Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
50 Results for "
Subtilisin
" in MedChemExpress (MCE) Product Catalog:
Products (50)
50 Results for "Subtilisin" in MCE Product Catalog:
Subtilisin (EC 3.4.21.14) is a bacterial serine protease. Subtilisin induces Apoptosis. Subtilisin stimulates the expression of pro-allergic cytokines (IL-1α, IL-33). Subtilisin induces prototypic allergic lung inflammation. Subtilisin exhibits anticancer activity against breast and colon cancer. Subtilisin shows antifouling activity. Subtilisin can be used as a detergent additive .
7
7 Publications Verification
Target:
研究分野:
PF-06446846 hydrochloride is an orally active and highly selective inhibitor of translation of Proprotein convertase subtilisin/kexin type 9 (PCSK9). PF-06446846 hydrochloride inhibits PCSK9 by inducing the ribosome to stall around codon 34 .
7
7 Publications Verification
製品番号: HY-120088
CAS 番号: 1632250-49-7
Target:
研究分野:
PF-06446846 is an orally active proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. PF-06446846 directly and selectively inhibits translation of PCSK9 by stalling the 80S ribosome in the proximity of codon region .
5
5 Cited Publications
Target:
研究分野:
SBC-115076 is a potent proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. PCSK9 is a proprotein convertase, which plays a crucial role in LDL receptor metabolism .
2
2 Cited Publications
製品番号: HY-P78747
純度: ≥ 90%, as determined by reducing SDS-PAGE.
別名: FURIN; Subtilisin-Like Proprotein Convertase 1; Prev. PCSK3; Paired Basic Amino Acid Cleaving Enzyme (Furin, Membrane Associated Receptor Protein); Prev. PACE; Furin (Paired Basic Amino Acid Cleaving Enzyme); Prev. FUR; Proprotein Convertase Subtilisin/Ke
Species:
Human
Source:
HEK293
1
1 Cited Publications
Target:
SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor extracted from patent WO2014150395A1 .
1
1 Cited Publications
製品番号: HY-P70545A
純度: ≥ 95%, as determined by reducing SDS-PAGE.
別名: PCSK9; PC9; Prev. HCHOLA3; Hypercholesterolemia, Autosomal Dominant 3; NARC-1; Neural Apoptosis Regulated Convertase 1; Subtilisin/Kexin-Like Protease PC9; Neural Apoptosis-Regulated Convertase 1; FH3; LDLCQ1; Proprotein Convertase 9; FHCL3; NARC1; Proprotein Convertase Subtilisin/Kexin Type 9; Convertase Subtilisin/Kexin Type 9 Preproprotein
Species:
Human
Source:
HEK293
1
1 Cited Publications
製品番号: HY-P73340
純度: ≥ 95%, as determined by reducing SDS-PAGE.
別名: PCSK9; PC9; Prev. HCHOLA3; Hypercholesterolemia, Autosomal Dominant 3; NARC-1; Neural Apoptosis Regulated Convertase 1; Subtilisin/Kexin-Like Protease PC9; Neural Apoptosis-Regulated Convertase 1; FH3; LDLCQ1; Proprotein Convertase 9; FHCL3; NARC1; Propro
Species:
Rat
Source:
HEK293
1
1 Cited Publications
製品番号: HY-P73728
純度: ≥ 90%, as determined by reducing SDS-PAGE.
別名: PCSK9; PC9; Prev. HCHOLA3; Hypercholesterolemia, Autosomal Dominant 3; NARC-1; Neural Apoptosis Regulated Convertase 1; Subtilisin/Kexin-Like Protease PC9; Neural Apoptosis-Regulated Convertase 1; FH3; LDLCQ1; Proprotein Convertase 9; FHCL3; NARC1; Propro
Species:
Human
Source:
HEK293
1
1 Cited Publications
製品番号: HY-P71189A
純度: ≥ 95%, as determined by reducing SDS-PAGE.
別名: PCSK9; PC9; Prev. HCHOLA3; Hypercholesterolemia, Autosomal Dominant 3; NARC-1; Neural Apoptosis Regulated Convertase 1; Subtilisin/Kexin-Like Protease PC9; Neural Apoptosis-Regulated Convertase 1; FH3; LDLCQ1; Proprotein Convertase 9; FHCL3; NARC1; Propro
Species:
Mouse
Source:
HEK293
Target:
研究分野:
Subtilisin, bacillus licheniformis (Bacillopeptidaseb) is a serine endopeptidase that cleaves peptide bonds with broad substrate specificity. Subtilisin, bacillus licheniformis exhibits P1 site preference (the first residue at the N-terminus of the cleavage site). Subtilisin, bacillus licheniformis can be used in protein hydrolysis, detergents, proteomics, and other fields .
製品番号: HY-148687A
純度: 93.97%
Target:
研究分野:
SPC5001 sodium is a locked nucleic acid (LNA)-modifed antisense oligonucleotide (ASO) complementary to human PCSK9 (proprotein convertase subtilisin/kexin type 9) mRNA. SPC5001 sodium can be used for the research of hypercholesterolemia. SPC5001 sodium sequence: 5′-TGmCTACAAAACmCmCA-3′ .
製品番号: HY-158827A
Target:
研究分野:
AZD8233 sodium, a liver-targeting antisense oligonucleotide (ASO), inhibits subtilisin/kexin type 9 (PCSK9) protein synthesis. AZD8233 sodium increases the available LDL receptors by reducing PCSK9 levels, thereby clearing LDL from the blood and decreasing LDL-C levels.
製品番号: HY-P4517
CAS 番号: 108318-36-1
製品番号: HY-P4516
CAS 番号: 104634-10-8
Target:
PF-06815345 hydrochloride is an orally active and potent inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9) with an IC50 value of 13.4 μM. PF-06815345 hydrochloride significantly decreases the PCSK9 level in vivo in mouse .
製品番号: HY-P4582
CAS 番号: 110906-89-3
別名: Suc-FAAF-pNA
Target:
研究分野:
製品番号: HY-P5062A
別名: Decanoyl-Arg-Val-Arg-Lys-chloromethylketone TFA
製品番号: HY-P3947
CAS 番号: 147471-56-5
Target:
研究分野:
製品番号: HY-148687
Target:
研究分野:
SPC5001 is a locked nucleic acid (LNA)-modifed antisense oligonucleotide (ASO) complementary to human PCSK9 (proprotein convertase subtilisin/kexin type 9) mRNA. SPC5001 can be used for the research of hypercholesterolemia. SPC5001 sequence: 5′-TGmCTACAAAACmCmCA-3′ .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
