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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
139 Results for "
Genotoxicity
" in MedChemExpress (MCE) Product Catalog:
Products (139)
139 Results for "Genotoxicity" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-B1244S
CAS No.: 64678-69-9
Synonyms: 1,2-Dimethyl-5-nitroimidazole-d3
1
1 Cited Publications
1
1 Cited Publications
Cat. No.: HY-N4183
CAS No.: 72357-31-4
Category:
Flavonoids Flavones Phenols Polyphenols Leguminosae Extract Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer
Target:
Synonyms: Stannous chloride, 98%; Tin(II) chloride, anhydrous, 98%; Anhydrous stannous chloride, 98%
Research Areas:
Tin(II) chloride, 98% (Stannous chloride) is a biochemical reagent with genotoxicity, mutagenicity, mitotic recombinogenicity, and reactive oxygen species-inducing activity .
Cat. No.: HY-Y0481A
CAS No.: 10025-69-1
Synonyms: Stannous chloride dihydrate; Tin dichloride dihydrate
Research Areas:
Dicamba is a herbicide. Dicamba is currently used in agriculture and gardening to control the growth of different unwanted vegetable species, mainly in cereal grain crops, but also on sugar cane and soybeans, among others. Dicambais induces significant DNA damage. Dicambais induces genotoxicity and cytotoxicity.
Target:
Research Areas:
Propanedial (Malondialdehyde) (13.88 mM in water) is one of the final products of lipid peroxidation. Propanedial causes protein inactivation, DNA damage and cross-linking by forming stable covalent adducts with biological macromolecules, which is the main mechanism for its cytotoxicity and genotoxicity.
Propanedial production increases with the elevation of free radicals.
Propanedial is a key biomarker for evaluating the level of cellular oxidative stress [1][2][3].
Cat. No.: HY-B0869A
CAS No.: 125401-92-5
Research Areas:
Bispyribac sodium is a selective, orally active, systemic and post-emergence herbicide. Bispyribac sodium reduces SOD levels and inhibits ALS activity. Bispyribac sodium blocks the biosynthesis of branched-chain amino acids, resulting in growth retardation, chlorosis and necrosis of weeds. Bispyribac sodium exerts herbicidal activity against grass, sedge and broadleaf weeds in rice fields. Bispyribac sodium is hepatotoxic and genotoxic .
Cat. No.: HY-W014940
CAS No.: 97-90-5
Research Areas:
Ethylene glycol dimethacrylate is a diester formed by the condensation of Ethylene glycol (HY-Y0338) and Methacrylic acid. Ethylene glycol dimethacrylate is a cross-linking agent for polymers. Ethylene glycol dimethacrylate increases Apoptosis, GPx4, SOD2, ROS. Ethylene glycol dimethacrylate is cytotoxic and genotoxic. Ethylene glycol dimethacrylate exhibits cross-linking activity, enhancing the mechanical properties and stability of materials .
Cat. No.: HY-W043437
CAS No.: 6214-18-2
Synonyms: Isopropyl besylate
Target:
Research Areas:
Isopropyl benzenesulfonate (Isopropyl besylate) is an aromatic sulfonate compound and also a potentially genotoxic impurity .
Cat. No.: HY-151629
CAS No.: 2797066-18-1
MRV03-069 (Compound 3) is a selective colibactin-activated peptidase (ClbP) inhibitor that blocks the genotoxic effect of Colibactin (HY-145930) on eukaryotic cells. MRV03-069 can be used in colorectal cancer research .
Cat. No.: HY-W007577
CAS No.: 555-16-8
Cat. No.: HY-W012657
CAS No.: 4748-78-1
Category:
Glycine max (L.) merr Ketones, Aldehydes, Acids Metabolic Disease Leguminosae Extract Plants Endogenous metabolite Disease Research Fields
Target:
Synonyms: BIIB091
Target:
Research Areas:
Corubrutinib (BIIB091) is an orally active BTK inhibitor with an IC50 of <0.5 nM, Kd of 0.07 nM, and >500-fold kinome selectivity. Corubrutinib suppresses B cell activation, proliferation, differentiation, antibody production, antigen presentation, cytokine secretion, and myeloid cell effector functions. Corubrutinib exhibits favorable pharmacokinetic and preclinical safety profiles, including low genotoxic potential, minimal hepatotoxicity, and no major transporter or CYP inhibition. Corubrutinib can be used for the research of multiple sclerosis .
Cat. No.: HY-B1072
CAS No.: 26002-80-2
Research Areas:
Phenothrin is a Type I pyrethroid insecticide. Phenothrin induces dose-dependent DNA damage in human peripheral blood lymphocytes and hepatocytes, and exhibits definite genotoxic potential. Phenothrin acts as an insecticide for pest control in agriculture, households and public health, as well as for the elimination of human head lice infestations .
Cat. No.: HY-N8022
CAS No.: 29706-59-0
Synonyms: Lucidin 3-O-β-primeveroside
Category:
Quinones Monophenols Anthraquinones Phenols Plants Disease Research Fields Cancer Rubiaceae Extract Rubia cordifolia L.
Target:
Target:
Research Areas:
Cyanazine, a triazine herbicide cyanazine, is used to control a variety of grass weeds and broadleaf weed. Cyanazine is proved non-genotoxic .
Cat. No.: HY-N2627
CAS No.: 53584-69-3
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
