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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
507 Results for "
hydroxyl
" in MedChemExpress (MCE) Product Catalog:
Products (507)
507 Results for "hydroxyl" in MCE Product Catalog:
Cat. No.: HY-W271506
CAS No.: 10135-38-3
Synonyms: 3,3,5,5-Tetramethyl-1-pyrroline 1-oxide
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TMPO (3,3,5,5-Tetramethyl-1-pyrroline 1-oxide) is a spin trap targeting free radicals. TMPO is capable of scavenging superoxide, hydroxyl radicals and inhibits thymocyte apoptosis with EC50 values of 19.1 mM (MPS-induced) to 30.7 mM (Etoposide-induced) for inhibiting DNA fragmentation. TMPO reacts with intracellular free radicals to form stable nitroxide radical products, reducing oxidative stress (e.g., decreasing peroxide levels, maintaining glutathione content) and blocking oxidative events in the apoptotic pathway. TMPO is promising for research of apoptosis in immune cells like thymocytes .
Cat. No.: HY-149727
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β2AR agonist 2(compound 8a) is a β2 -Adrenergic receptor (β2AR) agonist. β2AR agonist 2 is a saturated nitrogen ring compound containing 4- to 7-membered heterocycle. β2AR agonist 2 has a chiral structure (the -R form) by carrying carbon containing the essential hydroxyl, thereby enhancing cellular glucose uptake (GU) activity and significantly stimulating glucose uptake by skeletal muscle cells. β2AR agonist 2 can be used in the study of Type 2 Diabetes (T2D) .
Cat. No.: HY-W013222
CAS No.: 55066-53-0
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(R,Z)-Ethyl 12-hydroxyoctadec-9-enoate is a naturally occurring organic compound belonging to the class of fatty acid esters. It is derived from oleic acid, a common unsaturated fatty acid found in various animal and plant sources. (R,Z)-Ethyl 12-hydroxyoctadec-9-enoate contains an ethyl group and a hydroxyl group at specific positions in the fatty acid chain. It has various applications in industry and biomedicine, especially as a precursor for the synthesis of other bioactive compounds. (R,Z)-Ethyl 12-hydroxyoctadec-9-enoate is also used in the formulation of certain types of cosmetic and personal care products, such as skin creams and lotions.
Cat. No.: HY-W015788R
CAS No.: 93-56-1
Synonyms: Styrene Glycol (Standard)
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Cat. No.: HY-W021265
CAS No.: 6917-35-7
Synonyms: Cyclohexane-1,2,3,4,5,6-hexol
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Cat. No.: HY-W243460
CAS No.: 39208-15-6
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EDTA copper (II) disodium salt, 97% is a negatively charged copper (II)-ethylenediaminetetraacetic acid chelate and also an adsorption substrate. EDTA copper (II) disodium salt, 97% forms amide bonds with chitosan amino groups in weakly acidic (pH 3-5) solutions, while it forms the CuEDTA (OH) 3− hydroxyl complex in strongly alkaline (pH > 12) solutions. EDTA copper (II) disodium salt, 97% can be adsorbed onto granular activated carbon, with electrostatic interactions dominating its pH-dependent adsorption behavior. EDTA copper (II) disodium salt, 97% can be used to eliminate the inhibition of enzyme-catalyzed reactions caused by trace heavy metals .
Cat. No.: HY-W587772
CAS No.: 1684398-38-6
Synonyms: MEHHTP
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Mono (2-ethyl-5-hydroxyhexyl) terephthalate (MEHHTP), a hydroxyl metabolite of the phthalate alternative Di-2-ethylhexyl terephthalate (DEHTP), is a liver X receptor α (LXRα) agonist with a binding energy of -7.41 kcal/mol. Mono (2-ethyl-5-hydroxyhexyl) terephthalate upregulates LXRα downstream targets such as SREBP-1c and FASN and increases lipogenic enzyme activity in hepatocytes, and elevating triglyceride (TG) levels. Mono (2-ethyl-5-hydroxyhexyl) terephthalate is promising for research of nonalcoholic fatty liver disease (NAFLD) .
Cat. No.: HY-N15727
CAS No.: 1251459-63-8
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Cat. No.: HY-119417A
CAS No.: 1954-81-0
Chloramben sodium is a herbicide with anti-growth activity against plants. Chloramben sodium can be effectively removed by photo-Fenton reaction under natural pH conditions, showing good degradation performance. The removal rate of chloramben sodium is consistent with different electrodes, mainly due to the oxidation mediated by the hydroxyl ions formed in the Fenton reaction. Chloramben sodium is almost completely mineralized using IrO2-based electrodes at high current density, indicating that it can be effectively degraded under light. Chloramben sodium leads to the formation of persistent chlorine derivatives in chlorine-containing environments, so the removal rate and mineralization rate are slightly reduced. Chloramben sodium can form intermediates with a variety of aromatic compounds and organic acids, reflecting the complexity of its transformation in the environment .
Dieugenol is a neolignan that has been found in N. leucantha and has antioxidative and antiprotozoal activities. It inhibits the formation of thiobarbituric acid reactive substances (TBARS) and scavenges superoxide anions, but not hydroxyl radicals, in cell-free assays. It has anti-trypanosomal activity against T. cruzi amastigotes and trypomastigotes (IC50s=15.1 and 11.5 μM, respectively) but is cytotoxic to NCTC L-929 fibroblasts with a 50% cytotoxic concentration (CC50) value of 58.2 μM.2 Dieugenol (15 μM) disrupts the integrity of the T. cruzi trypomastigote plasma membrane but does not induce the production of reactive oxygen species (ROS) in trypomastigotes or LPS-stimulated and unstimulated isolated mouse peritoneal macrophages.
Synonyms: N-Acetyl-L-serine
Galactinol dihydrate is a disaccharide carbohydrate serving as a galactosyl donor, which belongs to the raffinose family oligosaccharide pathway and acts as an important osmoprotectant. Galactinol dihydrate not only induces disease resistance in plants against fungal and bacterial pathogens, but also significantly enhances plant tolerance to abiotic stresses such as drought, high salinity, low temperature and oxidative damage. In addition, Galactinol dihydrate has the ability to scavenge hydroxyl radicals, can act as a signaling component for root colonization-induced systemic resistance, and is positively correlated with seed longevity in various crops, making it a potential biomarker for evaluating seed vigor. Therefore, Galactinol dihydrate can be used in the research of various plant diseases including fungal leaf spot, bacterial angular leaf spot, gray mold and soft rot .
Cat. No.: HY-149151
CAS No.: 20988-30-1
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Cat. No.: HY-183549
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Ferroptosis/apoptosis inducer-4 is a pyridine-hydrazone-derived Cu (II) complex and a synergistic inducer of ferroptosis and apoptosis. Ferroptosis/apoptosis inducer-4 exerts anti-tumor proliferation and anti-metastasis effects with extremely low systemic toxicity. Ferroptosis/apoptosis inducer-4 disrupts cellular redox homeostasis by depleting glutathione and generating hydroxyl radicals through the Cu 2+/Cu + redox cycle. Ferroptosis/apoptosis inducer-4 also triggers mitochondrial dysfunction and endoplasmic reticulum stress, which in turn lead to Ca 2+ release, mitochondrial Ca 2+ overload, and the formation of a ROS−Ca 2+ self-amplifying feedback loop. Ferroptosis/apoptosis inducer-4 can be used in studies related to cervical cancer .
Cat. No.: HY-189150
CAS No.: 1643925-08-9
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NSP-116 is an orally active antioxidant and neuroprotective agent. NSP-116 protects corneal epithelial cells from UV-A and blue light LED-induced photo-oxidative damage. NSP-116 scavenges DPPH, superoxide anion, and hydroxyl radicals, inhibits light-induced ROS production in photoreceptor cells, and inhibits lipid peroxidation in retinal homogenates. NSP-116 prevents light-induced photoreceptor cell death and retinal degeneration, and inhibits intracellular Fe 2+ accumulation, autophagy, apoptosis, p38 phosphorylation, and microglial/macrophage activation. NSP-116 exerts neuroprotective effects in hemorrhagic stroke models. NSP-116 can be used for research on photokeratitis, dry age-related macular degeneration, and intracranial hemorrhage .
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Clove oil (Clove leaf oil,rectified) is a volatile aromatic essential oil with antibacterial, anti-inflammatory and antioxidant activities. Clove oil disrupts the integrity of bacterial cell membranes, releases intracellular nucleic acids and proteins, and inhibits bacterial growth and reproduction. Clove oil scavenges DPPH, ABTS, superoxide anions, hydrogen peroxide and hydroxyl radicals. Clove oil reduces Fe 3+ to Fe 2+, chelates Fe 2+ and iron ions, and inhibits lipid peroxidation in linoleic acid emulsions. Clove oil acts as a natural preservative to reduce the loss of oxidation products. Clove oil can be isolated from the flowers, stems and leaves of Eugenia aromatica and Eugenia caryophyllus, which belong to the Myrtaceae family. Clove oil can be used in studies related to bacterial infection, antioxidation and preservation .
Cat. No.: HY-N21668
CAS No.: 114297-65-3
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Cat. No.: HY-N3847
CAS No.: 38965-51-4
Synonyms: Eriodictyol 7-O-β-D-glucoside
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Flavonoids Flavonones Metabolic Disease Phenols Polyphenols Plants Disease Research Fields Petalostemun purpureum Labiatae Extract
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
