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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
391 Results for "
P1
" in MedChemExpress (MCE) Product Catalog:
Products (391)
391 Results for "P1" in MCE Product Catalog:
Cat. No.: HY-W024615
CAS No.: 25055-86-1
Synonyms: 3-(3-Methyl-3H-diazirin-3-yl)propanoic acid
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Me-diazirine-cooh (3-(3-Methyl-3H-diazirin-3-yl) propanoic acid) is a molecular building block containing an aliphatic diazirine ring. Me-diazirine-cooh undergoes orthogonal coupling in solid-phase peptide synthesis to introduce the Diazirine group into collagen-mimetic peptides. Me-diazirine-cooh is used to construct the photoaffinity probe P1 [1] .
Cat. No.: HY-P5959
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Synonyms: P1pal-7
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Cat. No.: HY-16124
CAS No.: 158382-37-7
Synonyms: TLK-286; TER286
Canfosfamide (TLK-286, TER286) is a glutathione analogue prodrug that is activated by glutathione S-transferase P1-1 and induces apoptosis. Canfosfamide also inhibits the catalytic kinase activity of DNA-dependent protein kinase (DNA-PK). Canfosfamide produces an anticancer alkylating agent and a glutathione derivative after activation. Canfosfamide can be used to research malignancies [1] .
Cat. No.: HY-E70047
CAS No.: 52725-57-2
Synonyms: A4GALT
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alpha-1,4-Galactosyltransferase (LgtC) (A4GALT) is a glycosphingolipid-specific glycosyltransferase. alpha-1,4-Galactosyltransferase (LgtC) transfers a galactose to the alpha-1,4 position of lactosylceramide to form globotriaosylceramide. alpha-1,4-Galactosyltransferase (LgtC) can be used for the synthesis of P1 blood group antigens [1] .
Cat. No.: HY-157269
CAS No.: 1069110-72-0
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J10-1 is a hapten small molecule. J10-1 accelerates peptide exchange in MHC class II molecules in an HLA-DM-independent manner, and its effect is not affected by the polymorphism of the P1 pocket of MHC class II molecules. J10-1 enhances the processes of peptide dissociation, peptide binding and peptide association of MHC class II molecules on the surface of B cells. J10-1 can be used for research on immunoregulation [1].
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Cat. No.: HY-P11316
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Cat. No.: HY-P5500
CAS No.: 959780-73-5
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1-Adamantaneethanol is an allele-selective MHC II class molecule loading enhancer (MHC loading enhancer, MLE) that enhances peptide loading and ligand exchange of HLA-DR molecules. 1-Adamantaneethanol targets the polymorphic P1 pocket of HLA-DR molecules and preferentially acts on HLA-DR subtypes with Gly at position β86, thereby stabilizing the peptide-receptor conformation and accelerating antigen loading. 1-Adamantaneethanol can be used in studies related to MHC II antigen presentation, peptide vaccines, adaptive immunity and tumor immunity [1] .
Cat. No.: HY-P5062A
Synonyms: Decanoyl-Arg-Val-Arg-Lys-chloromethylketone TFA
Cat. No.: HY-P10366
CAS No.: 652969-14-7
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Cat. No.: HY-N15117
CAS No.: 37331-24-1
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Cat. No.: HY-113273
CAS No.: 41708-91-2
Synonyms: Ap5A; P1,P5-Di(adenosine-5'-)pentaphosphate
Diadenosine pentaphosphate (Ap5A; P1,P5-Di(adenosine-5'-)pentaphosphate) is an endogenous generated diadenosine polyphosphate, possessing the dual identities of intracellular alarm signal and extracellular signaling molecule. Diadenosine pentaphosphate regulates calcium signaling in the nervous, cardiac and peripheral sensory systems by activating P2X1/P2X3/P2Y receptor and RyR2 channels (EC50 = 140 μM). Diadenosine pentaphosphate can be used in studies related to intracellular calcium release channels, cardiovascular diseases and nociception (pain) [1] .
Cat. No.: HY-179107
CAS No.: 3104477-57-5
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SLC6A19-IN-3 (Compound 83-P1-P2) is a potent, selective and orally active SLC6A19 inhibitor with an IC50 of 28 nM. SLC6A19-IN-3 can block SLC6A19-mediated transmembrane transport of phenylalanine, reducing intestinal absorption of phenylalanine from food and renal tubular reabsorption of phenylalanine. SLC6A19-IN-3 can be used for the research of metabolic disease, such as phenylketonuria [1].
Cat. No.: HY-P5062
CAS No.: 534615-50-4
Synonyms: Decanoyl-Arg-Val-Arg-Lys-chloromethylketone
Cat. No.: HY-P2317A
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Cat. No.: HY-P10618
CAS No.: 845623-61-2
Cat. No.: HY-P1832
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
