419 Results for "

Plant Inducers

" in MedChemExpress (MCE) Product Catalog:
Products (419)

419 Results for "Plant Inducers" in MCE Product Catalog:

116
Palmitic acid
Palmitic acid
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116 Publications Verification
Cat. No.: HY-N0830
CAS No.: 57-10-3
Category:  

Cardiovascular Disease Natural Products Neurological Disease Plants Endogenous metabolite Biological Pesticide Research Agricultural Research Human Gut Microbiota Metabolites other families Microorganisms Animals Disease Research Fields Cancer

Target:  

Environmental Pollutants Endogenous Metabolite HSP

Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells. Palmitic acid is used to establish a cell steatosis model .
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116
Palmitic acid sodium
Palmitic acid sodium
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116 Publications Verification
Cat. No.: HY-N0830B
CAS No.: 408-35-5
Palmitic acid sodium is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid sodium can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells. Palmitic acid sodium is used to establish a cell steatosis model .
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85
Kaempferol
Kaempferol
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85 Cited Publications
Cat. No.: HY-14590
CAS No.: 520-18-3
Purity:  99.92%
Synonyms: Kempferol; Robigenin
Category:  

Flavonols Anti-aging Plants Endogenous metabolite Human Gut Microbiota Metabolites other families Flavonoids Microorganisms Sunscreen Phenols Polyphenols Cosmetic Research Disease Research Fields Cancer

Target:  

Estrogen Receptor/ERR Autophagy Mitophagy Apoptosis HIV Parasite Endogenous Metabolite

Kaempferol (Kempferol), a flavonoid found in many edible plants, inhibits estrogen receptor α expression in breast cancer cells and induces apoptosis in glioblastoma cells and lung cancer cells by activation of MEK-MAPK. Kaempferol can be uesd for the research of breast cancer .
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41
Paeoniflorin
Paeoniflorin
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41 Cited Publications
Cat. No.: HY-N0293
CAS No.: 23180-57-6
Synonyms: Peoniflorin
Category:  

Other Monoterpenes Paeonia lactiflora Pall. Terpenoids Plants Paeoniaceae

Target:  

HSP

Paeoniflorin is a heat shock protein-inducing compound and commonly exists in the plants of Paeoniaceae family, with various biological activities, including anticancer activity, anti-inflammatory activity, enhancing cognition and attenuating learning impairment, anti-oxidative stress, antiplatelet aggregation, expansion of blood vessels, and reducing blood viscosity .
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34
Rutin hydrate
Rutin hydrate
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34 Cited Publications
Cat. No.: HY-N0148A
CAS No.: 207671-50-9
Synonyms: Rutoside hydrate; Quercetin 3-O-rutinoside hydrate
Category:  

Flavonols other families Flavonoids Phenols Polyphenols Plants

Target:  

Amyloid-β Autophagy Apoptosis Endogenous Metabolite

Rutin (Rutoside) hydrate is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin hydrate can cross the blood brain barrier. Rutin hydrate attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress .
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34
Rutin
Rutin
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34 Cited Publications
Cat. No.: HY-N0148
CAS No.: 153-18-4
Synonyms: Rutoside; Quercetin 3-O-rutinoside
Category:  

Flavonols Plants other families Flavonoids Leguminosae Sunscreen Phenols Polyphenols Cosmetic Research Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer

Target:  

Amyloid-β Autophagy Apoptosis Endogenous Metabolite

Rutin (Rutoside) is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin is also a CBR1 inhibitor, which can cross the blood brain barrier. Rutin attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress .
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26
Linoleic acid
Linoleic acid
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26 Cited Publications
Cat. No.: HY-N0729
CAS No.: 60-33-3
Category:  

Cardiovascular Disease Ketones, Aldehydes, Acids Disease markers Endocrine diseases Endogenous metabolite Disease Research Fields Biological Pesticide Research Agricultural Research

Target:  

Environmental Pollutants Endogenous Metabolite

Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .
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23
Narciclasine
Narciclasine
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23 Cited Publications
Cat. No.: HY-16563
CAS No.: 29477-83-6
Synonyms: Lycoricidinol
Category:  

Alkaloids Narcissus tazetta Linn. var. chinensis M.Roemer Plants Disease Research Fields Isoquinoline Alkaloids Amaryllidaceae Cancer Agricultural Research

Target:  

ROCK

Narciclasine is a plant growth modulator. Narciclasine modulates the Rho/Rho kinase/LIM kinase/cofilin signaling pathway, greatly increasing GTPase RhoA activity as well as inducing actin stress fiber formation in a RhoA-dependent manner.
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22
Guggulsterone
Guggulsterone
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22 Cited Publications
Cat. No.: HY-107738
CAS No.: 95975-55-6
Purity:  99.81%
Synonyms: Z/E-Guggulsterone
Category:  

Triterpenes Terpenoids Plants Burseraceae Disease Research Fields Commiphora wightii Cancer

Target:  

Apoptosis JNK Akt Caspase FXR Autophagy

Guggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii. Guggulsterone inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products (IAP1, xIAP, Bfl-1/A1, Bcl-2, cFLIP and survivin), modulation of cell cycle proteins (cyclin D1 and c-Myc), activation of caspases and JNK, inhibition of Akt . Guggulsterone, a farnesoid X receptor (FXR) antagonist, with IC50s of 24.06 μM and 39.05 μM for (-)-(E)-Guggulsterone (HY-N7781) and (Z)-Guggulsterone (HY-110066), respectively .
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16
Epibrassinolide
Epibrassinolide
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16 Cited Publications
Cat. No.: HY-N0848
CAS No.: 78821-43-9
Synonyms: 24-Epibrassinolide; B1105; BP55
Category:  

Natural Products Plants Biological Pesticide Research Agricultural Research Brassinolide Phytohormone Brassicaceae Brassica campestris L. Disease Research Fields Cancer

Target:  

Environmental Pollutants Apoptosis Plant Growth Regulators

Epibrassinolide (24-Epibrassinolide) is a ubiquitously occurring plant growth hormone which shows great potential to alleviate heavy metals and pesticide stress in plants . Epibrassinolide is a potential apoptotic inducer in various cancer cells without affecting the non-tumor cell growth .
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15
D-Mannitol
D-Mannitol
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15 Cited Publications
Cat. No.: HY-N0378
CAS No.: 69-65-8
Synonyms: Mannitol; Mannite
Category:  

Natural Products other families Metabolic Disease Plants Endogenous metabolite Disease Research Fields Sweeteners Food Research

Target:  

Environmental Pollutants Endogenous Metabolite Apoptosis PGC-1α PKA Adrenergic Receptor

D-Mannitol (Mannitol) is an oral, resistant sugar widely used in the food and pharmaceutical industries to promote the absorption and retention of calcium and magnesium through cecal fermentation, while acting as a osmotic diuretic to reduce tissue edema. D-Mannitol can enhance brown fat formation, improve insulin effect, reduce blood sugar levels, And through the start the β3-adrenergic receptor (β3-AR), PGC1α and PKA induced by means of white fat cells into brown fat cells . D-Mannitol is commonly used to maintain osmotic pressure between the plant cytoplasm and the culture medium and protect cells when the cell wall is weakened or even removed .
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11
Dioscin
Dioscin
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11 Cited Publications
Cat. No.: HY-N0124
CAS No.: 19057-60-4
Synonyms: Collettiside III; CCRIS 4123
Category:  

other families Plants Disease Research Fields Cancer Steroids

Target:  

Autophagy Apoptosis

Dioscin (CCRIS 4123; Collettiside III) is a natural plant-derived steroidal saponin that has good anti-cancer activity against a variety of cancer cells. Dioscin causes DNA damage and induces apoptosis in HeLa and SiHa cells. Dioscin regulates ROS-mediated DNA damage and mitochondrial signaling pathways, exerting anticancer activity .
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11
Ginsenoside Rk1
Ginsenoside Rk1
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11 Cited Publications
Cat. No.: HY-N2515
CAS No.: 494753-69-4
Category:  

Panax ginseng C. A. Meyer Triterpenes Terpenoids Plants Disease Research Fields Inflammation/Immunology Araliaceae

Target:  

NF-κB PI3K JAK Apoptosis

Ginsenoside Rk1 is a unique component created by processing the ginseng plant (mainly Sung Ginseng, SG) at high temperatures . Ginsenoside Rk1 has anti-inflammatory effect, suppresses the activation of Jak2/Stat3 signaling pathway and NF-κB . Ginsenoside Rk1 has anti-tumor effect, antiplatelet aggregation activities, anti-insulin resistance, nephroprotective effect, antimicrobial effect, cognitive function enhancement, lipid accumulation reduction and prevents osteoporosis . Ginsenoside Rk1 induces cell apoptosis by triggering intracellular reactive oxygen species (ROS) generation and blocking PI3K/Akt pathway .
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10
Morin
Morin
0 Images
10 Cited Publications
Cat. No.: HY-N0621
CAS No.: 480-16-0
Category:  

Flavonols other families Flavonoids Phenols Polyphenols Plants Disease Research Fields Cancer

Target:  

Environmental Pollutants Reactive Oxygen Species (ROS) Phosphatase Insulin Receptor Apoptosis

Morin is an orally active plant-derived flavonoid. Morin inhibits ROS generation. Morin induces Apoptosis. Morin inhibits PTP1B (IC50 of 15 μM) and activates the insulin receptor. Morin has a detoxifying effect. Morin can be used in diabetes, leukemia, colon cancer, cervical cancer, Parkinson's disease and hypertension research .
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10
Carvacrol
Carvacrol
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10 Cited Publications
Cat. No.: HY-N0711
CAS No.: 499-75-2
Synonyms: Cymophenol
Category:  

Preservatives Monophenols Labiatae Phenols Plants Derris elliptica (Roxb.) Benth. Disease Research Fields Inflammation/Immunology Food Research

Target:  

Environmental Pollutants Apoptosis Endogenous Metabolite Notch Fungal Bacterial

Carvacrol is an orally active and blood-brain barrier-permeable monoterpenic phenol that can be extract from an abundant number of aromatic plants, including thyme and oregano, possessing antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, hepatoprotective, spasmolytic, and vasorelaxant properties. Carvacrol also causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis. Carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations .
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10
Spermine tetrahydrochloride
Spermine tetrahydrochloride
0 Images
10 Cited Publications
Cat. No.: HY-B1777A
CAS No.: 306-67-2
Category:  

Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Bacterial Reactive Oxygen Species (ROS) DNA/RNA Synthesis

Spermine tetrahydrochloride is a polyamine nitric oxide donor that can provide nitric oxide to platelets and inhibit platelet activation to a certain extent concentration-dependently. Spermine tetrahydrochloride occurs in mammalian tissues, plants, bacteria, ribosomes and bacteriophage. Spermine tetrahydrochloride inhibits primary human embryo lung fibroblasts in vitro. Spermine is a natural antioxidant and anti-inflammatory agent. Spermine is known to inhibit some bacterial cultures, especially strains of Staphylococcus aureus. Spermine induces neurotoxicity in the striarum dose-dependently. Spermine can reversibly inhibits DNA synthetic response, mixed lymphocyte response and the induction of cytolytic lymphocyte response in primary cultures of murine spleen cells .
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8
β-Elemene
β-Elemene
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8 Cited Publications
Cat. No.: HY-107324
CAS No.: 515-13-9
Purity:  99.62%
Synonyms: (-)-β-Elemene; Levo-β-elemene
Category:  

Terpenoids Sesquiterpenes Curcuma aromatica Salisb. cv. Wenyujin Plants Disease Research Fields Cancer Zingiberaceae

Target:  

Apoptosis

β-Elemene ((-)-β-Elemene; Levo-β-elemene) is isolated from natural plant Curcuma aromatica with an antitumor activity. β-Elemene can induce cell apoptosis.
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8
Aloperine
Aloperine
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8 Cited Publications
Cat. No.: HY-13516
CAS No.: 56293-29-9
Purity:  ≥98.0%
Category:  

Infection Alkaloids Piperidine Alkaloids Leguminosae Sophora alopecuroides L Plants Disease Research Fields Inflammation/Immunology

Target:  

Apoptosis Autophagy Filovirus HIV

Aloperine is an alkaloid in sophora plants such as Sophora alopecuroides L, which has shown anti-cancer, anti-inflammatory and anti-virus properties . Aloperine is widely used to treat patients with allergic contact dermatitis eczema and other skin inflammation in China . Aloperine induces apoptosis and autophagy in HL-60 cells .
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8
Daphnetin
Daphnetin
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8 Cited Publications
Cat. No.: HY-N0281
CAS No.: 486-35-1
Synonyms: 7,8-Dihydroxycoumarin
Category:  

Daphne  Thymelaeaceae Coumarins Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields Cancer

Target:  

EGFR PKA PKC Autophagy Apoptosis AMPK Akt mTOR Reactive Oxygen Species (ROS) Caspase Bcl-2 Family PARP Parasite

Daphnetin (7,8-dihydroxycoumarin), one coumarin derivative can be found in plants of the Genus Daphne, is a potent, oral active protein kinase inhibitor, with IC50s of 7.67 μM, 9.33 μM and 25.01 μM for EGFR, PKA and PKC in vitro, respectively. Daphnetin triggers ROS-induced cell apoptosis and induces cytoprotective autophagy by modulating the AMPK/Akt/mTOR pathway. Daphnetin has anti-inflammation activitity and inhibits TNF-α, IL-1β, ROS, and MDA production. Daphnetin has schizontocidal activity against malaria parasites. Daphnetin can be used for rheumatoid arthritis , cancer and anti-malarian research .
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7
Hinokiflavone
Hinokiflavone
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7 Cited Publications
Cat. No.: HY-N2360
CAS No.: 19202-36-9
Category:  

Flavonoids Phenols Polyphenols Selaginellaceae Plants Disease Research Fields Selaginella tamariscina (P. Beauv.) Spring Biflavones Cancer

Target:  

E1/E2/E3 Enzyme Apoptosis MMP ClpP

Hinokiflavone is a novel modulator of pre-mRNA splicing activity extracted from plants with anti-inflammatory, anti-tumor and antiviral activities. Hinokiflavone is also a potent inhibitor for matrix metalloproteinases (MMPs). Hinokiflavone attenuates the virulence of Methicillin (HY-121544)-resistant staphylococcus aureus by inhibiting caseinolytic protease P (ClpP) with an IC50 value of 34.36 mg/mL. Hinokiflavone induces apoptosis via the reactive oxygen species-mitochondria-mediated apoptotic pathway and inhibits tumor cell migration and invasion. Hinokiflavone is a SUMO protease inhibitor against sentrin-specific protease 1 (SENP1) activity .
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