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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
37 Results for "
AT1R
" in MedChemExpress (MCE) Product Catalog:
Products (37)
37 Results for "AT1R" in MCE Product Catalog:
248
248 Publications Verification
Synonyms: Angiotensin II; Ang II; DRVYIHPF
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248
248 Publications Verification
Synonyms: Angiotensin II acetATe; Ang II acetATe; DRVYIHPF acetATe
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Research Areas:
Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology Cancer
248
248 Publications Verification
Synonyms: Angiotensin II TFA; Ang II TFA; DRVYIHPF TFA
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Olmesartan (RNH-6270) is an angiotensin II receptor (AT1R) antagonist used to treat high blood pressure [1] .
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3
3 Cited Publications
Cat. No.: HY-P2141A
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Cat. No.: HY-P3137
CAS No.: 812644-79-4
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Synonyms: DINP
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Diisononyl phthalate (DINP) is an orally active polyvinyl chloride plasticizer and indirect food additive. Diisononyl phthalate activates the ACE/AT1R axis and inhibits the production of NO. Diisononyl phthalate reduces the expression of eNOS. Diisononyl phthalate induces increased blood pressure in mice. Diisononyl phthalate induces monocytic leukemia in rats. Diisononyl phthalate can be used in hypertension-related research [1] .
Cat. No.: HY-P1540
CAS No.: 13602-53-4
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Cat. No.: HY-17004S1
CAS No.: 1185144-74-4
Synonyms: RNH-6270-d6
Cat. No.: HY-P4685
CAS No.: 185461-45-4
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Cat. No.: HY-P3136A
Synonyms: TRV120055 hydrochloride
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Cat. No.: HY-P2381
CAS No.: 2410957-04-7
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Cat. No.: HY-17004S
CAS No.: 1420880-41-6
Synonyms: RNH-6270-d4
Cat. No.: HY-146436
CAS No.: 2848719-76-4
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AT1R antagonist 2 (compound 6) is a potent AT1R selective ligand. AT1R antagonist 2 exhibits a fair AT1R affinity, with a Ki of 26 nM [1].
Cat. No.: HY-146431
CAS No.: 2848719-80-0
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AT1R antagonist 1 (compound 10) is a potent AT1R selective ligand. AT1R antagonist 1 exhibits a fair AT1R affinity, with a Ki of 8.5 nM [1].
Cat. No.: HY-13948BS
Purity: 98.11%
Synonyms: Angiotensin II-13C6,15N TFA; Ang II-13C6,15N TFA; DRVY(I-13C6,15N)HPF TFA
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Cat. No.: HY-159090
CAS No.: 3053482-15-5
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AT1R antagonist 3 (Compound 1) is an antagonist for angiotensin II type 1 receptor (AT1R) and an inhibitor for calcium channel type-L CaV1.2 (IC50=0.57 μM). AT1R antagonist 3 exhibits vasodilation efficacy in solated rat aorta (10 μM, 88.7%) and antihypertensive efficacy in rat models [1].
Cat. No.: HY-P10830
CAS No.: 161146-12-9
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Cat. No.: HY-180443
CAS No.: 2982582-16-9
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AT1R antagonist 4 (Example 26) is an AT1R antagonist. AT1R antagonist 4 shows excellent antagonistic activity against calcium influx in cells stably expressing AT1 receptors and ETA receptors. AT1R antagonist 4 can be used in kidney disease research [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
