![Bis[2-(4-hydroxyphenylthio)ethoxy]methane](https://file.medchemexpress.com/product_pic/hy-w744923.gif "Click to View Bis[2-(4-hydroxyphenylthio)ethoxy]methane Product Detail")
Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2419 Results for "
decrease
" in MedChemExpress (MCE) Product Catalog:
Products (2419)
2419 Results for "decrease" in MCE Product Catalog:
Cat. No.: HY-B1455S
CAS No.: 1356933-72-6
Cat. No.: HY-D3111
CAS No.: 1240465-12-6
Target:
Research Areas:
DBHA is a long-wavelength polarity-sensitive fluorescent probe based on Nile Red. Under the catalysis of Pd (OAc)2/TPPTS, DBHA site-selectively labels protein tyrosine residues via a π-allyl palladium complex intermediate. Utilizing the property that its maximum emission wavelength blue-shifts with decreasing local polarity (650 nm in aqueous solution → 584-608 nm in hydrophobic domains), it detects changes in local polarity and conformation of protein tyrosine domains under acid/thermal denaturation conditions. DBHA can be used in studies related to SOD1-associated oxidative stress neurodegenerative diseases .
Cat. No.: HY-N0060BS
CAS No.: 860605-59-0
Synonyms: (E)-Coniferic acid-d3
Category:
Cat. No.: HY-N6674
CAS No.: 733035-26-2
Synonyms: ECO-4601; TLN-4601; BU 4664L
Research Areas:
Diazepinomicin (ECO-4601) is a reagent with both anticancer and antibacterial activities. . Diazepinomicin decreases Bcl2 and BAX expression, induces dose-dependent cell death and apoptotic bodies, and inhibits Ras-MAPK signaling and tumor growth/proliferation. Diazepinomicin induces apoptosis through caspase 3 activation, PARP cleavage, cytochrome C release, loss of membrane potential, and DNA fragmentation, independent of PBR expression. Diazepinomicin binds PBR/TSPO and displaces PK11195 through its farnesyl side chain rather than the dibenzodiazepinone core. Diazepinomicin can be used in research on hepatocellular carcinoma, Gram-positive bacterial infections, and glioma .
Cat. No.: HY-N7506
CAS No.: 178765-49-6
Synonyms: Delta3,2-Hydroxylbakuchiol
Cat. No.: HY-P11358
CAS No.: 159718-10-2
Research Areas:
Cat. No.: HY-P4882
CAS No.: 183449-57-2
Target:
Research Areas:
(Pyr3)-Amyloid β-Protein (3-42) is an N-terminally truncated and pyroglutamate-modified amyloid β peptide. (Pyr3)-Amyloid β-Protein (3-42) spontaneously aggregates into soluble oligomers and β-sheet-structured fibrils, causing neuronal cytotoxicity and leading to decreased expression of postsynaptic density protein 95 (PSD-95) in mouse cortex, thereby inducing synaptic dysfunction in spatial and short-term memory. (Pyr3)-Amyloid β-Protein (3-42) can be used for research on Alzheimer's disease .
Cat. No.: HY-P991595
CAS No.: 2790610-50-1
Target:
Research Areas:
Cat. No.: HY-W145486
CAS No.: 299-28-5
Cat. No.: HY-W271506
CAS No.: 10135-38-3
Synonyms: 3,3,5,5-Tetramethyl-1-pyrroline 1-oxide
Research Areas:
TMPO (3,3,5,5-Tetramethyl-1-pyrroline 1-oxide) is a spin trap targeting free radicals. TMPO is capable of scavenging superoxide, hydroxyl radicals and inhibits thymocyte apoptosis with EC50 values of 19.1 mM (MPS-induced) to 30.7 mM (Etoposide-induced) for inhibiting DNA fragmentation. TMPO reacts with intracellular free radicals to form stable nitroxide radical products, reducing oxidative stress (e.g., decreasing peroxide levels, maintaining glutathione content) and blocking oxidative events in the apoptotic pathway. TMPO is promising for research of apoptosis in immune cells like thymocytes .
Cat. No.: HY-W283930
CAS No.: 132858-26-5
Research Areas:
YHV98-4 is a selective, blood-brain barrier-permeable Hv1 inhibitor with an IC50 of 0.7 μM. YHV98-4 reduces ROS production and restores the SHP-1-pAKT signaling pathway. YHV98-4 decreases the spread of hyperphosphorylated Tau protein. YHV98-4 alleviates inflammation and produces analgesic effects. YHV98-4 improves cognitive function in mouse models of Alzheimer's disease. YHV98-4 can be used in research related to inflammatory pain, neuropathic pain and Alzheimer's disease .
Cat. No.: HY-W414644
CAS No.: 229977-93-9
Target:
Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
Fluacrypyrim, a Miticide, is a STAT3 inhibitor. Fluacrypyrim significantly increases the protein tyrosine phosphatases(PTPs) activity. Fluacrypyrim inhibits the growth of leukemia cells by a predominant G1 arrest with significant decrease of the protein and mRNA levels of cyclin D1. Fluacrypyrim selectively inhibits STAT3 signaling, inducing growth arrest and apoptosis in STAT3-dependent cancer cells. Fluacrypyrim mitigates IR-induced hematopoietic system injury mainly by preventing apoptosis in the HSCs. Fluacrypyrim demonstrates significant analgesic and anti-inflammatory effects by inhibiting uterine smooth muscle contraction and inflammatory responses .
Cat. No.: HY-W419589
CAS No.: 16545-23-6
Research Areas:
Xanthomicrol is extracted from the resin of the plant called Chinese bellflower (a member of the Scrophulariaceae family) and is a monoamine oxidase (MAOs) inhibitor. Xanthomicrol has anti-tumor and anti-inflammatory properties, with IC50 values of 0.88 and 1.69 μg/mL in HL60 and K562 cells. Xanthomicrol's the main metabolite of 5DT in mouse colon, and it can reduce levels of iNOS protein and mRNA, as well as COX-2 protein levels. Additionally, Xanthomicrol decreases the production of the pro-inflammatory cytokine IL-1β and induces the expression of the antioxidant enzyme HO-1 .
Cat. No.: HY-W584165
CAS No.: 13983-17-0
Research Areas:
Wollastonite is a white, chain-structured pyroxene silicate mineral with biocompatibility, biodegradability, osteogenicity and antibacterial properties. Wollastonite induces transient pulmonary inflammatory responses, reversible alveolar macrophage responses, early inflammatory/proliferative mesothelial cell responses, ROS production, and mild chronic pulmonary interstitial inflammation in rats. Wollastonite induces osteogenic differentiation, promotes bone growth, supports angiogenesis, and facilitates the formation of hydroxycarbonate apatite on its surface. Wollastonite enhances the strength, bioactivity and biodegradability of hydroxyapatite scaffolds, and is used to construct porous bone tissue engineering scaffolds. Wollastonite is applied in research related to diseases such as bronchitis, decreased lung function and bone defects .
Cat. No.: HY-W744923
CAS No.: 93589-69-6
Synonyms: DD-70
Target:
Research Areas:
Bis[2-(4-hydroxyphenylthio) ethoxy]methane (DD-70) is a Bisphenol A (HY-18260) substitute and a COX-1 inhibitor. Bis[2-(4-hydroxyphenylthio) ethoxy]methane blocks platelet aggregation induced by Arachidonic acid (HY-109590) and U-46619 (HY-108566). Bis[2-(4-hydroxyphenylthio) ethoxy]methane alters hemostatic function. Bis[2-(4-hydroxyphenylthio) ethoxy]methane reduces embryonic survival rate, decreases embryonic mass and increases gallbladder mass in chicken embryos .
Cat. No.: HY-W750960R
CAS No.: 1377605-22-5
Biotinylated isoxazole (Standard) is the analytical standard of Biotinylated isoxazole (HY-W750960). This product is intended for research and analytical applications. Biotinylated isoxazole is a chemical probe that selectively precipitates proteins containing prion-like low-complexity domains and Cross-β prion-like polymers through recognition of Cross-β structure. Biotinylated isoxazole induces precipitation of proteins containing intrinsically disordered regions through microcrystal formation in solution. Biotinylated isoxazole enables enrichment of Amyloid oligomers for ELISA-based detection. Biotinylated isoxazole decreases Gems and increases misfolded PFN1 aggregates .
Cat. No.: HY-W777365
CAS No.: 1215408-17-5
Synonyms: EDTA-13C4
Cat. No.: HY-Y0682S2
CAS No.: 15251-22-6
Synonyms: EDTA-d4
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
