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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
33 Results for "
APPSwe/Ind
" in MedChemExpress (MCE) Product Catalog:
Products (33)
33 Results for "APPSwe/Ind" in MCE Product Catalog:
14
14 Publications Verification
Synonyms: Ind 58359; R115777
Target:
Tipifarnib (IND 58359) binds to and inhibits farnesyltransferase (FTase) with an IC50 of 0.86 nM. Antineoplastic activity and antiparasitic activity .
6
6 Cited Publications
Synonyms: BSI-201; NSC-746045; Ind-71677
Target:
Research Areas:
Iniparib (BSI-201) is an irreversible inhibitor of PARP1, used in the research of triple negative breast cancer.
2
2 Cited Publications
Research Areas:
DC-LC3in-D5 acts as an autophagy inhibitor by attenuating LC3B lipidation. DC-LC3in-D5 binds with LC3B. DC-LC3in-D5 disrupts the LC3B-LBP2 interaction with an IC50 of 200 nM. DC-LC3in-D5 may contribute to anti-HCV or combination researchs in cancer through inhibiting autophagy .
2
2 Cited Publications
Cat. No.: HY-P72790
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL22; Macrophage-Derived Chemokine; Prev. SCYA22; CC Chemokine STCP-1; MDC; MDC(1-69); A-152E5.1; MGC34554; DC/B-CK; Stimulated T Cell Chemotactic Protein 1; STCP-1; Stimulated T-Cell Chemotactic Protein 1; ABCD-1; Small Inducible Cytokine A22; Small Ind
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-W110883
CAS No.: 3618-43-7
1
1 Cited Publications
Cat. No.: HY-P7248
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CCL22; Macrophage-Derived Chemokine; Prev. SCYA22; CC Chemokine STCP-1; MDC; MDC(1-69); A-152E5.1; MGC34554; DC/B-CK; Stimulated T Cell Chemotactic Protein 1; STCP-1; Stimulated T-Cell Chemotactic Protein 1; ABCD-1; Small Inducible Cytokine A22; Small Ind
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P71082
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: S100A6; Protein S100-A6; Prev. CACY; S100 Calcium-BInding Protein A6 (Calcyclin); PRA; S100 Calcium-BInding Protein A6; Calcyclin; S100 Calcium-BInding Protein; CABP; Protein S100; 2A9; S10A6; Prolactin Receptor-Associated Protein; 5B10; Growth Factor-Ind
Species:
Human
Source:
E. coli
Target:
Research Areas:
Neutral Red (IND) is an organic dye commonly used in biology and cytology laboratories. It can be used to stain living cells, secreted proteins and other molecular structures, etc., and has a wide range of applications in cell imaging and staining. In addition, Neutral Red (IND) is widely used in industrial fields such as water treatment, food processing and paper manufacturing, for example as an indicator or colorant.
Cat. No.: HY-W110927
CAS No.: 130-22-3
Cat. No.: HY-W110794
CAS No.: 548-62-9
Synonyms: Ind-Cl
Target:
Research Areas:
Indazole-Cl (Ind-Cl) is an Estrogen receptor (ER)-β-specific agonist with inflammatory effect. Indazole-Cl inhibits cyclooxygenase-2 exression reduction induced by hypoxia. And Indazole-Cl inhibits ROS production. Indazole-Cl also inhibits cell migration and invasion by hypoxia increased by hypoxia. Indazole-Cl is potent inhibitor of hypoxia-induced inflammation in vascular smooth muscle cells (VSMCs) .
Synonyms: Ind-58359 S enantiomer; (S)-(-)-R-115777
Target:
Research Areas:
Tipifarnib S enantiomer is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM. Tipifarnib S enantiomer is the less active isomer.
Cat. No.: HY-W140928
CAS No.: 4430-25-5
Synonyms: TBPB, Ind
Target:
Research Areas:
Tetrabromophenol blue, IND is a biochemical reagent.
Cat. No.: HY-W110925
CAS No.: 1324-80-7
Cat. No.: HY-118426
CAS No.: 192185-68-5
Synonyms: (Rac)-Ind 58359; (Rac)-R115777
Target:
Research Areas:
(Rac)-Tipifarnib ((Rac)-IND 58359; (Rac)-R115777) is a potent farnesyl protein transferase inhibitor that specifically targets the pro-tailation process of Ras proteins. (Rac)-Tipifarnib showed significant in vivo antitumor effects after oral administration to mice .
Cat. No.: HY-161163
CAS No.: 1888473-12-8
Target:
Research Areas:
IND 1316 is an orally active, blood-brain barrier permeable AMPK activator with neuroprotective effects in animal models of Huntington's disease. IND 1316 can be used for research on neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease .
Cat. No.: HY-W110882
CAS No.: 3688-92-4
Cat. No.: HY-124375
CAS No.: 1426047-52-0
Target:
Research Areas:
IND81 is an orally active antiprion with IC50 value of 1.95 μM. IND81 reduces abnormal, misfolded, disease-causing forms of benign prion proteins that are normally present on or within cells .
Target:
Research Areas:
IND24 is a potent antiprion agent with an EC50 value of 1.27 µM. IND24 decreases abnormal, misfolded, pathogenic forms of benign normally occurring prion protein on the cell surface or inside the cell .
Cat. No.: HY-115360
CAS No.: 10024-04-1
Target:
Research Areas:
IND45193 is a compound used to inhibit prion disease, with activity in reducing PrP(Sc) levels. In cells infected with prions, IND45193 can reduce PrP(Sc) levels, and its activity was determined through screening of multiple cell types and concentration-effect relationship studies.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
