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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
115 Results for "
CTP
" in MedChemExpress (MCE) Product Catalog:
Products (115)
115 Results for "CTP" in MCE Product Catalog:
2
Target:
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15
15 Publications Verification
Synonyms: HePC; Hexadecyl phosphocholine
Research Areas:
Miltefosine is a broad spectrum antimicrobial, anti-leishmanial, phospholipid agent acting by inhibiting the PI3K/Akt activity . Miltefosine is an inhibitor of CTP-phosphocholine cytidyltransferase (CCT) .
3
3 Cited Publications
Synonyms: Cytidine triphosphate; 5'-CTP
Category:
Infection Human Gut Microbiota Metabolites Natural Products Endogenous metabolite Disease Research Fields Cancer
Target:
3
3 Cited Publications
Cat. No.: HY-W013100
CAS No.: 36051-68-0
Synonyms: Cytidine triphosphate disodium; 5'-CTP disodium
Research Areas:
Cytidine-5'-triphosphate (Cytidine triphosphate; 5'-CTP) disodium is a nucleoside triphosphate, that is invovled in biosynthesis of DNA, RNA and lipid. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate disodium is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii .
3
3 Cited Publications
Cat. No.: HY-W013707
CAS No.: 81012-87-5
Synonyms: Cytidine triphosphate disodium dihydrate; 5'-CTP disodium dihydrate
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Cytidine-5'-triphosphate disodium dihydrate (Cytidine triphosphate disodium dihydrate) is a nucleoside triphosphate and a substrate of CMP-KDO synthase, forming CMP-KDO. Cytidine-5'-triphosphate disodium dihydrate is a precursor of RNA/DNA, phospholipids, and sialoglycoproteins, is reduced to dCTP by deoxycytidylate-generating reductase, and can be used for the biosynthesis of phosphatidic acid to CDP-DG/cardiolipin .
1
1 Cited Publications
Synonyms: ac4CTP sodium solution (100mM)
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N4-Acetylcytidine triphosphate sodium solution (100mM) is efficiently used as a substrate in T7 Polymerase-catalyzed in vitro
transcription and it can be incorporated into multiple templates .
The product specifications provided below indicate the total amount only; they do not represent the actual content of N4-Acetylcytidine triphosphate sodium.
The product specifications provided below indicate the total amount only; they do not represent the actual content of N4-Acetylcytidine triphosphate sodium.
1
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Dencatistat (STP938) is a selective and orally active CTPS1 inhibitor (IC50 = 9.3 nM) that reduces the rate-limiting conversion of UTP to CTP. Dencatistat exhibits more than 1300-fold selectivity for CTPS2. Dencatistat modulates BCL2 family transcripts and cell cycle pathways, and inhibits SARS-CoV-2 replication and interferon-induced Mx expression. Dencatistat has antiproliferative and tumor growth-inhibiting effects in mantle cell lymphoma models. Dencatistat inhibits clonogenic growth, migration, invasion, and xenograft tumor growth in lung adenocarcinoma, with tumor selectivity over normal bronchial epithelial cells. Dencatistat can be used for research on COVID-19, mantle cell lymphoma, essential thrombocythemia, and lung adenocarcinoma .
1
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5-Methylcytidine 5′-triphosphate trisodium (5-Methyl-CTP trisodium) is a modified cytidine triphosphate nucleotide. 5-Methylcytidine 5′-triphosphate trisodium serves as a modified nucleotide substrate for in vitro transcription, partially or completely replacing CTP. 5-Methylcytidine 5′-triphosphate trisodium enhances mRNA stability and translation efficiency, and reduces activation of the innate immune system. 5-Methylcytidine 5′-triphosphate trisodium is used in RNA synthesis-related research .
The product specifications provided below refer solely to the active content of 5-Methylcytidine 5′-triphosphate trisodium.
The product specifications provided below refer solely to the active content of 5-Methylcytidine 5′-triphosphate trisodium.
1
1 Cited Publications
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CTPS1-IN-1 (compound R80) is a CTPS1 inhibitor. CTPS1-IN-1 has the potential to research cancer (such as promoting vascular injury or surgical recovery) and immune system diseases (such as rejection of transplanted cells and tissues, transplant-related diseases or disorders, allergies, and autoimmune diseases) .
1
1 Cited Publications
Synonyms: CPEC; NSC 375575
Cyclopentenylcytosine (CPEC), a carbocyclic nucleoside analog of cytosine, is a potent inhibitor of CTP synthetase and causes depletion of CTP and dCTP pools. Cyclopentenylcytosine shows broad-spectrum (both DNA and RNA viruses) antiviral activity. Cyclopentenyl cytosine increases Gemcitabine (HY-17026) radiosensitisation in human pancreatic cancer cells. Cyclopentenylcytosine shows effective antiviral activity in the Ad5/NZW rabbit ocular replication model and shows anti-tumor activity in various tumor xenografts model. Cyclopentenylcytosine can be used for the study of infection and cancer .
1
1 Cited Publications
Target:
Cyclopentenyl uracil is a non-cytotoxic Uridine-Cytidine Kinase inhibitor and an antagonist of EIDD-1931 (NHC) (HY-125033) bioactivation. Cyclopentenyl uracil blocks NHC phosphorylation by inhibiting UCK1/UCK2, reduces intracellular NHC-TP accumulation, and depletes UTP/CTP pools, thereby antagonizing the antiviral activity of NHC and inhibiting dengue virus replication. Cyclopentenyl uracil is used in research on SARS-CoV-2 infection, dengue virus infection, leukemia, and solid tumors .
1
1 Cited Publications
Cat. No.: HY-128788A
Research Areas:
ddhCTP trisodium solution (100 mM ± 3 mM) is an endogenously produced pyrimidine base analog with a Kd of 17.0 nM for LLDH and an IC50 of 55.8 μM for GAPDH. By inhibiting key metabolic enzymes such as GAPDH, ddhCTP trisodium reduces glycolytic flux and shifts metabolic flow toward the pentose phosphate pathway, thereby regulating the redox balance of cells. As a competitive CTP analog, ddhCTP trisodium terminates RNA synthesis by flavivirus RdRps and SARS-CoV-2 RdRp, and inhibits Zika virus replication in vivo. ddhCTP trisodium can be used in studies related to viral infections, COVID-19 and Zika virus infections .
The product specifications provided below indicate the total amount only; they do not represent the actual content of ddhCTP trisodium.
The product specifications provided below indicate the total amount only; they do not represent the actual content of ddhCTP trisodium.
Cat. No.: HY-50856S
CAS No.: 1513883-39-0
Synonyms: CTP-543; Ruxolitinib-d8; INCB18424-d8
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Deuruxolitinib (CTP-543; Ruxolitinib-d8) is a deuterated analog of Ruxolitinib (HY-50856) and an orally active, selective inhibitor of JAK1 and JAK2. Deuruxolitinib blocks Janus kinase-mediated cytokine receptor signaling and proinflammatory cytokine gene expression. Deuruxolitinib is primarily metabolized in the liver via CYP2C9. Deuruxolitinib promotes scalp hair regrowth in severe chronic alopecia areata. Deuruxolitinib is used in alopecia areata-related research .
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CTP Synthetase-IN-1 is a potent, orally active cytidine 5'-triphosphate synthetase (CTPS) inhibitor with IC50s of 32 nM and 18 nM for human CTPS1 and human CTPS2, respectively. CTP Synthetase-IN-1 has anti-inflammatory effects .
Cat. No.: HY-W008915
CAS No.: 34393-59-4
Synonyms: CDP
Category:
Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-P99750
CAS No.: 1443004-16-7
Synonyms: CT-P23
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Cat. No.: HY-125818I
CAS No.: 36051-68-0
Synonyms: Cytidine triphosphate disodium salt, 100 mM Solution, PCR Grade; 5'-CTP disodium salt, 100 mM Solution, PCR Grade
Target:
Research Areas:
CTP (Cytidine triphosphate; 5'-CTP disodium salt) disodium salt, 100 mM Solution, PCR Grade is an immediate-use solution of cytidine triphosphate diodium salt. CTP is one of the four basic raw materials for RNA biosynthesis. CTP disodium salt is mainly used in molecular biology applications such as in vitro transcription (IVT), RNA synthesis and labeling .
The product specifications provided below indicate the total amount only; they do not represent the actual content of CTP disodium salt.
The product specifications provided below indicate the total amount only; they do not represent the actual content of CTP disodium salt.
Target:
Research Areas:
CTP inhibitor (Compound 792949) is a potent and selective CTP inhibitor. CTP inhibitor inhibits the plasma membrane citrate transporter (PMCT) .
Cat. No.: HY-P99620
CAS No.: 1443004-15-6
Synonyms: CT-P22; CT120
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Cat. No.: HY-P99346
CAS No.: 2444308-95-4
Synonyms: CT-P59
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
