1 Result for "

P4-R5 MAGI cells

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "P4-R5 MAGI cells" in MCE Product Catalog:

Cat. No.: HY-103078
CAS No.: 5496-35-5
Purity:  99.71%
Research Areas:  

Infection

I-XW-053 is a specific anti-HIV-1 capsid inhibitor (IC50=164.2 μM). By binding to the CA NTD-NTD hexamerization interface and the R173 region of CTD (Kd=66.3 μM), I-XW-053 disrupts capsid function and reduces polymerization levels. I-XW-053 effectively blocks HIV-1 uncoating, inhibits reverse transcription and early replication, and exhibits broad-spectrum activity against primary HIV-1 isolates in peripheral blood mononuclear cells. I-XW-053 can be widely used in studies related to HIV-1 infection .
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