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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
44 Results for "
3-IP
" in MedChemExpress (MCE) Product Catalog:
Products (44)
44 Results for "3-IP" in MCE Product Catalog:
76
11
11 Cited Publications
Synonyms: (-)-Xestospongin C
Category:
Target:
8
8 Cited Publications
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MCU-i4 blocks the IP3-dependent mitochondrial Ca 2+-uptake, maintaining the gatekeeping role of their target .
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Neomycin, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin is a known phospholipase C (PLC) inhibitor. Neomycin potently inhibits both the nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis. Neomycin inhibits IP3-mediated Ca 2+ release, MgATP-dependent Ca 2+ uptake, and electrical excitation-evoked skeletal muscle Ca 2+ transients. Neomycin depletes gut microbiota in specific mouse models, causes hearing impairment, and kidney damage with prolonged exposure. Neomycin can be used for the research of cancer .
Cat. No.: HY-169396
CAS No.: 2769753-10-6
Synonyms: TL13-87
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Ligands for Target Protein for PROTAC Microtubule/Tubulin YTHDF CDK Btk FLT3 Aurora Kinase Tyrosinase ULK Itk
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TAE648 is a target protein ligand of PROTAC SK-3-91 (HY-137341) (Ligand for Target Protein for PROTAC). TAE648 can be used for synthesis PROTAC . TAE648 decreases monolayer-cultured SKOV3ip1 cell viability .
Cat. No.: HY-177285
CAS No.: 1161925-41-2
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NVP-BQS481 (Compound 1) is a selective Kinesin spindle protein-5 (Eg5) inhibitor with an IC50< 0.5 nM. NVP-BQS481 has significant antimitotic and antitumor activity (IC50: 0.0.9 nM for SK-OV-3ip cells). NVP-BQS481 can be used as a cytotoxic payload for synthesis of antibody-drug conjugates (ADCs) .
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IP6K2-IN-2 (Compound 6) is an IP6K2 inhibitor, with IC50 values of 0.58 μM (IP6K2), 0.86 μM (IP6K1) and 3.08 μM (IP6K3). IP6K2-IN-2 can be used in research of obesity .
Cat. No.: HY-W009458
CAS No.: 3318-43-2
Synonyms: 3-IP sodium
Cat. No.: HY-177079S
CAS No.: 2759134-55-7
Cat. No.: HY-RS11313
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PSMC3IP Human Pre-designed siRNA Set A contains three designed siRNAs for PSMC3IP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS11562
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RAB3IP Human Pre-designed siRNA Set A contains three designed siRNAs for RAB3IP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS06549
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IER3IP1 Human Pre-designed siRNA Set A contains three designed siRNAs for IER3IP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS10535
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PIK3IP1 Human Pre-designed siRNA Set A contains three designed siRNAs for PIK3IP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14970
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TRAF3IP1 Human Pre-designed siRNA Set A contains three designed siRNAs for TRAF3IP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14971
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TRAF3IP2 Human Pre-designed siRNA Set A contains three designed siRNAs for TRAF3IP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14972
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TRAF3IP3 Human Pre-designed siRNA Set A contains three designed siRNAs for TRAF3IP3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS22078
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Traf3ip2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Traf3ip2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-175384
Synonyms: Ins(3)P1 sodium salt; 3-IP1 sodium
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D-myo-Inositol-3-phosphate (sodium) is one of the members in inositol phosphate family of second messengers that play an important role in transmitting cellular signals. D-myo-Inositol-3-phosphate (sodium) can be formed by the dephosphorylation of polyphosphate inositols .
Cat. No.: HY-172803
CAS No.: 2723569-00-2
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Ferroptosis inducer-7 is an orally active and selective ferroptosis inducer via inositol 1,4,5-trisphosphate receptor (IP3R)/calcium release-activated calcium channel protein (ORAI). Ferroptosis inducer-7 exhibits a notable effect in alleviating anemia symptoms, suppressing bone marrow CTLs activation, and improving hematopoietic function in immune-mediated bone marrow failure. Ferroptosis inducer-7 can be studied in research for aplastic anemia .
Cat. No.: HY-RS17178
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Pik3ip1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pik3ip1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
