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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
45 Results for "
GPC3
" in MedChemExpress (MCE) Product Catalog:
Products (45)
45 Results for "GPC3" in MCE Product Catalog:
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MC-GGFG-AM-(10Me-11F-Camptothecin) is a linker-payload conjugate used to synthesize ZW251. ZW251 an antibody-drug conjugate (ADC) targeting human GPC3. ZW251 consists of a humanized IgG1 antibody conjugated to a novel camptothecin-based topoisomerase 1 inhibitor, ZD06519, via a linker. The linker is the maleimide anchor and a glycyl glycyl phenylalanyl glycine (GGFG)-aminomethyl (AM) cleavable linker. ZW251 has high affinity with human and cynomolgus monkey GPC3. ZW251 displays rapid internalization in GPC3-expressing HCC cell lines, and bystander-mediated killing of GPC3 negative cancer cells .
Cat. No.: HY-W1124925
CAS No.: 3066439-94-6
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Cat. No.: HY-P10888A
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Cat. No.: HY-P990841
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Cat. No.: HY-P10888
CAS No.: 3066113-41-2
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Cat. No.: HY-P990840
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Cat. No.: HY-RS05628
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GPC3 Human Pre-designed siRNA Set A contains three designed siRNAs for GPC3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16630
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Gpc3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gpc3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P991448
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Cat. No.: HY-RS23065
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Gpc3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Gpc3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P11618
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Cat. No.: HY-P992457
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Cat. No.: HY-182099
Cat. No.: HY-182099A
Cat. No.: HY-182099B
Cat. No.: HY-182099C
Cat. No.: HY-185742
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ZW-251 is a glypican-3 (GPC3)-targeted antibody-drug conjugate (ADC) with topoisomerase-I inhibitory activity. ZW-251 induces cytotoxicity, penetrates tumor spheroids, exerts bystander cytotoxicity, and inhibits tumor growth in hepatocellular carcinoma models. ZW-251 can be used for the research of hepatocellular carcinoma .
Cat. No.: HY-P992011
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
