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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
SUMO2
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "SUMO2" in MCE Product Catalog:
39
39 Publications Verification
Target:
Domaines de recherche:
ML-792 is a potent and selective inhibitor of SAE/SUMO1 and SAE/SUMO2 in enzymatic assays (IC50 values of 3 and 11 nM, respectively) compared with NAE/NEDD8 and UAE/ubiquitin (IC50> values of 32 μM and >100 μM, respectively) .
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Target:
Domaines de recherche:
HB007 is a SUMO1 molecular glue degrader targeting CAPRIN1 and FBXO42. HB007 selectively binds CAPRIN1 to induce CAPRIN1-FBXO42 interaction, recruits SUMO1 to the CAPRIN1-CUL1-FBXO42 E3 ligase complex, and drives SUMO1 ubiquitination and degradation without affecting SUMO2/3. HB007 induces TCF4 deSUMOylation and proteasomal degradation to inhibit StarD7 transcriptional activity, reduces StarD7 mRNA and protein levels, and triggers ER stress and ROS production. HB007 can be used for the research of brain cancer, breast cancer, colon cancer, lung cancer [2] .
Cat. No.: HY-RS18410
Target:
Domaines de recherche:
Sumo2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sumo2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14026
Target:
Domaines de recherche:
SUMO2 Human Pre-designed siRNA Set A contains three designed siRNAs for SUMO2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24891
Target:
Domaines de recherche:
Sumo2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sumo2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P70974
Pureté: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SUMO2; SMT3 (Suppressor Of Mif Two 3, Yeast) Homolog 2; Prev. SMT3H2; SMT3 Suppressor Of Mif Two 3 Homolog 2; SMT3B; Sentrin 2; Small Ubiquitin-Related Modifier 2; Sentrin-2; Ubiquitin-Like Protein SMT3B; SUMO-3; SMT3 Homolog 2; SUMO-2; HSMT3; Smt3B; SMT3
Species:
Human
Source:
E. coli
Cat. No.: HY-108702R
CAS No.: 1644342-14-2
Target:
Domaines de recherche:
ML-792 (Standard) is the analytical standard of ML-792 (HY-108702). This product is intended for research and analytical applications. ML-792 is a potent and selective inhibitor of SAE/SUMO1 and SAE/SUMO2 in enzymatic assays (IC50 values of 3 and 11 nM, respectively) compared with NAE/NEDD8 and UAE/ubiquitin (IC50> values of 32 μM and >100 μM, respectively) .
Cat. No.: HY-P71346
Pureté: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SUMO3; SMT3 Suppressor Of Mif Two 3 Homolog 1; Prev. SMT3H1; Small Ubiquitin-Related Modifier 2; SMT3A; Ubiquitin-Like Protein SMT3B; Small Ubiquitin-Related Modifier 3; Ubiquitin-Like Protein SMT3A; SUMO-3; SMT3 Homolog 1; SMT3 Suppressor Of Mif Two 3 Ho
Species:
Human
Source:
HEK293
Cat. No.: HY-P87316
Synonyms: HSMT3 antibody; MGC117191 antibody; OTTHUMP00000115275 antibody; OTTHUMP00000115276 antibody; OTTHUMP00000115277 antibody; Sentrin 2 antibody; Small ubiquitin like modifier 2 antibody; Small ubiquitin related modifier 2 antibody; small ubiquitin-like modifier 3 antibody; small ubiquitin-related modifier 3 antibody
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
