20 Results for "

SGC7901

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "SGC7901" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-W015084
CAS No.: 14901-07-6
β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. Anti-cancer activity .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-155360
CAS No.: 3008262-76-5
Purity:  99.05%
Target:  

YAP Apoptosis

Research Areas:  

Cancer

MY-1076 is an inhibitor of YAP. MY-1076 induces YAP degradation and cell apoptosis. MY-1076 inhibits MGC-803, SGC-7901, HCT-116 and KYSE450 cells proliferation with IC50 s of 0.019, 0.017, 0.020 and 0.044 μM, respectively .
loading...
    loading...
Cat. No.: HY-N7980
CAS No.: 2170211-22-8
Rubipodanone A, a naphthohydroquinone dimer, shows cytotoxicity against A549, BEL-7402, HeLa, HepG2, SGC-7901 and U251 cells. Rubipodanone A also shows obvious activating effect at 20 and 40 μM for NF-κB .
loading...
    loading...
Cat. No.: HY-N10201
CAS No.: 1221163-94-5
Cytoglobosin C, a cytochalasan derivative, shows potent cytotoxicity against both SGC-7901 and A549 cell lines (IC50<10 μM) .
loading...
    loading...
Cat. No.: HY-124398
CAS No.: 591242-70-5
Target:  

PAK

Research Areas:  

Cancer

GL-1196 is an inhibitor of PAK4. GL-1196 can suppress the proliferation and invasion of gastric cancer cells. GL-1196 inhibits PAK4-mediated signaling pathways. GL-1196 can hinder the proliferation of human gastric cancer cells through suppressing PAK4/c-Src/EGFR/CyclinD1 and CDK4/6. GL-1196 can reduce filamentous pseudopodia formation and induce filamentous pseudopodia formation and promote cell elongation in SGC7901 and BGC823 cells. GL-1196 can be studied in anti-cancer research .
loading...
    loading...
Cat. No.: HY-N1841
CAS No.: 189322-67-6
Synonyms: 3'-Hydroxyrocaglamide
Rocaglamide D (3'-Hydroxyrocaglamide) (compound 1) is a lignan that can be found in Aglaia odorata. Rocaglamide D shows cytotoxicity with IC50s of 0.32, 0.12, 0.25 µM for HeLa, SGC-7901, A549 cells, respectively .
loading...
    loading...
Cat. No.: HY-161351
Target:  

Akt STAT Apoptosis

Research Areas:  

Cancer

STAT3/AKT-IN-1 is a dual inhibitor for the signal transducer and activator of transcription 3 (STAT3) and protein kinase B (AKT) signalling pathway, exhibits antitumor activity against gastric cancer and induces cell apoptosis in SGC-7901 cells .
loading...
    loading...
Cat. No.: HY-W015084S
β-Ionone- 13C3 is the 13C-labeled β-Ionone. β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. Anti-cancer activity .
loading...
    loading...
Cat. No.: HY-156098
CAS No.: 3098360-50-7
Target:  

c-Met/HGFR

Research Areas:  

Cancer

c-Met-IN-19 (Compound 21j) is a c-Met inhibitor (IC50: 1.99 nM). c-Met-IN-19 shows cytotoxicity against A549, HT-29, SGC-7901, MDA-MB-231 cells with IC50s of 0.25, 0.36, 0.98, 0.76 μM .
loading...
    loading...
Cat. No.: HY-W015084R
CAS No.: 14901-07-6
β-Ionone (Standard) is the analytical standard of β-Ionone. This product is intended for research and analytical applications. β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. Anti-cancer activity .
loading...
    loading...
Cat. No.: HY-146311
CAS No.: 2296731-38-7
Target:  

Microtubule/Tubulin

Research Areas:  

Cancer

Tubulin polymerization-IN-16 (compound 5g) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-16 shows most potent against cancer cells, with IC50 values of 0.084-0.221 μM. Tubulin polymerization-IN-16 potently disrupts microtubule/tubulin dynamics, induces cell cycle arrest at G2/M phase in SGC-7901 cells .
loading...
    loading...
Cat. No.: HY-176162
Research Areas:  

Cancer

BJ-13 is a reactive oxygen species (ROS) inducer that can lead to mitochondrial membrane potential collapse and caspase-dependent apoptosis. BJ-13 inhibits the proliferation of SGC-7901, U-87MG, and HepG-2 cancer cells (IC50 values of 15.33, 27.18, and 20.44 nM, respectively). BJ-13 can be used in the study of gastric cancer .
loading...
    loading...
Cat. No.: HY-N13136
CAS No.: 220095-97-6
Timosaponin D, a natural steroid saponin, can be obtained from the rhizome of Anemarrhena asphodeloides. The IC50 values ​​of Timosaponin D against HepG2 and SGC7901 cells are 43.90 and 57.90 μM, respectively. Timosaponin D can be used in anticancer research .
loading...
    loading...
Cat. No.: HY-147947
CAS No.: 2521560-46-1
Target:  

Microtubule/Tubulin

Research Areas:  

Cancer

Tubulin polymerization-IN-30 (compound 6e) is a potent Tubulin polymerization inhibitor. Tubulin polymerization-IN-30 is a colchicine binding site inhibitor. Tubulin polymerization-IN-30 can disrupt intracellular microtubule organization, arrest cell cycle at the G2/M phase. Tubulin polymerization-IN-30 exhibits the high potency against the cancer cell lines including SGC-7901, A549 and HeLa, with IC50 values of 2.16, 2.21, and 0.403 μM .
loading...
    loading...
Cat. No.: HY-W015084AR
CAS No.: 79-77-6
Synonyms: β-Lonone (Standard)
(E)-β-Ionone (Standard) is the analytical standard of (E)-β-Ionone. This product is intended for research and analytical applications. (E)-β-Ionone is the isomer of β-Ionone (HY-W015084). β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. β-Ionone has anti-cancer activity .
loading...
    loading...
Cat. No.: HY-168102
Research Areas:  

Cancer

Antiproliferative agent-59 (Compound 14u) is an inhibitor for tubulin polymerization. Antiproliferative agent-59 exhibits antiproliferative activities against cancer cells Huh7, SGC-7901, and MCF-7 with IC50 of 0.03, 0.18, and 0.13μM. Antiproliferative agent-59 arrests the cell cycle at G2/M phase and induces apoptosis in Huh7 cell. Antiproliferative agent-59 exhibits antitumor efficacy against liver cancer in Huh7 xenograft mouse models, without significant toxicity .
loading...
    loading...
Cat. No.: HY-N21592
CAS No.: 1628026-28-7
12α-Hydroxymeliatoosenin I is a limonoid compound found in the roots of Trichilia sinensis. In the MTT assay, 12α-Hydroxymeliatoosenin I exhibits no significant growth inhibitory activity against K562, SGC-7901, and BEL-7402 cells, with all IC50 values exceeding 40 μM. 12α-Hydroxymeliatoosenin I is applicable to studies related to limonoid natural products and tumor cell growth .
loading...
    loading...
Cat. No.: HY-N21698
CAS No.: 1253206-38-0
Uralodin B is a naturally occurring polycyclic polyprenylated acylphloroglucinol (PPAP) and is the C (30)-epimer of Uralodin C. It is found in the aerial parts of Hypericum henryi subsp. uraloides. Uralodin B exhibits cytotoxic activity against SGC7901 and HL-60 tumor cells. It is useful for research related to PPAP natural products and tumor cytotoxicity .
loading...
    loading...
Cat. No.: HY-N17005
CAS No.: 1448534-93-7
3-O-(p-Hydroxybenzoyl)serratriol is a serratene-type triterpenoid compound with low cytotoxicity against cancer cells (IC50 >100 μg/mL against three human cancer cell lines: K562, SMMC-7721, and SGC7901). 3-O-(p-Hydroxybenzoyl)serratriol can be naturally extracted from the whole plant of Palhinhaea cernua .
loading...
    loading...
Cat. No.: HY-N17349
CAS No.: 1646619-90-0
(23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol (compound 3) is a cytotoxin that can be found in the marine bryozoan Bugula neritina. (23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol shows weak cytotoxicity against SGC7901 cell with an IC50 value of 111.8 μM. (23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol can be used for the research of hepatocellular carcinoma, gastric carcinoma .
loading...
    loading...
  • 1