50 Results for "

I(1,4,5)P3

" in MedChemExpress (MCE) Product Catalog:
Products (50)

50 Results for "I(1,4,5)P3" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-107588
CAS No.: 916734-43-5
Purity:  99.94%
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

TC-I 15 (TC-I-15) is a type of allosteric collagen-binding integrin α2β1 inhibitor, and it also inhibits α1β1 and α11β1. TC-I 15 inhibits platelet adhesion to collagen and thrombus deposition. TC-I 15 prevents the formation of a pre-metastatic microenvironment by inhibiting the uptake of cancer-associated fibroblast (CAF) extracellular vesicles (EVs) by lung fibroblasts, which reduces the metastasis of salivary gland adenocystic carcinoma (SACC) to the lungs in mouse models, .
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3
3 Cited Publications
Cat. No.: HY-N1939
CAS No.: 56725-99-6
Synonyms: Icarisid I
Icariside I (GH01) is an orally active metabolite of icalin. Icariside I improves estrogen deficiency-induced osteoporosis by simultaneously regulating osteoblast and osteoclast differentiation. Icariside I promotes ATP (HY-B2176) or Nigericin (HY-127019)-induced mtROS production and NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity. Icariside I does not alter the activation of NLRC4 and AIM2 inflammasomes. Icariside I inhibits breast cancer proliferation, apoptosis, invasion, and metastasis by targeting the IL-6/STAT3 pathway. Icariside I is a kynurenine-AhR pathway inhibitor that alleviates cancer by blocking tumor immune escape [3] .
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3
3 Cited Publications
Cat. No.: HY-B0175
CAS No.: 69004-03-1
Synonyms: BAY-i 9142
Target:  

Parasite Antibiotic

Research Areas:  

Infection

Toltrazuril (BAY-i 9142) is an antiprotozoal agent that acts upon Coccidia parasites.
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2
2 Cited Publications
Cat. No.: HY-N0887
CAS No.: 84676-88-0
Synonyms: Isoastragaloside-I
Isoastragaloside I is a natural compound found in Astragalus membranaceus, with oral activity and multiple biological activities such as anti-inflammatory and antioxidant properties. Isoastragaloside I inhibits Akt, NF-κB, MAPKs and PI3K, enhances the activity of hepatic FXR, regulates the TGF-β/Smads signaling pathway, and upregulates antioxidant molecules downstream of Nrf2. Isoastragaloside I inhibits the expression of NO, TNF-α, iNOS, COX-2, IL-1β and VCAM-1, and reduces intracellular ROS levels. Isoastragaloside I attenuates blood-brain barrier disruption, restores intestinal barrier function, increases β-cell mass, improves glucose homeostasis, and elevates circulating adiponectin levels. Isoastragaloside I can be used for the study of neuroinflammation-related neurodegenerative diseases, cholestatic liver disease, and diabetes [3] .
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1
1 Cited Publications
Cat. No.: HY-D0983
CAS No.: 574-64-1
Synonyms: C.I. 22850
Trypan red is a vital stain.
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1
1 Cited Publications
Cat. No.: HY-135680
CAS No.: 1094048-77-7
Purity:  98.03%
Synonyms: I-OMe-AG 538
Target:  

IGF-1R

Research Areas:  

Metabolic Disease Cancer

I-OMe-Tyrphostin AG 538 (I-OMe-AG 538) is a specific inhibitor of IGF-1R (insulin-like growth factor-1 receptor tyrosine kinase). I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and is preferentially cytotoxic to nutrient-deprived PANC1 cells.?I-OMe-Tyrphostin AG 538 is an ATP-competitive inhibitor of phosphatidylinositol-5-phosphate 4-kinase α (PI5P4Kα), with an IC50?of 1 μM .
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Cat. No.: HY-131577A
CAS No.: 42613-33-2
Synonyms: Dispase I
Target:  

Collagen

Research Areas:  

Others

Neutral protease I (Dispase I) is a rapid, effective, gentle and neutral protease that can separate intact epidermis from the dermis. Neutral protease I can also separate intact epithelial sheets in culture from the substratum. Neutral protease I preserves the viability of the epithelial cells while cleaving the basement membrane zone region. Neutral protease I can also be used to prevent clumping in suspension cultures. Neutral protease I cleaves fibronectin and type IV collagen, but not laminin, type V collagen, serum albumin, or transferrin .
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Cat. No.: HY-W019806
CAS No.: 7578-25-8
Synonyms: LNFP I
Lacto-N-fucopentaose I (LNFPI) is a human milk oligosaccharide (HMO), possessing antiviral and antibacterial activity. Lacto-N-fucopentaose I can reduce capsid protein VP1 to block virus adsorption, promote CDK2 and reduce cyclin E to recover cell cycle S phase block. Lacto-N-fucopentaose I inhibits ROS production and apoptosis in virus-infected cells. Lacto-N-fucopentaose I can also regulate intestinal microbiota to affect immune system development .
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Cat. No.: HY-110199
CAS No.: 1221349-53-6
Purity:  ≥99.0%
Target:  

TRP Channel

Research Areas:  

Neurological Disease

TC-I 2014 (compound 5) is a potent and orally active Benzimidazole-containing transient receptor potential melastatin 8 (TRPM8) antagonist, with IC50 values of 0.8 nM, 3.0 nM and 4.4 nM for canine, human and rat channels respectively. TC-I 2014 exhibits antiallodynic properties in pain models .
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Cat. No.: HY-N6724
CAS No.: 56258-32-3
Synonyms: Dihydroalterperylenol; ATX-I
Altertoxin I (Dihydroalterperylenol; ATX-I) is a quinone mycotoxin with immunosuppressive, mutagenic and anticancer activities. Altertoxin I inhibits LPS (HY-D1056)-mediated NF-κB activation and estrogen-dependent alkaline phosphatase activity. Altertoxin I activates the AhR signaling pathway, induces the expression of CYP 1A1/1A2/1B1 and the enzymatic activity of EROD. Altertoxin I can be used in breast cancer research [3].
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Cat. No.: HY-P4909
CAS No.: 200010-29-3
Synonyms: AIP-I
Target:  

Bacterial

Research Areas:  

Infection

Autoinducing Peptide I (AIP-I) is a competitive AgrC antagonist and AgrC I activator. By blocking AIP-AgrC interaction and agr quorum sensing signaling, it inhibits MRSA agr-I and agr-III and protects the mouse skin barrier. Autoinducing Peptide I can be used in research on Staphylococcus aureus infection [3] .
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Cat. No.: HY-NP0190
Synonyms: UEA I (Biotinylated)
Ulex Europaeus Agglutinin I Biotinylated (UEA I Biotinylated) is a biotinylated lectin that binds to α1,2-fucosylated proteins and cell-surface glycoconjugates containing α-L-fucose. Ulex Europaeus Agglutinin I Biotinylated serves as a histochemical marker for endothelial cells .
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Cat. No.: HY-NP079
Synonyms: RCA I
Ricinus Communis Agglutinin I (RCA I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ricinus Communis Agglutinin I (RCA I) is a biological material or organic compound that can be used in life science research .
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Cat. No.: HY-NP068
Synonyms: GSL I
Griffonia (Bandeiraea) Simplicifolia Lectin I (GSL I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Griffonia (Bandeiraea) Simplicifolia Lectin I (GSL I) is a biological material or organic compound that can be used in life science research .
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Cat. No.: HY-P2774
CAS No.: 9033-12-9
Synonyms: Glo-I
Target:  

Glycosidase

Research Areas:  

Inflammation/Immunology Cancer

Glyoxalase I (Glo-I) is a glycosidase and a methylglyoxal (MOG) detoxification enzyme. Glyoxalase I can be used for the research of inflammation and cancer .
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Cat. No.: HY-P3055A
Synonyms: DTX-I TFA
Target:  

Potassium Channel

Research Areas:  

Cancer

Dendrotoxin-I (DTX-I) TFA is a potent K + channel blocker with IC50s of 0.13-50 nM for voltage-gated potassium channel subunits KV1.1, KV1.2 and KV1.6. Dendrotoxin-I TFA, a neurotoxin, has the potential for cancer research [3].
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Cat. No.: HY-NP072
Synonyms: MAL I
Maackia Amurensis Lectin I (MAL I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Maackia Amurensis Lectin I (MAL I) is a biological material or organic compound that can be used in life science research .
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Cat. No.: HY-NP0186
Synonyms: RCA I (Biotinylated)
Ricinus Communis Agglutinin I (Biotinylated) (RCA I (Biotinylated)) is a lectin and histochemical stain that binds to glycosylated residues of laminin A, B, and M chains. Ricinus Communis Agglutinin I (Biotinylated) acts as a sensitive probe for the localization of laminin heavy chains, and can also be used to purify laminin from skeletal muscle via lectin affinity chromatography. Ricinus Communis Agglutinin I (Biotinylated) is applicable to studies of intracerebrally transplanted tumors [3].
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Cat. No.: HY-NP150
Synonyms: MAL I (Biotinylated)
Maackia Amurensis Lectin I Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.). Maackia Amurensis Lectin I Biotinylated is a biological material or organic compound that can be used in life science research .
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Cat. No.: HY-NP0145
Synonyms: UEA I (Fluorescein)
Ulex Europaeus Agglutinin I (UEA I) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ulex Europaeus Agglutinin I (UEA I) Fluorescein is a biological material or organic compound that can be used in life science research .
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