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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
80 Results for "
Cyclooxygenase-2 inhibitors
" in MedChemExpress (MCE) Product Catalog:
Products (80)
80 Results for "Cyclooxygenase-2 inhibitors" in MCE Product Catalog:
76
76 Publications Verification
Synonyms: Paracetamol; 4-Acetamidophenol; 4'-Hydroxyacetanilide
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21 Cited Publications
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NS-398 is a non-steroidal an-inflammatory agent with analgesic and antipyretic effects, and selectively inhibits prostaglandin G/H synthase 2/cyclooxygenase 2 (COX-2) activity, with an IC50 of 3.8 μM, and has no effect on COX-1 at 100 μM.
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19
19 Cited Publications
Synonyms: 3,4,5-Trihydroxybenzoic acid hydrate
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16
16 Cited Publications
Synonyms: Salicylic acid sodium salt; 2-Hydroxybenzoic acid sodium salt
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1
1 Cited Publications
Synonyms: Diphosphofructose; Esafosfan; FDP
Category:
Cardiovascular Disease Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields
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1
1 Cited Publications
Synonyms: Paracetamol (Standard); 4-Acetamidophenol (Standard); 4'-Hydroxyacetanilide (Standard)
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Acetaminophen (Standard) is the analytical standard of Acetaminophen. This product is intended for research and analytical applications. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent . Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor .
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1 Cited Publications
Cat. No.: HY-N0074
CAS No.: 26091-79-2
Category:
Coumarins Phenylpropanoids Plants Umbelliferae Helogyne apaloidea Nutt. Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-66005S
CAS No.: 64315-36-2
Synonyms: Paracetamol-d4; 4-Acetamidophenol-d4; 4'-Hydroxyacetanilide-d4
Cat. No.: HY-N6084
CAS No.: 26472-41-3
Synonyms: α-Lupulic acid
Category:
Cardiovascular Disease Humulus lupulus L. Ketones, Aldehydes, Acids Plants Moraceae Disease Research Fields
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Synonyms: Lucidenic acid D2
Category:
Cardiovascular Disease Triterpenes Terpenoids Polyporaceae Ganoderma lucidum (Leyss. Ex Fr.) Karst. Plants Disease Research Fields Inflammation/Immunology
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Synonyms: BAP-909
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Imrecoxib (BAP-909) is a novel and selective cyclooxygenase 2 (COX-2) inhibitor with an IC50 value of 18 nM, it also inhibits COX1- activity with an IC50 value of 115 nM. Imrecoxib (BAP-909) has anti-inflammatory effect .
Cat. No.: HY-N0523S
CAS No.: 294660-92-7
Synonyms: 3,4,5-Trihydroxybenzoic acid-d2
Synonyms: Ind-Cl
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Research Areas:
Indazole-Cl (Ind-Cl) is an Estrogen receptor (ER)-β-specific agonist with inflammatory effect. Indazole-Cl inhibits cyclooxygenase-2 exression reduction induced by hypoxia. And Indazole-Cl inhibits ROS production. Indazole-Cl also inhibits cell migration and invasion by hypoxia increased by hypoxia. Indazole-Cl is potent inhibitor of hypoxia-induced inflammation in vascular smooth muscle cells (VSMCs) .
Research Areas:
CAY10404 is a potent and selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 1 nM and a selectivity index (SI; COX-1 IC50/COX-2 IC50) of >500000. CAY10404 is a potent PKB/Akt and MAPK signaling pathways inhibitor and induces apoptosis in non-small cell lung cancer (NSCLC) cells. CAY10404, a diarylisoxazole, has good analgesic, anti-inflammatory, and anti-cancer activities .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
