513 Results for "

Naturally

" in MedChemExpress (MCE) Product Catalog:
Products (513)

513 Results for "Naturally" in MCE Product Catalog:

388
388 Publications Verification
Cat. No.: HY-B0015
CAS No.: 33069-62-4
Paclitaxel is a naturally occurring antineoplastic agent and stabilizes tubulin polymerization. Paclitaxel can cause both mitotic arrest and apoptotic cell death. Paclitaxel also induces autophagy .
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61
61 Cited Publications
Cat. No.: HY-B0389
CAS No.: 50-99-7
Synonyms: Glucose; D-(+)-Glucose; Dextrose
D-Glucose is the naturally occurring form of glucose and the most abundant monosaccharide. D-Glucose is a critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic or abiotic stress response .
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27
27 Cited Publications
Cat. No.: HY-15398
CAS No.: 67-97-0
Purity:  99.94%
Synonyms: Cholecalciferol; Colecalciferol
Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.
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26
26 Cited Publications
Cat. No.: HY-13518
CAS No.: 10083-24-6
Purity:  98.97%
Synonyms: Astringenin; trans-Piceatannol
Piceatannol is a well-known Syk inhibitor and reduces the expression of iNOS induced by TNF. Piceatannol is an effective agent for research of acute lung injury (ALI) . Piceatannol is a naturally occurring polyphenolic stilbene found in various fruits and vegetables and exhibits anticancer and anti-inflammatory properties . Piceatannol induces apoptosis in DLBCL cell lines . Piceatannol induces autophagy and apoptosis in MOLT-4 human leukemia cells .
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25
25 Cited Publications
Cat. No.: HY-N0400
CAS No.: 632-85-9
Wogonin is a naturally occurring mono-flavonoid, can inhibit the activity of CDK8 and Wnt, and exhibits anti-inflammatory and anti-tumor effects.
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22
22 Cited Publications
Cat. No.: HY-N0683
CAS No.: 59-02-9
Synonyms: (+)-α-Tocopherol; D-α-Tocopherol
α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant .
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19
19 Cited Publications
Cat. No.: HY-N0287
CAS No.: 502-65-8
Lycopene is naturally occurring carotenoids found in tomato, tomato products, and in other red fruits and vegetables; exhibits antioxidant effects.
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18
18 Cited Publications
Cat. No.: HY-N2148
CAS No.: 321661-62-5
Synonyms: Csn-B; Dothiorelone G
Cytosporone B (Csn-B; Dothiorelone G) is a naturally occurring nuclear orphan receptor Nur77/NR4A1 agonist with an EC50 of 0.278 nM.
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17
17 Cited Publications
Cat. No.: HY-14595
CAS No.: 491-80-5
Purity:  99.29%
Synonyms: 4-Methylgenistein; Olmelin
Biochanin A is a naturally occurring fatty acid amide hydrolase (FAAH) inhibitor, which inhibits FAAH with IC50s of 1.8, 1.4 and 2.4 μM for mouse, rat, and human FAAH, respectively.
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15
15 Cited Publications
Cat. No.: HY-13425
CAS No.: 522-17-8
Purity:  99.20%
Synonyms: (-)-Deguelin; (-)-cis-Deguelin
Deguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-κB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1α, COX-2, and NF-κB.
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14
14 Cited Publications
Cat. No.: HY-13555
CAS No.: 4707-32-8
Purity:  99.93%
Synonyms: ARQ-501; NSC-26326
β-Lapachone (ARQ-501;NSC-26326) is a naturally occurring O-naphthoquinone, acts as a topoisomerase I inhibitor, and induces apoptosis by inhibiting cell cycle progression.
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14
14 Cited Publications
Cat. No.: HY-N6979
CAS No.: 5289-74-7
Synonyms: 20-Hydroxyecdysone
Crustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Serratula coronata which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP . Crustecdysone exhibits regulatory or protective roles in the cardiovascular system . Crustecdysone is an active metabolite of Ecdysone (HY-N0179) .
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11
11 Cited Publications
Cat. No.: HY-B1000
CAS No.: 1464-42-2
Synonyms: Seleno-DL-methionine; DL-Selenomethionine
Selenomethionine is a naturally occurring amino acid containing selenium that has oral activity and is a common natural food source. Selenomethionine has antitumor activity .
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11
11 Cited Publications
Cat. No.: HY-N0116
CAS No.: 517-28-2
Synonyms: Natural Black 1; Haematoxylin
Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from Caesalpinia sappan Linn.. Hematoxylin is a nuclear stain in histology and is also a potent Aβ42 fibrillogenesis inhibitor with an IC50 of 1.6 μM.
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10
10 Cited Publications
Cat. No.: HY-N0057
CAS No.: 14534-61-3
Synonyms: 3,4-Di-O-caffeoylquinic acid; Isochlorogenic acid B
3,4-Dicaffeoylquinic acid (3,4-Di-O-caffeoylquinic acid), naturally isolated from Laggera alata, has antioxidative, DNA protective, neuroprotective and hepatoprotective properties. 3,4-Dicaffeoylquinic acid exerts apoptosis-mediated cytotoxicity and α-glucosidase inhibitory effects. 3,4-Dicaffeoylquinic acid possesses a unique mechanism of anti-influenza viral activity, that is, enhancing viral clearance by increasing TRAIL .
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10
10 Cited Publications
Cat. No.: HY-A0256
CAS No.: 58001-44-8
Clavulanic acid is a naturally occurring powerful bacterial β-lactamases inhibitor for research of infections caused by bacteria, including infections of the ears. Clavulanic acid is active against a wide spectrum of gram-positive and gram-negative bacterias .
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9
9 Cited Publications
Cat. No.: HY-P0027
CAS No.: 102396-24-7
Jasplakinolide is a potent actin polymerization inducer and stabilizes pre-existing actin filaments. Jasplakinolide binds to F-actin competitively with phalloidin with a Kd of 15 nM. Jasplakinolide, a naturally occurring cyclic peptide from the marine sponge, has both fungicidal and anti-cancer activity .
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8
8 Cited Publications
Cat. No.: HY-N0684
CAS No.: 84-80-0
Synonyms: Phylloquinone; Phytomenadione
Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.
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8
8 Cited Publications
Cat. No.: HY-N0453
CAS No.: 548-04-9
Hypericin is a naturally occurring substance found in Hyperlcurn perforatum L. Hypericin is an inhibitor of PKC (protein kinase C), MAO (monoaminoxidase), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450). Hypericin shows antitumor, antiviral, antidepressive activities, and can induce apoptosis .
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8
8 Cited Publications
Cat. No.: HY-N1445
CAS No.: 482-35-9
Synonyms: Isoquercetin; Quercetin 3-glucoside
Isoquercetin (Quercetin 3-glucoside) is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties. Isoquercetin alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway . Isoquercetin regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system. Isoquercetin has high bioavailability and low toxicity, is a promising candidate agent to prevent birth defects in diabetic pregnancies .
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