311 Results for "

Tryptophan

" in MedChemExpress (MCE) Product Catalog:
Products (311)

311 Results for "Tryptophan" in MCE Product Catalog:

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1 Cited Publications
Cat. No.: HY-23460
CAS No.: 278605-15-5
Synonyms: 4-Ethynyl-L-phenylalanine
Research Areas:  

Neurological Disease

p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine) is a potent, selective, reversible and competitive inhibitor of tryptophan hydroxylase (TPH), with a Ki of 32.6 μM . p-Ethynylphenylalanine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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1 Cited Publications
Cat. No.: HY-23460A
CAS No.: 188640-63-3
Synonyms: 4-Ethynyl-L-phenylalanine hydrochloride
Research Areas:  

Neurological Disease

p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine hydrochloride) is a potent, selective, reversible and competitive inhibitor of tryptophan hydroxylase (TPH), with a Ki of 32.6 μM . p-Ethynylphenylalanine (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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1 Cited Publications
Cat. No.: HY-W015273A
CAS No.: 29953-71-7
Trans-3-Indoleacrylic acid is a tryptophan metabolite, which promotes tumor development through inhibition of RSL3 (HY-100218A) induced ferroptosis via AHR-ALDH1A3-FSP1-CoQ10 axis, and facilitates colorectal carcinogenesis
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1 Cited Publications
Cat. No.: HY-151223
CAS No.: 591-57-1
Purity:  99.84%
Synonyms: Triose phosphate
D-Glyceraldehyde 3-phosphate (Triose phosphate) is a key intermediate in glycolysis and gluconeogenesis, as well as a carbohydrate product of the Calvin cycle. D-Glyceraldehyde 3-phosphate participates in the biosynthesis of tryptophan and thiamine. D-Glyceraldehyde 3-phosphate is released as an aldehyde under the action of aldolase or triosephosphate isomerase. D-Glyceraldehyde 3-phosphate forms adducts with thiols .
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1 Cited Publications
Cat. No.: HY-B0863
CAS No.: 1071-83-6
Glyphosate, a non-selective systemic biocide with broad-spectrum activity, is an herbicidal derivative of the amino acid glycine. Glyphosate inhibits the enzymatic activity of the 5-endopyruvylshikimate 3-phosphate synthase (EPSPS) in the shikimic acid pathway, preventing the synthesis of the aromatic amino acids tyrosine, phenylalanine, and tryptophan. Glyphosate induces oxidative stress, neuroinflammation, and mitochondrial dysfunction, processes that lead to neuronal death by autophagia, necrosis, or apoptosis, as well as the appearance of behavioral and motor disorders .
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1 Cited Publications
Cat. No.: HY-W011910
CAS No.: 2642-37-7
Potassium 1H-indol-3-yl sulfate is a metabolite of tryptophan, produced by intestinal microorganisms and combined with sulfate in the liver before entering the circulatory system. Potassium 1H-indol-3-yl sulfate is a potent endogenous agonist of the aryl hydrocarbon receptor (AhR) and a urinary toxin. Potassium 1H-indol-3-yl sulfate can be used for research on kidney diseases .
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Cat. No.: HY-W142080
CAS No.: 153-91-3
Synonyms: α-MethylTryptophan
α-Methyl-DL-tryptophan (α-Methyltryptophan), a tryptophan derivative, is a selective SLC6A14 blocker. In estrogen receptor (ER)-positive breast cancer cells, α-Methyl-DL-tryptophan inhibits mTOR and activates autophagy and apoptosis. α-Methyl-DL-tryptophan also has the effect of reducing weight .
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Cat. No.: HY-N0707
CAS No.: 21339-55-9
Synonyms: 1-Methyl-L-Tryptophan; (S)-NLG-8189
(S)-Indoximod (1-Methyl-L-tryptophan) is an inhibitor of indoleamine 2,3-dioxygenase (IDO) (Ki: 19 μM). (S)-Indoximod can be used for the research of cancer and neurological disease .
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Cat. No.: HY-N15721
CAS No.: 1630745-39-9
Synonyms: Trp-CA
Tryptophan-cholic acid (Trp-CA) is a microbial amino acid-conjugated bile acid that acts as an endogenous ligand and agonist (EC50=9.6 μM) for the orphan G protein-coupled receptor (GPCR) MRGPRE (Mas-related G protein-coupled receptor family member E). Tryptophan-cholic acid is orally effective but has poor oral absorption and does not cross the blood-brain barrier. Tryptophan-cholic acid promotes the secretion of glucagon-like peptide GLP-1, thereby improving glucose tolerance in diabetic mice. Tryptophan-cholic acid improves glucose tolerance, promotes insulin secretion, and alleviates high-fat diet-induced hepatic steatosis without causing pruritus side effects. Tryptophan-cholic acid is primarily used in research on type 2 diabetes (T2D) .
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Cat. No.: HY-W011978
CAS No.: 1218-34-4
N-Acetyl-L-tryptophan is an antagonist of the neurokinin-1 receptor (NK-1R), disrupting the binding of substance P (SP) to NK-1R. This action provides neuroprotective effects, improving memory deficits and motor impairments. N-Acetyl-L-tryptophan is also an inhibitor of cytochrome c (Cytochrome c), and it exerts antioxidant and anti-inflammatory effects by inhibiting the expression of IL-1β and the activation of caspase-1. N-Acetyl-L-tryptophan holds promise for research in neurodegenerative and inflammatory diseases .
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Cat. No.: HY-W050025
CAS No.: 33468-35-8
Research Areas:  

Others

6-Chloro-L-tryptophan is a Tryptophan derivative. 6-Chloro-L-tryptophan can be used as a substrate for KtzQ .
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Cat. No.: HY-13718
CAS No.: 38101-59-6
Purity:  98.97%
Synonyms: H-Glu-Trp-OH; L-Glutamyl-L-Tryptophan
Oglufanide (H-Glu-Trp-OH) is a dipeptide immunomodulator isolated from calf thymus. Oglufanide inhibits vascular endothelial growth factor (VEGF). Oglufanide can stimulate the immune response to hepatitic C virus (HCV) and intracellular bacterial infections. Oglufanide shows antitumor and anti-angiogenesis activities .
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Cat. No.: HY-W012480
CAS No.: 54-12-6
Synonyms: (±)-Tryptophan
DL-Tryptophan ((±)-Tryptophan) is an orally effective aryl hydrocarbon receptor (AhR) agonist. DL-Tryptophan reduces the expression of pro-inflammatory cytokines IL-6, TNF-α, IL-1β, as well as liver injury markers aspartate aminotransferase and alanine aminotransferase, and alleviates hepatocyte apoptosis (apoptosis) in sepsis induced by cecal ligation and puncture. DL-Tryptophan can be used in the research of sepsis-related acute liver injury .
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Cat. No.: HY-N0623S5
CAS No.: 1233395-93-1
Synonyms: Tryptophan-d8; Tryptophane-d8
L-Tryptophan-d8 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .
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Cat. No.: HY-N0623S9
CAS No.: 133519-78-5
Synonyms: Tryptophan-d3; Tryptophane-d3
L-Tryptophan-d3 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .
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Cat. No.: HY-N0623S3
CAS No.: 81201-92-5
Synonyms: Tryptophan-1-13C; Tryptophane-1-13C
L-Tryptophan-1- 13C is the 13C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .
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Cat. No.: HY-W001542
CAS No.: 3416-18-0
5-Hydroxyoxindole is a structural analog of uric acid for its antioxidant. 5-Hydroxyoxindole has DPPH radical scavenging activities and lipid peroxidation-inhibitory activities. 5-Hydroxyoxindole is a product of partial metabolism of tryptophan involving conversion in the gut lumen of tryptophan to indole through the action of bacterial tryptophanase and tryptophan synthase. 5-Hydroxyoxindole is one of the main molecules responsible for the neurological symptoms of hepatic encephalopathy in rats. 5-Hydroxyoxindole can be used for the research of oxidative stress-mediated disorders .
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Cat. No.: HY-N0623S8
CAS No.: 204634-20-8
Synonyms: Tryptophan-15N2; Tryptophane-15N2
L-Tryptophan- 15N2 is the 15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .
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Cat. No.: HY-21045
CAS No.: 16626-02-1
Synonyms: L-5-FluoroTryptophan
Target:  

EAAT

Research Areas:  

Neurological Disease

5-Fluoro-L-tryptophan is a competitive vesicular glutamate transporter (VGLUT) inhibitor. 5-Fluoro-L-tryptophan is promising for research of diseases associated with the neurotransmitter systems .
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Cat. No.: HY-W011982
CAS No.: 87-32-1
Synonyms: N-Acetyl-DL-Tryptophan
Ac-DL-Trp-OH is an endogenous metabolite.
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