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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
104 Results for "
amyloid aggregation
" in MedChemExpress (MCE) Product Catalog:
Products (104)
104 Results for "amyloid aggregation" in MCE Product Catalog:
Cat. No.: HY-148495
Pureté: ≥90.0%
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Carnosine conjugated hyalyronate is a hyaluronic acid derivative functionalized with the dipeptide carnosine (Carnosine, Car) and has the ability to resist Aβ amyloid aggregation. Carnosine conjugated hyalyronate dissolves amyloid fibrils and reduces Aβ-induced toxicity in vitro. The effectiveness of Carnosine conjugated hyalyronate against amyloid aggregation is directly proportional to the Carnosine loading .
Cat. No.: HY-P1378
CAS No.: 134500-80-4
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Cat. No.: HY-P4886A
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Cat. No.: HY-117710B
CAS No.: 1531586-64-7
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AD-35 is an orally active, blood-brain barrier-permeable acetylcholinesterase inhibitor with an IC50 of 793 nM. AD-35 inhibits metal-induced amyloid-β aggregation and disassembles preformed amyloid-β aggregates. In rat models of cognitive impairment, AD-35 attenuates Aβ25-35-induced astrocyte activation, TNF-α and IL-1β release, inhibits ERK phosphorylation, and alleviates learning and memory deficits. AD-35 can be used for research on Alzheimer's disease .
Cat. No.: HY-177854
CAS No.: 603113-07-1
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Aβ aggregation-IN-4 can alleviate the neurotoxicity of amyloid-β protein (Aβ) and significantly reduce the level of oligomeric complexes of Aβ (Aβ-OCs). Aβ aggregation-IN-4 does not decrease the level of amyloid-β protein (Aβ). Aβ aggregation-IN-4 attenuates Aβ oligomerization and prevents oligomer-induced death of primary cortical neurons. Aβ aggregation-IN-4 can be used for the study of Alzheimer’s disease (AD) .
Cat. No.: HY-P3846
CAS No.: 1802086-22-1
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Cat. No.: HY-P1051
CAS No.: 107015-83-8
Synonyms: amyloid β-Protein (12-28)
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Cat. No.: HY-P5968A
Synonyms: β(25-35)KA TFA
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Cat. No.: HY-P1388F
Synonyms: FITC-Ahx-amyloid β-peptide (1-42) (rat/mouse) tris
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Cat. No.: HY-134894A
CAS No.: 883288-78-6
Synonyms: GroPEtn sodium
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Glycerophosphorylethanolamine (GroPEtn) sodium is an active phosphodiester metabolite of Phosphatidylethanolamine. Glycerophosphorylethanolamine sodium promotes the aggregation of amyloid β-protein (Aβ (1-40)) in vitro. Glycerophosphorylethanolamine sodium can be used in the field of neurodegenerative diseases, such as Alzheimer’s disease research .
Cat. No.: HY-P4886
CAS No.: 157884-74-7
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Cat. No.: HY-N2898
CAS No.: 96917-26-9
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Cat. No.: HY-179167
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K2V-9 is an AChE and MAO-B inhibitor with IC50 values of 1.72 μM and 0.950 μM against AChE and MAO-B, respectively. K2V-9 inhibits amyloid β self-aggregation and reduces ROS. K2V-9 has neuroprotective effects .
Cat. No.: HY-B1588S
Cat. No.: HY-146142
CAS No.: 1946008-31-6
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AChE/BuChE-IN-2 (Compound 5f) is an orally active AChE and BuChE inhibitor with IC50 values of 0.72 μM and 0.16 μM, respectively. AChE/BuChE-IN-2 shows a non-competitive inhibition with AChE and shows potent self-induced β-amyloid (Aβ) aggregation inhibition with an IC50 of 62.52 μM. AChE/BuChE-IN-2 can cross the BBB .
Cat. No.: HY-N15572
CAS No.: 84297-49-4
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Anti-amyloid agent-1 (ex1140) is a potent anti-amyloid compound and inhibits amyloid aggregation, provides a useful method for amyloidosis research .
Cat. No.: HY-P10037
CAS No.: 131580-11-5
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Cat. No.: HY-147820
CAS No.: 2559709-99-6
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AY1511 is an amyloid β (Aβ) aggregation inhibitor with low cytotoxicity .
Cat. No.: HY-153431
CAS No.: 1569645-63-1
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TRV-1387 is a benzofurazan that inhibits the aggregation of tau and amyloid-β .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
