10652 Results for "

WERI-Rb1 cells

" in MedChemExpress (MCE) Product Catalog:
Products (10652)

10652 Results for "WERI-Rb1 cells" in MCE Product Catalog:

47
47 Cited Publications
Art. -Nr.: HY-10451
CAS. Nr.: 842133-18-0
Reinheit:  99.70%
Synonyms: JNJ 28431754
Target:  

SGLT

Forschungsgebiete:  

Metabolic Disease Cancer

Canagliflozin (JNJ 28431754) is a selective SGLT2 inhibitor with IC50s of 2 nM, 3.7 nM, and 4.4 nM for mSGLT2, rSGLT2, and hSGLT2 in CHOK cells, respectively [1].
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47
47 Cited Publications
Art. -Nr.: HY-I0383
CAS. Nr.: 928672-86-0
Synonyms: JNJ 28431754 hemihydrate
Target:  

SGLT

Forschungsgebiete:  

Metabolic Disease Cancer

Canagliflozin hemihydrate (JNJ28431754 hemihydrate) is a selective SGLT2 inhibitor with IC50s of 2 nM, 3.7 nM, and 4.4 nM for mSGLT2, rSGLT2, and hSGLT2 in CHOK cells, respectively [1].
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45
45 Cited Publications
Art. -Nr.: HY-P0151
CAS. Nr.: 213546-53-3
Target:  

NF-κB

Forschungsgebiete:  

Inflammation/Immunology

SN50 is a cell permeable inhibitor of NF-κB translocation.
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45
45 Cited Publications
Art. -Nr.: HY-15518
CAS. Nr.: 1005342-46-0
Reinheit:  99.91%
Target:  

IAP

Forschungsgebiete:  

Cancer

LCL161 is a IAP inhibitor which inhibits XIAP in HEK293 cell and cIAP1 in MDA-MB-231 cell with IC50s of 35 and 0.4 nM, respectively.
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45
45 Cited Publications
Art. -Nr.: HY-B0497
CAS. Nr.: 50-65-7
Synonyms: BAY2353
Forschungsgebiete:  

Infection Cancer

Niclosamide (BAY2353) is an orally active antihelminthic agent used in parasitic infection research [1]. Niclosamide is a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells . Niclosamide has biological activities against cancer, inhibits DNA replication in Vero E6 cells .
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45
45 Cited Publications
Art. -Nr.: HY-B0497C
CAS. Nr.: 1420-04-8
Synonyms: BAY2353 olamine
Forschungsgebiete:  

Infection Cancer

Niclosamide (BAY2353) olamine is an orally active antihelminthic agent used in parasitic infection research [1]. Niclosamide olamin is a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells . Niclosamide olamin has biological activities against cancer, and inhibits DNA replication in Vero E6 cells .
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45
45 Cited Publications
Art. -Nr.: HY-101625
CAS. Nr.: 334969-03-8
Reinheit:  99.94%
Synonyms: ON 01210
Target:  

Akt PI3K

Forschungsgebiete:  

Cancer

Recilisib (ON 01210) is a radioprotectant, which can activate AKT, PI3K activities in cells [1].
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45
45 Cited Publications
Art. -Nr.: HY-16591
CAS. Nr.: 1260251-31-7
Synonyms: TL32711
Target:  

IAP Apoptosis HIV

Forschungsgebiete:  

Cancer

Birinapant (TL32711), a bivalent Smac mimetic, is a potent antagonist for XIAP and cIAP1 with Kds of 45 nM and less than 1 nM, respectively. Birinapant (TL32711) induces the autoubiquitylation and proteasomal degradation of cIAP1 and cIAP2 in intact cells, which results in formation of a RIPK1: caspase-8 complex, caspase-8 activation, and induction of tumor cell death. Birinapant (TL32711) targets TRAF2-associated cIAPs and abrogates TNF-induced NF-κB activation.
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44
44 Cited Publications
Art. -Nr.: HY-D0984A
CAS. Nr.: 115532-50-8
Synonyms: T668
Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms [1].
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44
44 Cited Publications
Art. -Nr.: HY-100564
CAS. Nr.: 1441190-66-4
Reinheit:  99.95%
Synonyms: 2'-3'-cyclic GMP-AMP
2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP is produced in mammalian cells in response to DNA in the cytoplasm [1].
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44
44 Cited Publications
Art. -Nr.: HY-100564A
CAS. Nr.: 2734858-36-5
Reinheit:  99.63%
Synonyms: 2'-3'-cyclic GMP-AMP sodium
2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP sodium binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP sodium is produced in mammalian cells in response to DNA in the cytoplasm [1].
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44
44 Cited Publications
Art. -Nr.: HY-D0952
CAS. Nr.: 494-38-2
Acridine Orange base is a cell-permeable fluorescent dye that stains organisms (bacteria, parasites, viruses, etc.) bright orange and, when used under appropriate conditions (pH=3.5, Ex=460 nm), distinguishes human cells in green for detection by fluorescence microscopy. Acridine Orange base fluoresces green when bound to dsDNA (Ex=488, Em=520-524) and red when bound to ssDNA (Ex=457, Em=630-644) or ssRNA (Ex=457, Em=630-644), also can be used in cell cycle assays [1] .
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44
44 Cited Publications
Art. -Nr.: HY-N1428
CAS. Nr.: 77-92-9
Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries [1] .
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44
44 Cited Publications
Art. -Nr.: HY-K0314

MCE ATP Assay Kit provides a rapid method to measure intracellular ATP. The kit is suitable for ATP determination in cells, tissue, and other biological samples.

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43
43 Cited Publications
Art. -Nr.: HY-K1078

MCE One Step TUNEL Apoptosis Detection Kit (FITC) provides a rapid and convenient method to detect cell apoptosis. After staining cells with this kit, live cells have no fluorescence, apoptosis cells show green fluorescence.

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43
43 Cited Publications
Art. -Nr.: HY-K1014

MCE PolyFast Transfection Reagent consists of cationic polymers and can introduce nucleic acids (DNA or RNA) into eukaryotic cells efficiently, including some hard-to-transfect cells.

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43
43 Cited Publications
Art. -Nr.: HY-N0504
CAS. Nr.: 75330-75-5
Synonyms: Mevinolin
Lovastatin (Mevinolin) is a cell-permeable HMG-CoA reductase inhibitor used to lower cholesterol.
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43
43 Cited Publications
Art. -Nr.: HY-119240
CAS. Nr.: 324759-76-4
Reinheit:  99.05%
Target:  

PERK Autophagy

Forschungsgebiete:  

Neurological Disease Cancer

CCT020312 is a selective EIF2AK3/PERK activator. CCT020312 elicits EIF2A phosphorylation in cells.
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43
43 Cited Publications
Art. -Nr.: HY-19987
CAS. Nr.: 853220-52-7
Target:  

Wnt

Forschungsgebiete:  

Cancer

BML-284 is a potent and cell-permeable Wnt signaling activator. BML-284 induces TCF-dependent transcriptional activity with an EC50 of 700 nM [1].
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42
42 Cited Publications
Art. -Nr.: HY-D0989
CAS. Nr.: 145037-81-6
Rhod-2 is a high-affinity visible light excitation wavelength Ca 2+ fluorescent probe, Rhod-2, AM is an acetyl methyl ester derivative of Rhod-2, which has cell membrane permeability and can easily enter cells with simple culture. Once it enters the cell, it is sheared by its lactesterase to produce Rhod-2 without membrane permeability, which remains in the cell to perform the corresponding physiological functions. Maximum excitation/emission wavelength: 549/578 nm [1].
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