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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
82 Results for "
PMS/INT
" in MedChemExpress (MCE) Product Catalog:
Products (82)
82 Results for "PMS/INT" in MCE Product Catalog:
88
88 Publications Verification
Synonyms: INT-747; 6-ECDCA; 6-Ethylchenodeoxycholic acid
Obeticholic acid (INT-747) is a potent, selective and orally active FXR agonist with an EC50 of 99 nM. Obeticholic acid has anticholeretic and anti-inflammation effect. Obeticholic acid also induces autophagy .
49
Research Areas:
INT-777 is a potent TGR5 agonist with an EC50 of 0.82 μM .
8
8 Cited Publications
Cat. No.: HY-D0937
CAS No.: 65162-13-2
Synonyms: 1-Methoxy PMS; 1-Methoxyphenazine methosulfate
6
6 Cited Publications
Research Areas:
INT-767 is a dual farnesoid X receptor (FXR)/TGR5 agonist with mean EC50s of 30 and 630 nM, respectively .
4
4 Cited Publications
Synonyms: Iodonitrotetrazolium chloride; p-Iodonitrotetrazolium Violet
3
3 Cited Publications
Synonyms: Cytidine triphosphate; 5'-CTP
1
1 Cited Publications
Cat. No.: HY-P700065AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGF3; Heparin-Binding Growth Factor 3; Prev. INT2; Proto-Oncogene INT-2; HBGF-3; Oncogene INT2; Fibroblast Growth Factor 3 (Murine Mammary Tumor Virus INTegration Site (V-INT-2) Oncogene Homolog); FGF-3; V-INT2 Murine Mammary Tumor Virus INTegration Site
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P70615
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1RL1; ST2V; INTerleukin 1 Receptor Like 1; Homolog Of Mouse Growth Stimulation-Expressed; DER4; Suppressor Of Tumorigenicity 2; ST2; INTerleukin 1 Receptor-Like 1 Isoform 2; T1; INTerleukin 1 Receptor-Like 1 Isoform 1; INTerleukin-1 Receptor-Like 1; INT
Species:
Human
Source:
HEK293
Cat. No.: HY-P99654
CAS No.: 2245205-37-0
Synonyms: INT-001
Target:
Research Areas:
Synonyms: PH94B
Target:
Research Areas:
Fasedienol (PH94B) is a neurochemical stimulator of the vomeronasal organ (VON). Fasedienol significantly increases Ca ++. Fasedienol modulates the olfactory amygdala circuitry of fear and anxiety to alleviate symptoms of PMS and anxiety .
Cat. No.: HY-173455
CAS No.: 2930070-08-7
Target:
Research Areas:
NP1867 is a potent, selective, covalent PMS2 inhibitor. NP1867 functionally inhibits DNA mismatch repair. NP1867 enhances immune surveillance. NP1867 can be used in the research of colorectal cancer .
Cat. No.: HY-P990059
CAS No.: 2760250-47-1
Synonyms: INT-016; AZD8205 Antibody
Target:
Research Areas:
Cat. No.: HY-P991699
CAS No.: 3035710-69-8
Synonyms: AZD9829 antibody; INT-020
Target:
Research Areas:
Synonyms: INT131
Target:
Research Areas:
AMG131 (INT131) is a potent non-thiazolidinedione (TZD) selective peroxisome proliferator-activated receptor γ modulator (SPPARM). AMG131 binds to PPARγ within the same binding pocket as the TZDs, but occupies a unique space in the pocket and contacts the receptor at distinct points from the TZDs. AMG131 is promising for research of type-2 diabetes mellitus .
HDAC3-IN-T247 is a potent and selective HDAC3 (histone deacetylase 3) inhibitor, with an IC50 of 0.24 µM. HDAC3-IN-T247 induces a selective increase of NF-κB acetylation in HCT116 cells. HDAC3-IN-T247 shows anticancer and antiviral activity. HDAC3-IN-T247 inhibits growth of cancer cells, and activates HIV gene expression in latent HIV-infected cells .
Cat. No.: HY-P991164
CAS No.: 2975630-15-8
Synonyms: AZD5335 Antibody; INT-019
Target:
Research Areas:
Cat. No.: HY-156994
CAS No.: 1426160-58-8
Research Areas:
ASGPR ligand-1 (Compound int-CC2) is an asialoglycoprotein receptor (ASGPR) ligand with a binding Kd value of 0.9 nM. ASGPR ligand-1 is applicable to research on lysosome degradation-related diseases .
Synonyms: S-EMCA R enantiomer
Research Areas:
INT-777 (R-enantiomer) is the R-enantiomer of INT-777, with EC50 of 4.79 μM for TGR5, and less potent than INT-777.
Category:
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
