49 Results for "

Amino Acid Decarboxylase

" in MedChemExpress (MCE) Product Catalog:
Products (49)

49 Results for "Amino Acid Decarboxylase" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-B0404A
CAS No.: 14919-77-8
Synonyms: Ro 4-4602 hydrochloride
Target:  

Pyruvate Kinase

Research Areas:  

Neurological Disease Cancer

Benserazide hydrochloride (Serazide) is an aromatic L-amino acid decarboxylase (AADC) and L-DOPA decarboxylase inhibitor. Benserazide hydrochloride is also a PKM2 inhibitor. Benserazide hydrochloride directly binds to and blocks PKM2 enzyme activity, leading to inhibition of aerobic glycolysis concurrent up-regulation of OXPHOS. Benserazide hydrochloride can be used for the study of Parkinson's disease and melanoma .
loading...
    loading...
7
7 Publications Verification
Cat. No.: HY-121275
CAS No.: 322-35-0
Synonyms: Ro 4-4602
Target:  

Pyruvate Kinase

Research Areas:  

Neurological Disease Cancer

Benserazide is an aromatic L-amino acid decarboxylase (AADC) and L-DOPA decarboxylase inhibitor. Benserazide is also a PKM2 inhibitor. Benserazide directly binds to and blocks PKM2 enzyme activity, leading to inhibition of aerobic glycolysis concurrent up-regulation of OXPHOS. Benserazide can be used for the study of Parkinson's disease and melanoma .
loading...
    loading...
5
5 Cited Publications
Cat. No.: HY-W011727A
CAS No.: 41468-25-1
Synonyms: Pyridoxal phosphate monohydrate
Pyridoxal 5'-phosphate monohydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate monohydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′‐phosphate (PMP) .
loading...
    loading...
5
5 Cited Publications
Cat. No.: HY-W011727
CAS No.: 853645-22-4
Synonyms: Pyridoxal phosphate hydrate
Pyridoxal 5'-phosphate hydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate hydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-111365
CAS No.: 1883602-21-8
Purity:  98.12%
Target:  

KMO

Research Areas:  

Metabolic Disease

TES-1025 is a potent and selective human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) inhibitor with an IC50 of 13 nM .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-N0122
CAS No.: 56-69-9
Synonyms: 5-HTP; DL-5-Hydroxytryptophan
5-Hydroxytryptophan, a tryptophan metabolite, is a direct 5-hydroxytryptamine (5-HT) precursor and an L-aromatic amino acid decarboxylase substrate. .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-N0384
CAS No.: 306-08-1
Synonyms: Vanilacetic Acid
Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W012906
CAS No.: 16338-48-0
Synonyms: L-2-Allylglycine
L-Allylglycine (L-2-Allylglycine) is an amino acid derivative. L-Allylglycine is an inhibitor for glutamate decarboxylase (GAD) that reduces the GABA biosynthesis in the brain. L-Allylglycine exhibits convulsant activity .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-112619
CAS No.: 1883602-20-7
Purity:  99.34%
Research Areas:  

Metabolic Disease

TES-991 is a potent and selective human α Amino-β-carboxymuconate-ε-semialdehyde Decarboxylase (ACMSD) inhibitor, with an IC50 of 3 nM.
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W015595
CAS No.: 195316-72-4
Synonyms: L-2-Allylglycine hydrochloride
L-Allylglycine (L-2-Allylglycine) hydrochloride is an amino acid derivative. L-Allylglycine hydrochloride is an inhibitor for glutamate decarboxylase (GAD) that reduces the GABA biosynthesis in the brain. L-Allylglycine hydrochloride exhibits convulsant activity .
loading...
    loading...
Cat. No.: HY-W011727S
CAS No.: 1354560-58-9
Synonyms: Pyridoxal 5'-phosphate-d3
Pyridoxal Phosphate-d3 is the deuterium labeled Pyridoxal 5'-phosphate. Pyridoxal 5'-phosphate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .
loading...
    loading...
Cat. No.: HY-W019599
CAS No.: 14173-39-8
Synonyms: L-PCPA
4-Chloro-L-phenylalanine (L-PCPA) is a tryptophan hydroxylase inhibitor targeting TPH1 and TPH2, with the activity of blocking serotonin biosynthesis. 4-Chloro-L-phenylalanine reduces the levels of serotonin and its metabolites in the brain without impairing the survival of serotonergic neurons. 4-Chloro-L-phenylalanine enhances anhedonic, depression-like and anxiety-like behaviors in mice with depleted noradrenergic and dopaminergic neurons. 4-Chloro-L-phenylalanine acts as a decarboxylation substrate for aromatic L-amino acid decarboxylase from Bacillus atrophaeus. 4-Chloro-L-phenylalanine can be used in studies related to Parkinson's disease .
loading...
    loading...
Cat. No.: HY-113468
CAS No.: 7636-26-2
Purity:  99.94%
Synonyms: 3-Methoxytyrosine
3-O-Methyl-DL-DOPA is an endogenous metabolite present in Cerebrospinal_Fluid that can be used for the research of Epilepsy, Purine Nucleoside Phosphorylase Deficiency and Aromatic L Amino Acid Decarboxylase Deficiency .
loading...
    loading...
Cat. No.: HY-109131
CAS No.: 1907685-81-7
Purity:  95.91%
Synonyms: ABBV-951; Carbidopa 4′-monophosphate
Foscarbidopa (ABBV-951; Carbidopa 4′-monophosphate) is an inhibitory prodrug targeting peripheral aromatic L-amino acid decarboxylase. Foscarbidopa is hydrolyzed into Carbidopa (HY-B0311) by phosphatases in vivo to suppress peripheral metabolism of levodopa and elevate brain delivery of levodopa. Foscarbidopa can be used for the research of Parkinson’s disease and advanced Parkinson’s disease .
loading...
    loading...
Cat. No.: HY-W003445
CAS No.: 14348-38-0
4-Bromo-3-hydroxybenzoic acid is a metabolite of Brocresine and a histidine decarboxylase (HDC) inhibitor with IC50s of 1 mM for both rat fetal and rat gastric HDC. 4-Bromo-3-hydroxybenzoic acid also inhibits aromatic-L-amino acid decarboxylase from hog kidney and rat gastric mucosa in vitro with IC50s of 1 mM for both enzymes .
loading...
    loading...
Cat. No.: HY-N0384S2
CAS No.: 53587-32-9
Synonyms: Vanilacetic Acid-d5
Homovanillic acid-d5 (Vanilacetic acid-d5) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .
loading...
    loading...
Cat. No.: HY-N3394
CAS No.: 480-56-8
Lecanoric acid is a histidine-decarboxylase inhibitor isolated from fungus. The inhibition by lecanoric acid is competitive with histidineand noncompetitive with pyridoxal phosphate. Lecanoric acid did not inhibit aromatic amino acid decarboxylase .
loading...
    loading...
Cat. No.: HY-N0384R
CAS No.: 306-08-1
Synonyms: Vanilacetic Acid (Standard)
Homovanillic acid (Standard) (Vanilacetic acid (Standard)) is the analytical standard of Homovanillic acid (HY-N0384). This product is intended for research and analytical applications. Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .
loading...
    loading...
Cat. No.: HY-113305
CAS No.: 51317-41-0
Dopamine 3-O-sulfate mainly exists in plasma and can be used as a biomarker to characterize aromatic amino acid decarboxylase (AADC) deficiency .
loading...
    loading...
Cat. No.: HY-B0404AR
CAS No.: 14919-77-8
Synonyms: Ro 4-4602 hydrochloride (Standard)
Benserazide hydrochloride (Standard) (Serazide (Standard)) is the analytical standard of Benserazide hydrochloride (HY-B0404A). This product is intended for research and analytical applications. Benserazide hydrochloride (Serazide) is an aromatic L-amino acid decarboxylase (AADC) and L-DOPA decarboxylase inhibitor. Benserazide hydrochloride is also a PKM2 inhibitor. Benserazide hydrochloride directly binds to and blocks PKM2 enzyme activity, leading to inhibition of aerobic glycolysis concurrent up-regulation of OXPHOS. Benserazide hydrochloride can be used for the study of Parkinson's disease and melanoma .
loading...
    loading...