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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
287 Results for "
Crumbs3 transcript
" in MedChemExpress (MCE) Product Catalog:
Products (287)
287 Results for "Crumbs3 transcript" in MCE Product Catalog:
7
7 Publications Verification
CWI1-2 is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts, induces apoptosis and differentiation, and shows promising anti-leukemic effects .
7
7 Publications Verification
CWI1-2 hydrochloride is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts, induces apoptosis and differentiation, and shows promising anti-leukemic effects .
7
7 Publications Verification
Synonyms: RG 7128; R-7128; PSI 6130 diisobutyrate
Mericitabine (RG 7128; R-7128) is a nucleoside inhibitor of the HCV NS5B polymerase that acts as an RNA chain terminator and prevents elongation of RNA transcripts during replication.
3
3 Cited Publications
Research Areas:
FHD-609 is a BRD9 PROTAC degrader. FHD-609 induces BRD9 degradation, downregulates primary transcripts of HBG/HBD, Myc expression and proliferation gene sets, reduces the levels of synovial sarcoma tumor proliferation markers, and inhibits tumor growth. FHD-609 can be used in research related to advanced synovial sarcoma, SMARCB1-deficient tumors and adrenocortical carcinoma [3] .
3
3 Cited Publications
Target:
Research Areas:
MALAT1-IN-1 (compounds 5) is a potent and specific Malat1 (Metastasis-associated lung adenocarcinoma transcript 1) inhibitor. MALAT1-IN-1 modulated Malat1 downstream genes in a dose-dependent manner without affecting expression of nuclear enriched abundant transcript 1 (Neat1) .
2
2 Cited Publications
Cat. No.: HY-161111
CAS No.: 3056394-59-0
Target:
Research Areas:
KVS0001 is a selective SMG1 inhibitor. KVS0001 elevates the expression of transcripts and proteins resulting from truncating mutations. KVS0001 increased the presentation of immune-targetable HLA class I-associated peptides from nonsense-mediated decay (NMD)-downregulated proteins on the surface of cancer cells. KVS0001 exerts anti-tumor properties and can be studied in research for NMD-related diseases, including cancer and inherited diseases .
2
2 Cited Publications
Cat. No.: HY-P70004
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD36; Leukocyte Differentiation Antigen CD36; CD36 Molecule (CD36 Blood Group); Thrombospondin Receptor; Platelet Glycoprotein 4; CD36 Antigen; GPIIIB; PAS-4; GPIV; CD36 Molecule (CD36 Blood Group) transcript; GP3B; Scavenger Receptor Class B, Member 3; F
Species:
Human
Source:
HEK293
1
Target:
Research Areas:
Ulefnersen (ION363) is an Antisense Oligonucleotide (ASO) directed against the 6th intron of the fused-in sarcoma (FUS) transcript to silence FUS in a non-allele-specific manner. Ulefnersen can reduce postnatal levels of FUS protein in the brain and spinal cord in disease-relevant mouse model of ALS-FUS , delaying motor neuron degeneration. Ulefnersen can be used in the research of Amyotrophic Lateral Sclerosis (ALS) .
1
Research Areas:
Tadnersen (BIIB078), an antisense oligonucleotide (ASO), selectively targets C9ORF72 transcript variants 1 and 3 that carry the expansion .
1
1 Cited Publications
Target:
Research Areas:
OSMI-2 (Compound 1b) is a cell-permeable O-linked N-acetylglucosamine transferase (OGT) inhibitor. Cells contain a large nuclear pool of partially spliced OGT transcript, and OSMI-2 increases detained intron splicing in cells .
1
1 Cited Publications
Synonyms: ION-363 sodium
Target:
Research Areas:
Ulefnersen sodium (ION363) is an Antisense Oligonucleotide (ASO) directed against the 6th intron of the fused-in sarcoma (FUS) transcript to silence FUS in a non-allele-specific manner. Ulefnersen sodium can reduce postnatal levels of FUS protein in the brain and spinal cord in disease-relevant mouse model of ALS-FUS , delaying motor neuron degeneration. Ulefnersen sodium can be used in the research of Amyotrophic Lateral Sclerosis (ALS) .
1
1 Cited Publications
Cat. No.: HY-132581A
Purity: 90.06%
Synonyms: BIIB078 sodium; IONIS-C9Rx sodium
Target:
Research Areas:
Tadnersen sodium, an antisense oligonucleotide (ASO), selectively targets C9ORF72 transcript variants 1 and 3 that carry the expansion .
1
1 Cited Publications
Cat. No.: HY-P70573A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IRF5; Interferon Regulatory Factor 5 transcript Variant 15; Interferon Regulatory Factor 5; Interferon Regulatory Factor 5 transcript Variant 17; IRF-5; Interferon Regulatory Factor 5 Variant 7; Interferon Regulatory Factor 5 transcript Variant 16; Interf
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P70890
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FAM3D; Oncoprotein-Induced transcript 1; FAM3 Metabolism Regulating Signaling Molecule D; Protein FAM3D; OIT1; Family With Sequence Similarity 3, Member D; EF7; Cytokine-Like Protein EF-7; Family With Sequence Similarity 3 Member D
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P71590
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KLK14; Kallikrein-Related Peptidase 14 transcript Variant 2; Kallikrein Related Peptidase 14; Kallikrein-Related Peptidase 14 transcript Variant 3; KLK-L6; Kallikrein 14; Kallikrein-Like Protein 6; KLKL6; Kallikrein-14; HK14
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P85890
Synonyms: AIF 1; AIF-1; Aif1; AIF1 protein; AIF1_HUMAN; Allograft inflammatory factor 1; Allograft inflammatory factor 1 splice variant G; allograft inflammatory factor-1 splice variant Hara-1; balloon angioplasty responsive transcription; BART 1; G1; G1 putative splice variant of allograft inflamatory factor 1; IBA 1; IBA1; interferon gamma responsive transcript; Interferon responsive transcript 1; interferon responsive transcript factor 1; Ionized calcium binding adapter molecule 1; Ionized calcium-binding adapter molecule 1; ionized calcium-binding adapter molecule; IRT 1; IRT1; Microglia response factor; MRF1; Protein g1;
1
1 Cited Publications
Cat. No.: HY-P70101
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CLEC7A; CDNA FLJ59887, Moderately Similar To Homo Sapiens C-Type Lectin Domain Family 7, Member A (CLEC7A), transcript Variant 4, MRNA; Prev. CLECSF12; C-Type Lectin Domain Containing 7A transcript Variant 7; C-Type Lectin Domain Family 7 Member A; C-Type
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P702631
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: AKT1; Protein Kinase B; AKT Serine/Threonine Kinase 1; PKB Alpha; RAC; V-Akt Murine Thymoma Viral Oncogene-Like Protein 1 Isoform 2; PKB; V-Akt Murine Thymoma Viral Oncogene-Like Protein 1; RAC-Alpha Serine/Threonine-Protein Kinase; Non-Specific Serine/Threonine Protein Kinase; RAC-PK-Alpha; AKT1m transcript Variant 3; RAC-Alpha; AKT1m transcript Variant 4; PRKBA; AKT1m transcript Variant 2; AKT; AKT1m transcript Variant 1; V-Akt Murine Thymoma Viral Oncogene Homolog 1; Rac Protein Kinase Alpha; Serine-Threonine Protein Kinase; PKB-ALPHA; Protein Kinase B Alpha; AKT1m; Proto-Oncogene C-Akt
Species:
Human
Source:
Sf9 insect cells
1
1 Cited Publications
Cat. No.: HY-P81233
Synonyms: GADD153; CHOP; Growth arrest and DNA damage-inducible 153; C/EBP homologous protein; C/EBP Homology Protein; CEBPZ; CHOP10; DDIT 3; DNA Damage Inducible transcript 3; GADD 153; Growth Arrest and DNA Damage Inducible Protein 153; Growth arrest and DNA damage inducible protein GADD153; MGC4154; DDIT3_HUMAN.
1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
