51 Results for "

BAFF

" in MedChemExpress (MCE) Product Catalog:
Products (51)

51 Results for "BAFF" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P700161AF
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P7003
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuBAFF/TNFSF13B; BLYS; TALL1; THANK; ZTNF4; TALL-1; TNFSF20
Species:  
Source:  
CHO
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Cat. No.: HY-P990706
CAS No.: 2490217-42-8
Synonyms: ALPN-303

Target:  

TNF Receptor

Domaines de recherche:  

Inflammation/Immunology

Povetacicept (ALPN-303) is an engineered Fc fusion protein containing the TACI domain, and acts as a dual APRIL/BAFF antagonist. The Kd value of Povetacicept for human BAFF is 59.3 pM, while its Kd value for human APRIL is 1.00 pM. Povetacicept reduces the activation, proliferation, differentiation and survival of B cells, and inhibits the production of immunoglobulins and autoantibodies. Povetacicept can be used in research related to autoimmune hemolytic anemia, immune thrombocytopenia, systemic lupus erythematosus, lupus nephritis and myasthenia gravis .
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Cat. No.: HY-P99653
CAS No.: 1929549-92-7
Synonyms: VAY-736

Target:  

TNF Receptor

Domaines de recherche:  

Cancer

Ianalumab (VAY-736) is a human, decarboxylated antibody against BAFF-R. Ianalumab can block the interaction between BAFF and BAFF-R and antagonize the apoptosis protection mediated by BAFF. Ianalumab exerts antibody-dependent cytotoxic (ADCC), depending on effector cell activation mediated by immune receptor tyrosine activation motif (ITAM) .
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Cat. No.: HY-P991490

Target:  

CD38 CD3 TNF Receptor

Domaines de recherche:  

Cancer

ISB2001 is a trispecific antibody targeting CD38, CD3 and BCMA. ISB2001 effectively counteracts tumor immune escape mechanisms caused by antigen downregulation, antigen loss, soluble factor competition and other factors. ISB2001 is applicable to relevant research on multiple myeloma and relapsed/refractory multiple myeloma .
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Cat. No.: HY-P99220
CAS No.: 1143503-67-6
Synonyms: LY2127399

Target:  

TNF Receptor

Domaines de recherche:  

Inflammation/Immunology Cancer

Tabalumab (LY2127399) is a human anti-BAFF (B-cell activating factor) monoclonal antibody (IgG4 type) with neutralising activity against membrane bound and soluble BAFF. Tabalumab can be used in studies of autoimmune diseases such as rheumatoid arthritis, renal failure and systemic lupus erythematosus .
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Cat. No.: HY-P99563
CAS No.: 1849636-24-3
Synonyms: LY 3090106

Domaines de recherche:  

Inflammation/Immunology

Tibulizumab (LY 3090106) is a tetravalent bispecific monoclonal antibody targeting B-cell activating factor (BAFF) and IL-17A with Kd values of 60 pM and 14 pM, respectively. Tibulizumab can be used for autoimmune disease research .
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Cat. No.: HY-P99653A
Synonyms: VAY-736 (FUT8-KO)

Domaines de recherche:  

Inflammation/Immunology Cancer

Ianalumab (VAY-736) (FUT8-KO) is an anti-BAFF-R monoclonal antibody expressed in CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose depletion enhances its B cell clearance capacity. Ianalumab (FUT8-KO) competitively blocks the binding of BAFF to BAFF-R, inhibits the BAFF-mediated alternative NF-κB pro-survival signaling pathway, and abrogates the apoptotic (apoptosis) protective effect of BAFF on cancer cells. Ianalumab (FUT8-KO) can be used in research related to primary Sjögren's syndrome and chronic lymphocytic leukemia .
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Cat. No.: HY-N11011
CAS No.: 57423-72-0
Withaphysalin A is a withanolide compound with anti-inflammatory and antioxidant activities. Withaphysalin A inhibits LPS (HY-D1056)-induced nuclear translocation of NF-κB p65, as well as phosphorylation of STAT3, ERK, JNK and p38 MAPK. Withaphysalin A upregulates the expression of HO-1. Withaphysalin A inhibits LPS-induced production of NO, PGE2, IL-1β, IL-6 and TNF-α. Withaphysalin A downregulates LPS-induced expression of iNOS and COX-2. Withaphysalin A interacts with B-cell activating factor protein (BAFF) to exert inhibitory effects. Withaphysalin A exhibits ELOVL6 inhibitory activity. Withaphysalin A can be used in the research of inflammatory diseases, nephrotic syndrome and chronic myeloid leukemia .
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Cat. No.: HY-P99487
CAS No.: 869881-54-9
Synonyms: BR 3FC

Target:  

ADC Antibodies

Domaines de recherche:  

Inflammation/Immunology

Briobacept (BR 3FC) is a recombinant glucoprotein, consists of 2 molecules from the BLyS receptor (BR3)and a Fc domain of human IgG1. Briobacept selectively targets to BLyS (BAFF), induces B cells apoptosis. Briobacept can be used in studies of rheumatoid arthritis (RA) .
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Cat. No.: HY-P99893
CAS No.: 2143449-47-0
Synonyms: AMG-570

Target:  

CD28 TNF Receptor

Domaines de recherche:  

Inflammation/Immunology

Rozibafusp alfa (AMG-570) is a humanized IgG2-κ monoclonal antibody targets ICOSL and BAFF. Rozibafusp alfa can be used for the research of systemic lupus erythematosus and other autoimmune diseases .
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Cat. No.: HY-RS17086
Domaines de recherche:  

Others

Tnfsf13b Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tnfsf13b gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS14824
Domaines de recherche:  

Others

TNFSF13B Human Pre-designed siRNA Set A contains three designed siRNAs for TNFSF13B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P991778

Target:  

TNF Receptor

Domaines de recherche:  

Inflammation/Immunology

Anti-Mouse BAFF-R Antibody (9B9) reacts with mouse B-cell activating factor receptor (BAFF-R). Anti-Mouse BAFF-R Antibody (9B9) blocks BAFF-R both in vivo and in vitro. Recommend Isotype Controls: Rat IgG2b kappa, Isotype Control (HY-P990682) .
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Cat. No.: HY-P700531
Pureté:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BAFF; BLyS; CD257; TNFSF13B; TNFSF20; DTL; TALL1; TALL-1delta BAFF; TALL1Delta4 BAFF; THANK; ZTNF4; TALL-1
Species:  
Source:  
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Cat. No.: HY-P75589
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor ligand superfamily member 13B; BAFF; TALL-1
Species:  
Source:  
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Cat. No.: HY-P992101
CAS No.: 3057276-00-0
Synonyms: AUR-200

Domaines de recherche:  

Inflammation/Immunology

Aritinercept (AUR-200) is a recombinant fusion protein targeting TNFSF13B/BAFF/CD257. Aritinercept neutralizes BAFF and APRIL (TNFSF13), reduces B cell proliferation, suppresses peripheral B cells, lowers serum immunoglobulins. Aritinercept reduces renal damage markers, decreases IFNγ, IL-17A, and anti-dsDNA autoantibodies, and improves survival in a mouse model of SLE. ritinercept can be used for the research of systemic lupus erythematosus .
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Cat. No.: HY-P703757
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BAFF; BLyS; CD257; TNFSF13B; TNFSF20; DTL; TALL1; TALL-1delta BAFF; TALL1Delta4 BAFF; THANK; ZTNF4; TALL-1
Species:  
Source:  
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Cat. No.: HY-P84885
Synonyms: DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNLG7A; TNFSF20

Host:  

Mouse

Application:  

WB, ICC/IF, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P78385
Pureté:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: BAFF; BLyS; CD257; TNFSF13B; TNFSF20; DTL; TALL1; TALL-1delta BAFF; TALL1Delta4 BAFF; THANK; ZTNF4; TALL-1
Species:  
Source:  
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