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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
156 Results for "
lateral
" in MedChemExpress (MCE) Product Catalog:
Products (156)
156 Results for "lateral" in MCE Product Catalog:
Cat. No.: HY-149187
CAS No.: 2170179-24-3
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LRRK2-IN-9 (compound 78) is a LRRK2 inhibitor that can be used in studies related to Parkinson's disease, Alzheimer's disease, and amyotrophic lateral sclerosis .
Cat. No.: HY-185934
CAS No.: 3060048-39-4
Synonyms: AD-1395762
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Ulenusiran (AD-1395762) is an siRNA duplex molecule that targets and inhibits the expression of the SOD1 gene. Ulenusiran can be used to study SOD1-associated amyotrophic lateral sclerosis .
Cat. No.: HY-N17885
CAS No.: 1443209-71-9
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Cat. No.: HY-P10466
CAS No.: 2377734-91-1
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Cat. No.: HY-P10466A
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Cat. No.: HY-P992436
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Cat. No.: HY-W015810R
CAS No.: 617-94-7
Cat. No.: HY-183933
CAS No.: 1355228-39-5
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K812 is an orally active ASK1 inhibitor with a 6 nM IC50 against ASK1. K812 selectively inhibits ASK1 activation. K812 inhibits glial activation in the lumbar spinal cord. K812 extends survival of SOD1 G93A transgenic mice. K812 can be used for the research of amyotrophic lateral sclerosis .
Cat. No.: HY-186253
CAS No.: 3129653-69-3
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TMEM175 agonist 1 is a TMEM175 agonist, with a human EC50 of 0.378 μM in FLIPR assays and a human EC50 of 0.886 μM in EP analyses. TMEM175 agonist 1 can be used in the research of Parkinson's disease, dementia with Lewy bodies, rapid eye movement sleep behavior disorder, amyotrophic lateral sclerosis, and lysosomal storage diseases .
Cat. No.: HY-P86835
Synonyms: ALPS2B antibody; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein antibody; Apoptosis related cysteine peptidase antibody; Apoptotic cysteine protease antibody; Apoptotic protease Mch-5 antibody; Apoptotic protease Mch5 antibody; CAP 4 antibody; CAP4 antibody; CASP-8 antibody; CASP8 antibody; ALPS2B antibody; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein antibody; Apoptosis related cysteine peptidase antibody
Cat. No.: HY-186254
CAS No.: 3129652-92-9
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TMEM175 agonist 2 is a TMEM175 agonist with an EC50 of 0.0446 μM in human FLIPR assays and an EC50 of 0.0453 μM in human TMEM175 EP assays. TMEM175 agonist 2 can be used in research related to Parkinson's disease, dementia with Lewy bodies, rapid eye movement sleep behavior disorder, amyotrophic lateral sclerosis, and lysosomal storage diseases .
Cat. No.: HY-181406
CAS No.: 3118633-46-5
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eIF2B activator-1 (Compound 7a) is a eIF2B activator with a pEC50 value of 7.3. eIF2B activator-1 exhibits significant hERG inhibitory activity, with a pIC50 value of 5.7. eIF2B activator-1 can be used in research related to Huntington's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS).
Cat. No.: HY-D3375
Cat. No.: HY-178049A
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UM-259 hydrochloride is a STING inhibitor with activity against both murine and human STING (including the STING R232 mutant). UM-259 hydrochloride inhibits STING-dependent signaling pathways, blocks STING oligomerization, and acts on human primary CD14 + monocytes. UM-259 hydrochloride can be used for research on amyotrophic lateral sclerosis, lupus erythematosus, Aicardi-Goutières syndrome, and infant-onset STING-associated vasculopathy .
Cat. No.: HY-172967A
CAS No.: 2762081-31-0
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(R)-SARM1-IN-5 is the (R)-enantiomer of SARM1-IN-5 (HY-172967). SARM1-IN-5 (compound 1-23-a) is a SARM1 inhibitor. SARM1-IN-5 can be used in the study of axonal degeneration related diseases such as Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS) .
Cat. No.: HY-186257
CAS No.: 3129652-66-7
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TMEM175 agonist 3 (Compound 123) is a TMEM175 agonist, with an EC50 of 0.044 μM in human TMEM175 FLIPR assays and an EC50 of 0.073 μM in human TMEM175 EP assays. TMEM175 agonist 3 can be used in the research of Parkinson's disease, dementia with Lewy bodies, rapid eye movement sleep behavior disorder, amyotrophic lateral sclerosis, and lysosomal storage diseases .
Cat. No.: HY-D3372
Synonyms: Dilinoleyl DiO
Cat. No.: HY-P991772
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Cat. No.: HY-129245
CAS No.: 78466-98-5
Synonyms: Hoe 175
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Razobazam (Hoe 175) is a benzodiazepine derivative with cognitive activity. Razobazam has been shown to improve learning performance in socially deprived rats. Razobazam increased avoidance scores by 18% after training. Razobazam caused significant changes in the optical density of certain areas of the rat brain, including a 22% decrease in the lateral habenula and a 25% increase in the ventral tegmental area. Razobazam also caused a 13% increase in optical density in the prefrontal cortex of rats .
Cat. No.: HY-182304
CAS No.: 1338489-62-5
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CLR01 sodium is a blood-brain barrier-permeable anti-aggregation agent. CLR01 sodium inhibits the de novo aggregation of Amyloid-β 40/42, α-synuclein, IAPP, tau protein and SOD1. CLR01 sodium reduces amyloid plaque burden in the cortex of triple-transgenic mice and improves the memory and motor abilities of these mice. CLR01 sodium can be used in research related to Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
