
Homoeriodictyol chalcone (2',4,4',6'-Tetrahydroxy-3-methoxychalcone; 3-Methoxy-2',4',6',4-tetrahydroxychalcone) is a non-selective antioxidant radical scavenger that neutralizes reactive oxygen species (ROS). Homoeriodictyol chalcone is promising for research of neurodegenerative diseases (e.g., Alzheimer’s), inflammatory disorders, and cancers .
loading...
    loading...
Cat. No.: HY-145104
CAS No.: 136068-43-4
Purity:  98.23%
Target:  

Drug Derivative

Research Areas:  

Others

Antioxidant agent-1 is a new chalcone derivative as a potential antioxidant agent.
loading...
    loading...
Cat. No.: HY-150156
CAS No.: 2577388-38-4
Purity:  99.52%
Target:  

Others

Research Areas:  

Inflammation/Immunology

Anti-inflammatory agent 32 is a chalcone derivative with anti-inflammatory activity. Anti-inflammatory agent 32 can be used for the research of inflammatory bowel disease .
loading...
    loading...
Cat. No.: HY-W083376A
CAS No.: 959-33-1
4-Methoxychalcone is a naturally occurring chalcone compound. 4-Methoxychalcone has antioxidant activity, anti-inflammatory activity, antitumor activity and antibacterial activity. 4-Methoxychalcone can be used to study inflammation and tumor models .
loading...
    loading...
Cat. No.: HY-W012349
CAS No.: 1214-47-7
Research Areas:  

Infection Cancer

2′-Hydroxychalcone is a hydroxyl derivative of chalcones with anticancer activities. 2'-Hydroxychalcone inhibits NF-κB pathway and induces autophagy and apoptosis in breast cancer cells . 2′-Hydroxychalcone shows a better antifungal activity against the complex Paracoccidioides spp .
loading...
    loading...
Cat. No.: HY-115550
CAS No.: 1202866-96-3
Purity:  ≥98.0%
Target:  

Parasite

Research Areas:  

Infection

Chalcone 4 hydrate is an anti-parasitic agent. Chalcone 4 hydrate inhibits the growth and proliferation of Babesia and Theileria in vitro. Chalcone 4 hydrate reduces the viability of mammalian fibroblasts and kidney cells in vitro. Chalcone 4 hydrate can be used for the research of parasitic infections .
loading...
    loading...
Cat. No.: HY-N3007R
CAS No.: 73692-50-9
Naringenin chalcone (Standard) is an analytical standard of Naringenin chalcone. This product is intended for research and analytical applications. Naringenin chalcone is an orally active intermediate in the biosynthesis of flavonols. Naringenin chalcone induces apoptosis. Naringenin chalcone inhibits the production of MCP-1 and NO. Naringenin chalcone exhibits anticancer activity against glioblastoma. Naringenin chalcone has anti-inflammatory and anti-allergic properties.
loading...
    loading...
Cat. No.: HY-16558R
CAS No.: 487-52-5
Synonyms: 2’,3,4,4’-tetrahydroxy chalcone (Standard)
Butein (Standard) is the analytical standard of Butein. This product is intended for research and analytical applications. Butein is a cAMP-specific PDE inhibitor with an IC50 of 10.4 μM for PDE4 . Butein is a specific protein tyrosine kinase inhibitor with IC50s of 16 and 65 μM for EGFR and p60c-src in HepG2 cells . Butein sensitizes HeLa cells to Cisplatin through AKT and ERK/p38 MAPK pathways by targeting FoxO3a . Butein is a SIRT1 activator (STAC).
loading...
    loading...
Cat. No.: HY-N1378R
CAS No.: 19309-14-9
Synonyms: (E)-Cardamomin (Standard); (E)-Alpinetin chalcone (Standard)
(E)-Cardamonin (Standard) is the analytical standard of (E)-Cardamonin. This product is intended for research and analytical applications. (E)-Cardamonin ((E)-Cardamomin) is a novel antagonist of hTRPA1 cation channel with an IC50 of 454 nM.
loading...
    loading...
Cat. No.: HY-128452
CAS No.: 42220-77-9
Target:  

Bacterial

Research Areas:  

Infection Inflammation/Immunology

2'-Hydroxy-2-methoxychalcone (compound 3b) is a synthetic chalcone, with antimicrobial activity .
loading...
    loading...