1091 Results for "

Aceturic acid-13C2, 15N

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Liraglutide

43 Publications Verification

Cat. No.: HY-P0014

CAS No.: 204656-20-2

Target:

GCGR GLP Receptor

Research Areas:

Neurological Disease Metabolic Disease Inflammation/Immunology

Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus.

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Liraglutide TFA

43 Publications Verification

Cat. No.: HY-P0014B

Target:

GLP Receptor

Research Areas:

Metabolic Disease

Liraglutide (TFA) is an agonist of glucagon-like peptide 1 receptor (GLP-1). Liraglutide (TFA) can activate GLP-1, leading to the release of insulin in the presence of increased glucose concentration. Liraglutide (TFA) also reduces glucagon secretion in a glucose-dependent manner. Liraglutide (TFA) can be studied in research on type 2 diabetes .

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L-Glutamine-15N-1

4 Cited Publications

Cat. No.: HY-N0390S9

CAS No.: 59681-32-2

Synonyms: L-Glutamic acid 5-amide-¹⁵N-1

L-Glutamine- ¹⁵N-1 is the ¹⁵N-labeled L-Glutamine (HY-N0390). L-Glutamine is an orally active nutritional agent and cellular metabolism regulator. L-Glutamine is taken up in a Na ⁺-dependent manner and targets multiple key molecules including glutaminase, mTORC1, NF-κB, STAT-3 and HIF-1α. L-Glutamine enhances glutaminolytic catabolism, drives the conversion of glutamate to α-ketoglutarate, thereby regulating gene expression, integrating metabolic signals, mediating glutamine flux and maintaining redox homeostasis. L-Glutamine also promotes cell proliferation, osteogenic differentiation and fracture healing, exerts neuroprotective and cardioprotective effects, and inhibits osteoarthritis. L-Glutamine can be applied to research related to osteoporosis, osteoarthritis, ischemic stroke and acute cantharidin-induced cardiotoxicity .

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L-Glutamine-15N

4 Cited Publications

Cat. No.: HY-N0390S

CAS No.: 80143-57-3

Synonyms: L-Glutamic acid 5-amide-¹⁵N

L-Glutamine- ¹⁵N is the ¹⁵N-labeled L-Glutamine (HY-N0390). L-Glutamine is an orally active nutritional agent and cellular metabolism regulator. L-Glutamine is taken up in a Na ⁺-dependent manner and targets multiple key molecules including glutaminase, mTORC1, NF-κB, STAT-3 and HIF-1α. L-Glutamine enhances glutaminolytic catabolism, drives the conversion of glutamate to α-ketoglutarate, thereby regulating gene expression, integrating metabolic signals, mediating glutamine flux and maintaining redox homeostasis. L-Glutamine also promotes cell proliferation, osteogenic differentiation and fracture healing, exerts neuroprotective and cardioprotective effects, and inhibits osteoarthritis. L-Glutamine can be applied to research related to osteoporosis, osteoarthritis, ischemic stroke and acute cantharidin-induced cardiotoxicity .

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Cagrilintide

3 Cited Publications

Cat. No.: HY-P3462

CAS No.: 1415456-99-3

Target:

CGRP Receptor

Research Areas:

Metabolic Disease

Cagrilintide is an investigational novel long-acting acylated amylin analogue, acts as nonselective amylin receptors (AMYR) and calcitonin G protein-coupled receptor (CTR) agonist. Cagrilintide induces significant weight loss and reduces food intake. Cagrilintide has the potential for the research of obesity .

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Cagrilintide acetate

3 Cited Publications

Cat. No.: HY-P3462A

Target:

CGRP Receptor

Research Areas:

Metabolic Disease

Cagrilintide acetate is a non-selective AMYR/CTR agonist and long-acting acylated amylase analogue. Cagrilintide acetate causes a reduction in food intake and significant weight loss in a dose-dependent manner. Cagrilintide acetate can be used in obesity studies .

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L-Cysteine-13C3,15N

2 Cited Publications

Cat. No.: HY-Y0337S

CAS No.: 202406-97-1

L-Cysteine- ¹³C₃, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans .

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Hypoxanthine-15N4

2 Cited Publications

Cat. No.: HY-N0091S7

CAS No.: 77910-30-6

Synonyms: Purin-6-ol-¹⁵N₄; Sarcine-¹⁵N₄

Hypoxanthine- ¹⁵N₄ is the ¹⁵N labeled Hypoxanthine . Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia .

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Glutathione oxidized-13C4,15N2

2 Cited Publications

Cat. No.: HY-D0844S

CAS No.: 1416898-83-3

Synonyms: L-Glutathione oxidized-¹³C₄,¹⁵N₂; GSSG-¹³C₄,¹⁵N₂; Oxiglutatione-¹³C₄,¹⁵N₂

Glutathione oxidized- ¹³C₄, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Glutathione oxidized (HY-D0844). Glutathione oxidized is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes .

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Terephthalic acid-13C2

2 Cited Publications

Cat. No.: HY-W010098S1

CAS No.: 121191-53-5

Terephthalic acid- ¹³C₂ is the ¹³C-labeled Terephthalic acid. Terephthalic acid is an isomer and a precursor of polyester PET, which can be used to make clothing and plastics. Terephthalic acid can be used to build skin tumor models .

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L-Isoleucine-15N

1 Cited Publications

Cat. No.: HY-N0771S2

CAS No.: 59935-30-7

L-Isoleucine-15N is the 15N-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid. L-Isoleucine is an essential amino acid .

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L-Leucine-13C6,15N

1 Cited Publications

Cat. No.: HY-N0486S8

CAS No.: 202406-52-8

L-Leucine- ¹³C₆, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .

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L-Cysteine-15N

1 Cited Publications

Cat. No.: HY-Y0337S1

CAS No.: 204523-09-1

L-Cysteine- ¹⁵N is the ¹⁵N-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans .

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L-Arginine-15N2 hydrochloride

1 Cited Publications

Cat. No.: HY-N0455AS

CAS No.: 204633-92-1

Synonyms: (S)-(+)-Arginine-15N2 hydrochloride

L-Arginine- ¹⁵N₂ (hydrochloride) is the ¹⁵N-labeled L-Arginine (hydrochloride). L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

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Upadacitinib-15N,d2

1 Cited Publications

Cat. No.: HY-W727879

Synonyms: ABT-494-¹⁵N,d₂

Upadacitinib- ¹⁵N,d₂ (ABT-494- ¹⁵N,d₂) is the deuterium-labeled Upadacitinib (HY-19569). Upadacitinib- ¹⁵N,d₂ (ABT-494) is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC₅₀=43 nM). Upadacitinib- ¹⁵N,d₂ (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib- ¹⁵N,d₂ (ABT-494) can be used for several autoimmune disorders research .

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L-Valine-15N

1 Cited Publications

Cat. No.: HY-N0717S

CAS No.: 59935-29-4

Synonyms: (S)-Valine-¹⁵N

L-Valine- ¹⁵N ((S)-Valine- ¹⁵N) is the ¹⁵N-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase .

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Metronidazole-13C2,15N2

1 Cited Publications

Cat. No.: HY-B0318S

CAS No.: 1173020-03-5

Metronidazole- ¹³C₂, ¹⁵N₂ is the ¹³C-labeled and ¹⁵N-labeled Metronidazole. Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.

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L-Argininosuccinic acid-13C6,15N4 barium, dihydrate

1 Cited Publications

Cat. No.: HY-143876S

CAS No.: 2483829-90-7

L-Argininosuccinic acid- ¹³C₆, ¹⁵N₄ (barium, dihydrate) is a ¹⁵N-labeled and ¹³C-labled labeled L-Argininosuccinic acid (barium, dihydrate) .

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Adenosine monophosphate-13C10,15N5 dilithium

1 Cited Publications

Cat. No.: HY-A0181S

Synonyms: AMP-13C10,15N5 dilithium

Adenosine monophosphate- ¹³C₁₀, ¹⁵N₅(AMP- ¹³C₁₀, ¹⁵N₅) is the ¹³C-labeled and ¹⁵N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .

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Uric acid-15N2

1 Cited Publications

Cat. No.: HY-B2130S1

CAS No.: 62948-75-8

Target:

Isotope-Labeled Compounds Endogenous Metabolite Reactive Oxygen Species (ROS)

Uric acid- ¹⁵N₂ is the ¹⁵N-labeled Uric acid (HY-B2130). Uric acid is an orally active oxygen free radical scavenger that helps maintain stable blood pressure and combat oxidative stress. Uric acid can scavenge ROS, such as singlet oxygen and peroxynitrite, and inhibit lipid peroxidation. Uric acid can be used as a modeling agent in research on hyperuricemia-induced hypertension models .

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