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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
273 Results for "
co-factor
" in MedChemExpress (MCE) Product Catalog:
Products (273)
273 Results for "co-factor" in MCE Product Catalog:
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6
6 Cited Publications
6
6 Cited Publications
5
5 Cited Publications
Cat. No.: HY-W011727
CAS No.: 853645-22-4
Synonyms: Pyridoxal phosphate hydrate
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5
5 Cited Publications
Cat. No.: HY-W011727A
CAS No.: 41468-25-1
Synonyms: Pyridoxal phosphate monohydrate
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5
5 Cited Publications
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NH-3 is an orally active, reversible thyroid hormone receptor (THR) antagonist with an IC50 of 55 nM. NH-3, a derivative of the selective thyromi-metic GC-1, inhibits binding of thyroid hormones to their receptor and that inhibits cofactor recruitment . NH-3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
3
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Phenylbutazone is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Phenylbutazone, a hepatotoxin, is a nonsteroidal anti-inflammatory agent (NSAID). Phenylbutazone induces muscle blind-like protein 1 (MBNL1) expression and has the potential for ankylosing spondylitis research .
3
3 Cited Publications
Cat. No.: HY-A0124A
CAS No.: 69056-38-8
Synonyms: (6R)-BH4 dihydrochloride; (6R)-Tetrahydro-L-biopterin dihydrochloride
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3
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2
2 Cited Publications
Synonyms: 5,10-Methylenetetrafolate; ANX-510 free acid
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2
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N3PT (N3-pyridyl thiamine) is a potent and selective transketolase inhibitor. N3PT is pyrophosphorylated and then binds to transketolase with an Kd value of 22 nM (Apo-TK, transketolase lacking bound thiamine) .
2
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Nolatrexed dihydrochloride (AG 337) is an orally active and non-competitive lipophilic inhibitor of thymidylate synthase with a Ki of 11 nM for human thymidylate synthase. Nolatrexed dihydrochloride interacts at the folate cofactor binding site of the enzyme. Nolatrexed dihydrochloride increases sulfotransferases. Nolatrexed dihydrochloride induces cell cycle arrest in S phase of cancer cells. Nolatrexed dihydrochloride exhibits anticancer activity against cervical cancer.
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2 Cited Publications
Cat. No.: HY-B0152S1
CAS No.: 86967-48-8
Synonyms: Adenine-8-C13; 9H-Purin-6-amine-8-13C
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2 Cited Publications
Synonyms: Thiamine chloride hydrochloride; Vitamin B1 hydrochloride
2
2 Cited Publications
Cat. No.: HY-134757B
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Lactate Oxidase, Aerococcus viridans is a lactate oxidase derived from Aerococcus viridans. Lactate Oxidase, Aerococcus viridans uses FMN as a cofactor, catalyzes the oxidation of lactate to pyruvate via hydride transfer, and re-oxidizes reduced FMN using molecular oxygen to produce hydrogen peroxide. Lactate Oxidase, Aerococcus viridans is a flavoenzyme with important biotechnological value, which enables indirect determination of Lactate through the production of hydrogen peroxide .
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2 Cited Publications
Cat. No.: HY-P2733D
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Glycerol 3-phosphate Oxidase, Streptococcus thermophilus (EC 1.1.3.21), is an oxidoreductase that acts on the CH-OH group in donor molecules and uses oxygen as an acceptor. Glycerol 3-phosphate Oxidase participates in glycerophospholipid metabolism and utilizes a cofactor, FAD. The two substrates of Glycerol 3-phosphate Oxidase are sn-glycerol-3-phosphate and O2, while its two products are glycerophosphate and H2O2.
1
1 Cited Publications
Synonyms: coenzyme B12; cobamamide; AdoCbl
Category:
Human Gut Microbiota Metabolites Natural Products Microorganisms Metabolic Disease Endogenous metabolite Disease Research Fields
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1
Category:
Alkaloids Human Gut Microbiota Metabolites Neurological Disease Pyridine Alkaloids Endogenous metabolite Disease Research Fields
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1
1 Cited Publications
Cat. No.: HY-B2246S
CAS No.: 2687961-04-0
Synonyms: (R)-Carnitine-d9 chloride; Levocarnitine-d9 chloride
1
1 Cited Publications
TCA1 is a small molecule with activity against agent-susceptible and -resistant Mycobacterium tuberculosis (Mtb). TCA1 inhibits enzymes involved in cell wall and molybdenum cofactor biosynthesis, such as DprE1 and MoeW .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
