![Benzo[k]fluoranthene](https://file.medchemexpress.com/product_pic/hy-23498.gif "Click to View Benzo[k]fluoranthene Product Detail")
Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
139 Results for "
Genotoxicity
" in MedChemExpress (MCE) Product Catalog:
Products (139)
139 Results for "Genotoxicity" in MCE Product Catalog:
Target:
Research Areas:
NiCur is a potent and selective CBP histone acetyltransferase (HAT) inhibitor with an IC50 value of 0.35 μΜ. NiCur, which blocks CBP HAT activity and downregulates p53 activation upon genotoxic stress. NiCur can be used for performing mechanistic studies without affecting the expression of target proteins .
Cat. No.: HY-160596
CAS No.: 2409156-19-8
Synonyms: 5-Formyl-deoxycytidine lithium
Target:
Research Areas:
5-Formyl-dCTP (5-Formyl-deoxycytidine) lithium is a DCTPP1 substrate. 5-Formyl-dCTP lithium acts as a mutagen/epigenetic disruptor via DNA polymerase incorporation, mutagenic mispairings, and disturbed epigenetic programming. 5-Formyl-dCTP lithium can be used for research on genotoxicity .
Synonyms: FCR 2769
Flumethrin (FCR 2769) is a pyrethroid insecticide and acaricide . Flumethrin targets voltage-gated sodium channels and estrogen receptor α (ERα). Flumethrin induces cytotoxicity, apoptosis, genotoxicity and DNA damage in breast cancer cells by regulating the expression of BCL2, BAX, TP53 and P21 genes. Flumethrin is applicable to relevant studies on ectoparasite infections (tick and flea burdens) in dogs and cats, as well as breast cancer .
Target:
Research Areas:
Mequindox is an antimicrobial agent . Mequindox acts as an inhibitor of DNA synthesis. Mequindox induces genotoxicity and carcinogenicity in mice .
Cat. No.: HY-W587892
CAS No.: 7289-52-3
Synonyms: 1-Methoxydecane
Target:
Research Areas:
Decyl methyl ether is a new type of strong fatty ether. Decyl methyl ether is non-genotoxic and phototoxic/photosensitizing .
Category:
Target:
Cat. No.: HY-119635
CAS No.: 54632-04-1
Target:
Research Areas:
Benzo[k]fluoranthene is a polycyclic aromatic hydrocarbon (PAH) that is carcinogenic and genotoxic .
Cat. No.: HY-W011817
CAS No.: 21145-77-7
Synonyms: AHTN
Research Areas:
6-Acetyl-1,1,2,4,4,7-hexamethyltetraline (AHTN) is a synthetic fragrance ingredient that is not significantly genotoxic in mammalian systems .
Cat. No.: HY-400785
CAS No.: 2452300-94-4
Target:
Research Areas:
Dapagliflozin impurity A (Compound A) is a dapagliflozin peroxide, a genotoxic impurity, can cause damage to human genetic material at very low concentrations, leading to genetic mutations and possibly tumorigenesis .
Cat. No.: HY-151626
CAS No.: 2797066-16-9
MRV03-037 is a selective colibactin-activated peptidase (ClbP) inhibitor that blocks the genotoxic effect of Colibactin (HY-145930) on eukaryotic cells. MRV03-037 prevents gut bacterial genotoxin production .
Target:
Research Areas:
2,4-Dimethoxybenzaldehyde is a tumor initiator with genotoxic property. 2,4-Dimethoxybenzaldehyde can induce benign papilloma development and converse to squamous cell carcinoma in the skin of susceptible mouse models. 2,4-Dimethoxybenzaldehyde can be used for skin cancer research .
Cat. No.: HY-122817
CAS No.: 73226-73-0
Target:
Research Areas:
FR900098 sodium is an antimalarial agent that inhibits 1-deoxy-d-xylulose-5-phosphate (DXP) reductoisomerase. FR900098 sodium has no significant acute toxicity or genotoxicity, and does not have the ability to cause chromosome breakage or heterogeneity. FR900098 sodium has no effect on bone marrow red blood cells in NMRI mice .
Cat. No.: HY-N11845
CAS No.: 87746-47-2
Target:
Cat. No.: HY-114517
CAS No.: 10599-70-9
Target:
Research Areas:
3-Acetyl-2,5-dimethylfuran is a flavoring agent exhibiting genotoxic potential in vitro assays .
Cat. No.: HY-121345
CAS No.: 67910-07-0
Target:
Target:
Research Areas:
Ypenyl is a cytostatic. Ypenyl hydrochloride, belonging to the alkylating agent class, exhibits clear genotoxicity and cell cycle disruption properties. Ypenyl induces chromosomal aberrations in broad bean root tip meristem cells and leads to a decrease in the mitotic index. Ypenyl may be used in cancer research .
Cat. No.: HY-W010132
CAS No.: 94-52-0
Target:
Research Areas:
5-nitrobenzimidazole is a genotoxic nitro compound and 6-aminopurine (HY-B0152) analogue. 5-nitrobenzimidazole shows a slight inhibitory effect on xanthine oxidase, with an IC50 of 86.84 μM. 5-nitrobenzimidazole can be used in the research of hyperuricemia .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
