103 Results for "

SAP

" in MedChemExpress (MCE) Product Catalog:
Products (103)

103 Results for "SAP" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-A0059
CAS No.: 4936-47-4
Synonyms: NF 113; SAP 113; Methylmercadone
Nifuratel (NF 113) is an orally active broad-spectrum antibiotic with antiprotozoal, antibacterial, anticancer and anti-inflammatory activities, and has good inhibitory effects on Candida and Trichomonas. Nifuratel is also a STAT3 inhibitor, which significantly inhibits the growth and proliferation of human gastric cancer cells and induces apoptosis. In addition, Nifuratel also inhibits mast cell-mediated antigen hypersensitivity reactions and can be used in the study of IgE-mediated allergic diseases .
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2
2 Cited Publications
Cat. No.: HY-P71067
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Serum Amyloid P-Component; SAP; 9.5S Alpha-1-Glycoprotein; APCS; PTX2
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-129434A
CAS No.: 21651-62-7
Purity:  99.69%
4aα,7α,7aα-Nepetalactone is an iridoid compound, a TRPA1 agonist, a repellent, and an attractant. 4aα,7α,7aα-Nepetalactone can be isolated from the oil of N. crispa. 4aα,7α,7aα-Nepetalactone induces repellent responses in three sap-sucking pests (Chinese psyllid, Asian citrus psyllid, and western flower thrips) via PKCα. Nepetalactone attracts two predatory lady beetles (Harmonia axyridis and Propylea japonica) through CaMKII. 4aα,7α,7aα-Nepetalactone causes mortality in Pogonomyrmex sp. ants. 4aα,7α,7aα-Nepetalactone can be used in studies related to bacterial infections and mandibulate pest infestations .
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1
1 Cited Publications
Cat. No.: HY-P76553
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Proactivator polypeptide; SAPosin-A; PSAP; GLBA; SAP1
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P77159
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Proactivator polypeptide; SAPosin-A; PSAP; GLBA; SAP1
Species:  
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Cat. No.: HY-N7354
CAS No.: 86-68-0
Quininic acid, purified from Eucalyptus globulus, cinchona bark, and other plant products, is the most abundant organic acid .
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Cat. No.: HY-N0313
CAS No.: 514-47-6
Euphol is a tetracyclic triterpene alcohol isolated from the sap of Euphorbia tirucalli with anti-mutagenic, anti-inflammatory and immunomodulatory effects, orally active. Euphol inhibits the monoacylglycerol lipase (MGL) activity via a reversible mechanism (IC50=315 nM). MGL inhibition in the periphery modulates the endocannabinoid system to block the development of inflammatory pain .
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Cat. No.: HY-P99358
CAS No.: 1662664-56-3
Synonyms: GSK 2398852; Anti-Serum Amyloid P/SAP Reference Antibody (dezamizumab)

Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Dezamizumab (GSK 2398852) is a fully humanized clonal IgG1 antibody against serum amyloid P component (SAP) with complement activation and amyloid clearance-inducing activities. Dezamizumab binds to SAP associated with amyloid deposits to form complexes that activate complement and mediate phagocytic clearance, triggering activation of the classical complement pathway. Dezamizumab can be used for the research of systemic amyloidosis .
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Cat. No.: HY-101861
CAS No.: 224624-80-0
Purity:  99.19%
Synonyms: CPHPC; Ro63-8695; GSK2315698
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Miridesap is a ligand for serum amyloid P component (SAP) and intends to inhibit and dissociate SAP binding to amyloid fibrils and tangles.
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Cat. No.: HY-19828
CAS No.: 142861-00-5
Synonyms: GEX1A
Herboxidiene (GEX1A) is a potent phytotoxic polyketide from Streptomyces sp. A7847 with a diverse range of activities, including herbicidal, anti-cholesterol, anti-tumor effects. Herboxidiene inhibits the pre-mRNA splicing process by binding to spliceosome-associated protein (SAP) 155, a subunit of SF3b, in the splicesome .
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Cat. No.: HY-P2315
CAS No.: 452274-53-2
Synonyms: HβD-1
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Human β-defensin-1 (HβD-1) is a cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by all epithelial surfaces, but also by circulatory cells and cells of the reproductive tract. Human β-defensin-1 has antimicrobial activities against a broad-sperm bacteria .
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Cat. No.: HY-114117
CAS No.: 1477919-27-9
Purity:  98.21%
Synonyms: GF-3242
Research Areas:  

Infection

Tyclopyrazoflor (GF-3242) is a pyridylpyrazole Insecticide. Tyclopyrazoflor exhibits excellent insecticidal efficacy against sap-sucking insects. Tyclopyrazoflor effectively controls insect pests caused by Myzus persicae and Bemisia tabaci larvae .\n

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Cat. No.: HY-W072025
CAS No.: 38205-55-9
CYP2E1-IN-1 (Compound 10) is an orally active cytochrome P450 2E1 (CYP2E1) inhibitor with a Kd of 7.02 μM, an IC50 of 1.64 μM, and a Ki of 0.897 μM. CYP2E1-IN-1 activates the Nrf2/HO-1 signaling pathway and inhibits ROS production, thereby alleviating pancreatic injury. CYP2E1-IN-1 has significant anti-inflammatory and antioxidant activities and can effectively reduce inflammation and oxidative stress in severe acute pancreatitis (SAP). CYP2E1-IN-1 can be used in the study of SAP and other inflammatory-related diseases .
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Cat. No.: HY-P10709A
Research Areas:  

Cardiovascular Disease Cancer

CREKA peptide acetate is a short peptide sequence, belonging to self-assembling peptides (SAPs), which can self-assemble into functional nanostructures, typically nanofibers, under physiological conditions. CREKA peptide acetate can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity .
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Cat. No.: HY-P3361A
IDR-1018 acetate is an innate defense regulator conjugate, with MICs of 16 μg/mL for MRSA USA300 LAC, MRSA SAP 0017 and S. epidermidis ATCC14990. IDR-1018 acetate can be used to synthesis V-IDR1018 (vancomycin-innate defense regulator conjugate) .
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Cat. No.: HY-115684
CAS No.: 1653-30-1
Purity:  ≥98.0%
Synonyms: Undecan-2-ol
2-Undecanol (Undecan-2-ol) is a male specific volatile identified from the sap beetle Lobiopa insularis. 2-undecanol is a flower emitted volatile, used by various species of Hymenoptera as a pheromone component .
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Cat. No.: HY-P3361
CAS No.: 1453221-07-2
IDR-1018 is an innate defense regulator conjugate, with MICs of 16 μg/mL for MRSA USA300 LAC, MRSA SAP 0017 and S. epidermidis ATCC14990. IDR-1018 can be used to synthesis V-IDR1018 (vancomycin-innate defense regulator conjugate) .
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Cat. No.: HY-118044
CAS No.: 133538-58-6
Research Areas:  

Cardiovascular Disease

I-SAP is a radioiodinated TXA2/PGH2 receptor antagonist. The bind between I-SAP and the receptors, is inhibited by the histidine modifying reagent diethyl-pyrocarbonate (DEPC) .
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Cat. No.: HY-P10462
CAS No.: 1403753-45-6
Synonyms: Synthetic anti-inflammatory peptide 15
Target:  

HDAC NF-κB

Research Areas:  

Inflammation/Immunology

SAP15 (Synthetic anti-inflammatory peptide 15) is a synthetic anti-inflammatory peptide consisting of 15 amino acids designed from human beta-defensin 3. SAP15 has the ability to penetrate cells and is able to induce downregulation of intracellular inflammation. SAP15 inhibits inflammation by inhibiting the phosphorylation of HDAC5 and thereby reducing the phosphorylation of NF-κB p65. SAP15 inhibits HDAC5 and NF-κB p65 phosphorylation in LPS (HY-D1056)-induced macrophages. SAP15 increases the expression of aggrecan and type II collagen and decreases the expression of osteocalcin in LPS-induced chondrocytes. SAP15 can be used in the study of inflammation regulation and anti-inflammatory therapy of biomaterials .
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Cat. No.: HY-P4054
CAS No.: 1426415-02-2
Target:  

Peptides

Research Areas:  

Others

IEIK 13 is a self-assembling peptide (SAP) sequence. IEIK 13 can be used for the research of cartilage tissue engineering
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