614 Results for "

therapy

" in MedChemExpress (MCE) Product Catalog:
Products (614)

614 Results for "therapy" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-16477
CAS No.: 220201-34-3
Synonyms: ME2906; Mono-L-aspartyl chlorin e6; NPe6
Target:  

Photosensitizer

Research Areas:  

Cancer

Talaporfin (ME2906) sodium is a chlorin based photosensitizer. Talaporfin sodium can be used for the research of various cancers by using photodynamic therapy (PDT) .
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5
5 Cited Publications
Cat. No.: HY-W018772
CAS No.: 50-69-1
D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner .
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5
5 Cited Publications
Cat. No.: HY-B0319
CAS No.: 65899-73-2
Synonyms: UK-20349
Research Areas:  

Infection Cancer

Tioconazole (UK-20349) is a broad-spectrum antifungal imidazole derivative. Tioconazole inhibits several dermatophytes and yeasts, with MIC50 values of less than 3.12 mg/L and 9 mg/L, respectively. Additionally, Tioconazole exhibits anti-parasitic activity. Tioconazole exerts anticancer activity by inhibiting the PI3K/AKT/mTOR signaling pathway and blocking autophagy. Tioconazole is applicable for research in the fields of anti-infection and anticancer therapy .
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4
4 Cited Publications
Cat. No.: HY-128973
CAS No.: 24533-72-0
Purity:  ≥98.0%
Research Areas:  

Cancer

Pyropheophorbide-a (Ppa) is a photosensitizer used in photodynamic therapy (PDT) for tumors. Pyropheophorbide-a exhibits phototoxic effects on tumor cells, such as cervical cancer cells, and also has anti-lipogenesis activity. Pyropheophorbide-a shows potential for research in the fields of cancer and age-related macular degeneration (AMD). Pyropheophorbide-a derivatives also demonstrate inhibitory activity against tumor cells .
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3
3 Cited Publications
Cat. No.: HY-13722
CAS No.: 149402-51-7
Purity:  99.74%
Synonyms: Photochlor
Research Areas:  

Cancer

HPPH (Photochlor) is a second generation photosensitizer, which acts as a photodynamic therapy (PDT) agent.
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3
3 Cited Publications
Cat. No.: HY-18954
CAS No.: 1262417-51-5
Target:  

PARP

Research Areas:  

Cancer

NMS-P118 is a potent, orally available, and highly selective PARP-1 Inhibitor for cancer therapy.
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3
3 Cited Publications
Cat. No.: HY-12964
CAS No.: 1239875-86-5
Purity:  99.32%
Target:  

TAM Receptor

Research Areas:  

Cancer

SGI-7079 is a selective, ATP-competitive, orally active inhibitor of the receptor tyrosine kinase Axl. SGI-7079 blocks Axl-mediated signaling pathways such as NF-κB activation and MMP-9 expression, thereby inhibiting tumor cell proliferation, migration and invasion. SGI-7079 is mainly used in the research of malignant tumors such as inflammatory breast cancer and bladder cancer, as well as in combination with immunization (used in combination with PD-1 therapy)[1][2][3].
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3
3 Cited Publications
Cat. No.: HY-130492
CAS No.: 1973403-00-7
Purity:  99.88%
Research Areas:  

Cancer

ARCC-4 is a low-nanomolar Androgen Receptor (AR) degrader based on PROTAC, with a DC50 of 5?nM. ARCC-4 is an enzalutamide-based von Hippel-Lindau (VHL)-recruiting AR PROTAC and outperforms enzalutamide. ARCC-4 effectively degrades clinically relevant AR mutants associated with antiandrogen therapy .
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3
3 Cited Publications
Cat. No.: HY-P99575
CAS No.: 2307488-83-9
Synonyms: AMG-757

Target:  

Notch

Research Areas:  

Inflammation/Immunology Cancer

Tarlatamab (AMG-757) is a bispecific T-cell engager (BiTE) antibody targeting delta-like ligand 3 (DLL3). DLL3 is a target that is selectively expressed in small-cell lung cancer (SCLC) tumors, but with minimal normal tissue expression. Tarlatamab has the KDs of 0.64 nM and 0.50 nM for human and nonhuman primate (NHP) DLL3, respectively. Tarlatamab has the KDs of 14.9 nM and 12 nM for human and NHP CD3, respectively. Tarlatamab is a first-in-class HLE BiTE immuno-oncology therapy targeting DLL3 and has the potential for SCLC research .
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2
2 Cited Publications
Cat. No.: HY-N6647
CAS No.: 20633-84-5
Luteolin-7-rutinoside has both anti-arthritic and antifungal activities, can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection.
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2
2 Cited Publications
Cat. No.: HY-14925
CAS No.: 189059-71-0
Purity:  99.81%
Synonyms: T-91485
Lapaquistat (T-91485), a cholesterol biosynthesis inhibitor, is the active metabolite of Lapaquistat acetate (HY-16274). Lapaquistat can decrease statin-induced myotoxicity in lipid-lowering therapy .
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2
2 Cited Publications
Cat. No.: HY-128972
CAS No.: 25465-77-4
Purity:  ≥95.0%
Research Areas:  

Others

Purpurin 18, a derivative of chlorophyll and a type of dihydroporphyrin, is used to produce photosensitizers. Purpurin 18 photodynamic therapy can induce cell apoptosis and has anti-tumor activity .
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2
2 Cited Publications
Cat. No.: HY-137473
CAS No.: 6453-67-4
Purity:  99.14%
Synonyms: Pyropheophorbide-a methyl ester
Target:  

Apoptosis

Research Areas:  

Cancer

Methyl pyropheophorbide-a (Pyropheophorbide-a methyl ester), a chlorophyll-a derivative, is a potent photosensitizer that can be used in photodynamic therapy (PDT) of cancer. Methyl pyropheophorbide-a has photodynamic activity and can induce apoptosis and inhibit tumor growth .
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2
2 Cited Publications
Cat. No.: HY-113011
CAS No.: 1109-28-0
Purity:  ≥98.0%
Maltotriose is a maltooligosaccharide and a specific inducer of the Escherichia coli maltose operon. The oligosaccharide structure of Maltotriose acts as a highly efficient drug delivery carrier, which significantly enhances the targeting ability and water solubility of photosensitizers in photodynamic therapy for pancreatic cancer .
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2
2 Cited Publications
Cat. No.: HY-B0459
CAS No.: 498-45-3
Synonyms: 6,7-Epoxytropine
Scopine is a metabolite of Scopolamine (HY-N0296) and brain-targeting compound. Scopine significantly increases the brain exposure of Chlorambucil (HY-13593) and enhances its anti-glioma activity. Scopine can be used in targeted therapy research for brain gliomas .
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2
2 Cited Publications
Cat. No.: HY-B0459A
CAS No.: 85700-55-6
Synonyms: 6,7-Epoxytropine hydrochloride
Target:  

Drug Metabolite

Research Areas:  

Neurological Disease Cancer

Scopine hydrochloride is a metabolite of Scopolamine (HY-N0296) and brain-targeting compound. Scopine hydrochloride significantly increases the brain exposure of Chlorambucil (HY-13593) and enhances its anti-glioma activity. Scopine hydrochloride can be used in targeted therapy research for brain gliomas .
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2
2 Cited Publications
Cat. No.: HY-10182G
CAS No.: 252917-06-9
Synonyms: CHIR-99021 (GMP); CT99021 (GMP)
Laduviglusib (CHIR-99021) (GMP) is Laduviglusib (HY-10182) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Laduviglusib is a potent, orally active and selective GSK-3α/β inhibitor.
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2
2 Cited Publications
Cat. No.: HY-N2575
CAS No.: 77029-83-5
Hypocrellin A is a PKC inhibitor that exerts antidiabetic activity by reversing the effects of high glucose on endothelin (ET-1) expression. Hypocrellin A is also a photosensitizer for photodynamic therapy (PDT) with anticancer, antibacterial and antiviral activities, especially against human immunodeficiency virus (HIV). In addition, Hypocrellin-A also possesses anti-Leishmania activity (IC50=0.27 μg/ml) .
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2
2 Cited Publications
Cat. No.: HY-W073524
CAS No.: 1420815-55-9
DFAME is a red fluorophore (Ex = 508 nm, Em = 641 nm). DFAME binds to Beetroot and Corn (dimeric fluorescent RNA aptamers) to form Beetroot-DFAME (Kd = 460 nM) and Corn-DFAME (Kd = 3600 nM). Beetroot-DFAME and Corn-DFAME can be used to form RNA assemblies in living cells. Creating RNA assemblies can be used for the study of RNA Nanostructures. DNA/RNA Nanostructures would be useful in cell and gene therapy (CGT) research .
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2
2 Cited Publications
Cat. No.: HY-N0235
CAS No.: 10309-37-2
Synonyms: (S)-(+)-Bakuchiol
Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 (UGT2B7) and human carboxylesterase 2 (hCE2) , with IC50s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory , antibacterial , antitumor therapies, as well as drug metabolism regulation.
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