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alpha-adrenergic receptor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (6) Adrenergic Receptor (57) Amyloid-β (3) AP-1 (1) Apoptosis (1) Autophagy (3) Bacterial (1) Calcium Channel (1) Chloride Channel (1) Cholinesterase (ChE) (1) Dopamine Receptor (9) Drug Derivative (1) Endogenous Metabolite (5) Environmental Pollutants (1) GABA Receptor (1) Histamine Receptor (4) Interleukin Related (5) Isotope-Labeled Compounds (6) mAChR (1) Monoamine Oxidase (4) NF-κB (1) Parasite (4) Phosphodiesterase (PDE) (1) Proteasome (1) Reference Standards (12) TNF Receptor (5) Vasopressin Receptor (1) VEGFR (5)
By Research Areas:	Cancer (4) Cardiovascular Disease (31) Endocrinology (25) Infection (5) Inflammation/Immunology (11) Neurological Disease (14)

By Targets:

5-HT Receptor (6)

Adrenergic Receptor (57)

Amyloid-β (3)

AP-1 (1)

Apoptosis (1)

Autophagy (3)

Bacterial (1)

Calcium Channel (1)

Chloride Channel (1)

Cholinesterase (ChE) (1)

Dopamine Receptor (9)

Drug Derivative (1)

Endogenous Metabolite (5)

Environmental Pollutants (1)

GABA Receptor (1)

Histamine Receptor (4)

Interleukin Related (5)

Isotope-Labeled Compounds (6)

mAChR (1)

Monoamine Oxidase (4)

NF-κB (1)

Parasite (4)

Phosphodiesterase (PDE) (1)

Proteasome (1)

Reference Standards (12)

TNF Receptor (5)

Vasopressin Receptor (1)

VEGFR (5)

By Research Areas:

Cancer (4)

Cardiovascular Disease (31)

Endocrinology (25)

Infection (5)

Inflammation/Immunology (11)

Neurological Disease (14)

Inhibitors & Agonists

Natural
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Isotope-Labeled Compounds

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0193

Prazosin Maximum Cited Publications 17 Publications Verification	Adrenergic Receptor	Cardiovascular Disease Endocrinology
Prazosin is an **α-adrenergic receptor** antagonist. Prazosin can reduce inflammation, relieve anxiety, alleviate panic, prevent memory decline, and modulate the pain-relieving effects of opioids. Prazosin can be used in the study of hypertension and Alzheimer’s disease .

HY-B0225

Methyldopa 2 Publications Verification L-(-)-α-Methyldopa; MK-351	Adrenergic Receptor Endogenous Metabolite	Cardiovascular Disease Endocrinology
Methyldopa (L-(-)-α-Methyldopa), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system .

HY-B0225B

Methyldopa hydrate 2 Publications Verification L-(-)-α-Methyldopa hydrate; MK-351 hydrate	Adrenergic Receptor Endogenous Metabolite	Cardiovascular Disease Endocrinology
Methyldopa hydrate (L-(-)-α-Methyldopa hydrate), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrate is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system .

HY-B1470

Azaperone R-1929	Dopamine Receptor Adrenergic Receptor	Neurological Disease
Azaperone is an antagonist of dopamine D2 receptor (Dopamine D2 Receptor) and α-adrenergic receptor (AR). Azaperone reduces vasomotor tone, mean arterial pressure, hematocrit, hemoglobin concentration, and etorphine-induced duration; induces transient tachycardia followed by bradycardia, splenic uptake of red blood cells, and sedation; alters animal behaviors; and produces sedation with distinct onset and duration in foals. Azaperone is used for sedation and tranquilization in various animals to reduce stress and aggressive behaviors, and serves as a preanesthetic agent .

HY-B1111

Amitraz BTS-27419	Environmental Pollutants Adrenergic Receptor Parasite Monoamine Oxidase	Infection Endocrinology
Amitraz is a non-systemic acaricide and insecticide with alpha-adrenergic agonist activity that interacts with octopamine receptors in the central nervous system and inhibits monoamine oxidase and prostaglandin synthesis .

HY-B0799

Dihydroergotoxine mesylate Ergoloid mesylates	GABA Receptor Chloride Channel Adrenergic Receptor Dopamine Receptor Phosphodiesterase (PDE)	Cardiovascular Disease Neurological Disease
Dihydroergotoxine mesylate (Ergoloid mesylates) is an *α-adrenergic* blocking agent. Dihydroergotoxine mesylate binds with high affinity to the GABA_A receptor associated Cl ^- channel. Dihydroergotoxine mesylate also interacts with central dopaminergic and serotonergic receptors. Dihydroergotoxine mesylate displays antiproliferative, antihypertensive and neuroprotective activity .Dihydroergotoxine mesylate (Ergoloid mesylates) is an *α-adrenergic* blocking agent. Dihydroergotoxine mesylate binds with high affinity to the GABA_A receptor associated Cl ^- channel. Dihydroergotoxine mesylate also interacts with central dopaminergic and serotonergic receptors. Dihydroergotoxine mesylate displays antiproliferative, antihypertensive and neuroprotective activity .

HY-B0475

Xylometazoline hydrochloride	Adrenergic Receptor	Inflammation/Immunology
Xylometazoline hydrochloride is an **α-adrenergic receptor agonist (K_i**=0.05-1.7 μM). Xylometazoline hydrochloride can constrict nasal blood vessels and increase nasal airflow. Xylometazoline hydrochloride can be used in nose stuffiness and runny nose research .

HY-A0066A

Tolazoline hydrochloride Imidaline hydrochloride; NSC35110 hydrochloride	Adrenergic Receptor	Cardiovascular Disease Endocrinology
Tolazoline hydrochloride (Imidaline hydrochloride) is an **α-adrenergic receptor** antagonist. Tolazoline hydrochloride inhibits Noradrenaline (HY-13715)-induced cell contraction, modulates vascular resistance, increases arterial pressure, and reverses bradycardia and tachypnea. Tolazoline hydrochloride can be used to study erectile dysfunction, α₂-adrenergic receptor agonist-related poisoning, and skin vascular disease research .

HY-12717A

Phentolamine hydrochloride 5+ Cited Publications	Adrenergic Receptor	Cardiovascular Disease Endocrinology
Phentolamine hydrochloride is an orally active, selective α1 and α2 Adrenergic receptor antagonist. Phentolamine hydrochloride antagonizes the vasodilatory effect of Cromakalim (HY-110011) on isolated circumflex coronary artery segments in dogs. Phentolamine hydrochloride reduces systemic vascular resistance and increases cardiac output. Phentolamine hydrochloride improves erectile dysfunction. Phentolamine hydrochloride can be used for the research of erectile dysfunction .

HY-14537

Latrepirdine dihydrochloride Dimebolin dihydrochloride	Amyloid-β Histamine Receptor Adrenergic Receptor 5-HT Receptor Autophagy	Neurological Disease Endocrinology
Latrepirdine dihydrochloride is a neuroactive compound with antagonist activity at histaminergic, α-adrenergic, and serotonergic receptors. Latrepirdine stimulates amyloid precursor protein (APP) catabolism and amyloid-β (Aβ) secretion.

HY-107915

Levonordefrin (-)-Cobefrin; (-)-α-Methylnoradrenaline; (-)-Nordefrin	Adrenergic Receptor	Cardiovascular Disease
Levonordefrin ((-)-Cobefrin; (-)-α-Methylnoradrenaline; (-)-Nordefrin) is an **α-adrenergic receptor** agonist with blood pressure regulatory properties. Levonordefrin is a key metabolite responsible for the hypotensive effect of α-methyldopa. By stimulating central α-adrenergic receptors in the nucleus tractus solitarius region of the medulla oblongata, Levonordefrin induces centrally mediated hypotension and bradycardia. When administered intravenously, Levonordefrin increases mean arterial blood pressure in a dose-dependent manner. Levonordefrin is applicable for research on the pathophysiology of hypertension and drug metabolism .

HY-A0066

Tolazoline Imidaline; NSC35110	Adrenergic Receptor	Cardiovascular Disease Endocrinology
Tolazoline (Imidaline) is an **α-adrenergic receptor** antagonist. Tolazoline inhibits Noradrenaline (HY-13715)-induced cell contraction, modulates vascular resistance, increases arterial pressure, and reverses bradycardia and tachypnea. Tolazoline can be used to study erectile dysfunction, α₂-adrenergic receptor agonist-related poisoning, and skin vascular disease research .

HY-B0446

Naphazoline hydrochloride 1 Publications Verification Naphthazoline hydrochloride	Adrenergic Receptor TNF Receptor Interleukin Related VEGFR	Cardiovascular Disease Inflammation/Immunology Cancer
Naphazoline (Naphthazoline) hydrochloride is a potent **α-adrenergic receptor** agonist. Naphazoline hydrochloride reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline hydrochloride reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. Naphazoline hydrochloride can be used for non-bacterial conjunctivitis research .

HY-111326

Naphazoline 1 Publications Verification Naphthazoline	Adrenergic Receptor TNF Receptor Interleukin Related VEGFR	Cardiovascular Disease Inflammation/Immunology Cancer
Naphazoline (Naphthazoline) is a potent **α-adrenergic receptor** agonist. Naphazoline reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. Naphazoline can be used for non-bacterial conjunctivitis research .

HY-N4225

Aaptamine 2 Publications Verification	Adrenergic Receptor Proteasome Cholinesterase (ChE) Bacterial Apoptosis AP-1 NF-κB	Infection Neurological Disease Inflammation/Immunology Endocrinology Cancer
Aaptamine is an alkaloid that can be isolated from the sponge Aaptos suberitoides. Aaptamine is a competitive antagonist of the **α-adrenergic receptor, as well as an inhibitor of the proteasome and cholinesterase. Aaptamine is cytotoxic to tumor cells and can induce apoptosis, cell cycle arrest of tumor cells, and the expression of p21** through a p53-independent pathway. Aaptamine has multiple activities such as anti-tumor, antioxidant, antibacterial, and analgesic effects .

HY-14862

Latrepirdine Dimebolin; Dimebone	Amyloid-β Histamine Receptor Adrenergic Receptor 5-HT Receptor Autophagy	Endocrinology
Latrepirdine is a neuroactive compound with antagonist activity at histaminergic, α-adrenergic, and serotonergic receptors. Latrepirdine stimulates amyloid precursor protein (APP) catabolism and amyloid-β (Aβ) secretion.

HY-B1116

Metaraminol tartrate Metaradrine tartrate	Adrenergic Receptor	Cardiovascular Disease Endocrinology
Metaraminol tartrate?(Metaradrine tartrate) is an *α-adrenergic* agonist . Metaraminol tartrate is a sympathomimetic amine that directly and indirectly affects adrenergic receptors, with alpha effects being predominant.Metaraminol tartrate acts as a vasopressor agent .

HY-B1696

Methyldopate	Adrenergic Receptor	Cardiovascular Disease
Methyldopate is an ethyl ester proagent of α-Methyldopa (α-MD; HY-B0225). Methyldopa (L-(-)-α-Methyldopa) is an α-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopate has the potential for severe hypertension research .

HY-111326A

Naphazoline nitrate 1 Publications Verification Naphthazoline nitrate	Adrenergic Receptor TNF Receptor Interleukin Related VEGFR	Cardiovascular Disease Inflammation/Immunology Cancer
Naphazoline (Naphthazoline) nitrate is an **α-adrenergic receptor** agonist. Naphazoline nitrate reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline nitrate reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. Naphazoline nitrate can be used for non-bacterial conjunctivitis research .

HY-B1111S1

Amitraz-d3 BTS-27419-d₃	Isotope-Labeled Compounds Adrenergic Receptor Monoamine Oxidase Parasite	Infection Endocrinology
Amitraz-d₃ is the deuterium labeled Amitraz. Amitraz is a non-systemic acaricide and insecticide, with alpha-adrenergic agonist activity, interaction with octopamine receptors of the central nervous system and inhibition of monoamine oxidases and prostaglandin synthesis.

HY-B0225A

Methyldopa hydrochloride L-(-)-α-Methyldopa hydrochloride; MK-351 hydrochloride	Adrenergic Receptor Endogenous Metabolite	Cardiovascular Disease Endocrinology
Methyldopa hydrochloride (L-(-)-α-Methyldopa hydrochloride) hydrochloride, a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrochloride is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system .

HY-B1111R

Amitraz (Standard) BTS-27419 (Standard)	Reference Standards Adrenergic Receptor Monoamine Oxidase Parasite	Infection Endocrinology
Amitraz (Standard) is the analytical standard of Amitraz. This product is intended for research and analytical applications. Amitraz is a non-systemic acaricide and insecticide with alpha-adrenergic agonist activity that interacts with octopamine receptors in the central nervous system and inhibits monoamine oxidase and prostaglandin synthesis.

HY-B1696A

Methyldopate hydrochloride	Adrenergic Receptor	Cardiovascular Disease
Methyldopate hydrochloride is an ethyl ester hydrochloride proagent of α-Methyldopa (α-MD; HY-B0225). Methyldopa (L-(-)-α-Methyldopa) is an α-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopate hydrochloride has the potential for severe hypertension research .

HY-W722796

Tuaminoheptane sulfate	Adrenergic Receptor	Others
Tuaminoheptane sulfate is an alpha-adrenergic *receptor* agonist. Tuaminoheptane sulfate exerts its decongestant and irritant effects by inhibiting norepinephrine reuptake and promoting its release. Tuaminoheptane sulfate can be used in research on nasal diseases such as decongestion .

HY-B0670

Dihydroergotamine DFN-19	Adrenergic Receptor 5-HT Receptor	Cardiovascular Disease Neurological Disease
Dihydroergotamine (DFN-19) is a BBB-permeable and semisynthetic, hydrogenated ergot alkaloid. Dihydroergotamine can cause vasoconstriction by stimulating *alpha-adrenergic* and 5-HT_2A receptors. Dihydroergotamine can be used in the research of migraine .

HY-B1111S

Amitraz-d6 BTS-27419-d₆	Isotope-Labeled Compounds Adrenergic Receptor Monoamine Oxidase Parasite	Infection Endocrinology
Amitraz-d6 (BTS-27419-d6) is the deuterium labeled Amitraz. Amitraz is a non-systemic acaricide and insecticide, with alpha-adrenergic agonist activity, interaction with octopamine receptors of the central nervous system and inhibition of monoamine oxidases and prostaglandin synthesis.

HY-W752502

Docarpamine	Dopamine Receptor Vasopressin Receptor Adrenergic Receptor	Cardiovascular Disease
Docarpamine is an orally active dopamine prodrug that can be hydroxylated in the small intestine and liver to form active dopamine. Docarpamine mainly activates D1-like receptors in peripheral blood vessels to lower blood pressure and heart rate in a state of spontaneous hypertension. Docarpamine exerts a pressor and tachycardic effect by activating D1-like receptors, vasopressin V1 receptors, and α-adrenergic receptors in normal blood pressure conditions. Docarpamine can be used for research on renal vascular dilation and diuresis .

HY-100255

Tiodazosin BL-5111	Adrenergic Receptor	Neurological Disease Endocrinology
Tiodazosin is a potent competitive postsynaptic **alpha adrenergic receptor** antagonist.

HY-120408

(±)-Scopolamine Atroscine	Adrenergic Receptor	Neurological Disease
(±)-Scopolamine (Atroscine) is the racemic modification of Scopolamine. (±)-Scopolamine inhibits **α-adrenergic receptor activity. (±)-Scopolamine has K_i** values of 33 μM and 7.25 nM for α₁-adrenerg receptor and muscarinic cholinergic receptor, respectively .

HY-B0475A

Xylometazoline	Adrenergic Receptor	Inflammation/Immunology
Xylometazoline is an **α-adrenergic receptor agonist (K_i**=0.05-1.7 μM). Xylometazoline can constrict nasal blood vessels and increase nasal airflow. Xylometazoline hydrochloride can be used in nose stuffiness and runny nose research .

HY-B1470S

Azaperone-d4 R-1929-d₄	Isotope-Labeled Compounds Dopamine Receptor Adrenergic Receptor	Neurological Disease
Azaperone-d₄ (R-1929-d₄) is the deuterium labeled Azaperone (HY-B1470). Azaperone is an antagonist of dopamine D2 receptor (Dopamine D2 Receptor) and α-adrenergic receptor (AR). Azaperone reduces vasomotor tone, mean arterial pressure, hematocrit, hemoglobin concentration, and etorphine-induced duration; induces transient tachycardia followed by bradycardia, splenic uptake of red blood cells, and sedation; alters animal behaviors; and produces sedation with distinct onset and duration in foals. Azaperone is used for sedation and tranquilization in various animals to reduce stress and aggressive behaviors, and serves as a preanesthetic agent.

HY-14560A

(R,R)-Reboxetine mesylate (R,R)-FCE20124 mesylate; (R,R)-PNU155950E mesylate; (R,R)-(-)-Reboxetine mesylate	Adrenergic Receptor mAChR	Neurological Disease
(R,R)-Reboxetine mesylate is an antidepressant agent with great bioavailability. (R,R)-Reboxetine is the enantiomer of Reboxetine, which is a selective noradrenaline reuptake inhibitor. Reboxetine consists of (R,R) and (S,S) enantiomer, has low affinity for *alpha-adrenergic* and muscarinic receptors and low toxicity in animals .

HY-B0225AS

Methyldopa-d3 hydrochloride L-(-)-α-Methyldopa-d3 hydrochloride; MK-351-d3 hydrochloride	Isotope-Labeled Compounds Adrenergic Receptor Endogenous Metabolite	Cardiovascular Disease Endocrinology
Methyldopa-d₃ (hydrochloride) is deuterium labeled Methyldopa (hydrochloride). Methyldopa hydrochloride (L-(-)-α-Methyldopa hydrochloride) hydrochloride, a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrochloride is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system .

HY-B0225BR

Methyldopa hydrate (Standard) L-(-)-α-Methyldopa hydrate (Standard); MK-351 hydrate (Standard)	Reference Standards Adrenergic Receptor Endogenous Metabolite	Cardiovascular Disease Endocrinology
Methyldopa (hydrate) (Standard) is the analytical standard of Methyldopa (hydrate). This product is intended for research and analytical applications. Methyldopa hydrate (L-(-)-α-Methyldopa hydrate), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrate is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system .

HY-U00313

Tropodifene Tropaphen	Adrenergic Receptor	Cardiovascular Disease Endocrinology
Tropodifene (Tropaphen) is an **α-Adrenergic receptor** inhibitor.

HY-117063

LEK 8841 methanesulfonate	5-HT Receptor	Endocrinology
LEK 8841 methanesulfonate is a gastrointestinal calming agent with strong selective 5-HT2 receptor antagonist activity. The antipsychotic potential of LEK 8841 has made it the focus of research into alternative medicines. LEK 8841 behaves as a pure competitive antagonist in response to 5-HT and norepinephrine, with pA2 values of 7.93 and 6.45, respectively. The selectivity of LEK 8841 is better than that of the comparative drug ketanserin, making it an important reference value in corresponding receptor research. Studies related to structural modifications have shown that LEK 8841 exhibits high affinity for 5-HT2 receptors and low alpha-adrenergic receptor activity .

HY-126635

Mafoprazine	Dopamine Receptor Adrenergic Receptor	Others
Mafoprazine is a phenylpiperazine derivative with variable affinities for neuronal receptors. It may exert its antipsychotic effects primarily through D2 receptor blockade and α-adrenergic activity, and may increase the activity of dopamine metabolites.

HY-107915R

Levonordefrin (Standard) (-)-Cobefrin (Standard); (-)-α-Methylnoradrenaline (Standard); (-)-Nordefrin (Standard)	Reference Standards Adrenergic Receptor	Others
Levonordefrin (Standard) is the analytical standard of Levonordefrin. This product is intended for research and analytical applications. Levonordefrin ((-)-Cobefrin; (-)-α-Methylnoradrenaline; (-)-Nordefrin) is an **α-adrenergic receptor** agonist with blood pressure regulatory properties. Levonordefrin is a key metabolite responsible for the hypotensive effect of α-methyldopa. By stimulating central α-adrenergic receptors in the nucleus tractus solitarius region of the medulla oblongata, Levonordefrin induces centrally mediated hypotension and bradycardia. When administered intravenously, Levonordefrin increases mean arterial blood pressure in a dose-dependent manner. Levonordefrin is applicable for research on the pathophysiology of hypertension and drug metabolism .

HY-126635R

Mafoprazine (Standard)	Adrenergic Receptor Dopamine Receptor Reference Standards	Others
Mafoprazine (Standard) is the analytical standard of Mafoprazine. This product is intended for research and analytical applications. Mafoprazine is a phenylpiperazine derivative with variable affinities for neuronal receptors. It may exert its antipsychotic effects primarily through D2 receptor blockade and α-adrenergic activity, and may increase the activity of dopamine metabolites.

HY-14537R

Latrepirdine dihydrochloride (Standard) Dimebolin dihydrochloride (Standard)	Amyloid-β Histamine Receptor Adrenergic Receptor 5-HT Receptor Autophagy Reference Standards	Neurological Disease Endocrinology
Latrepirdine (dihydrochloride) (Standard) is the analytical standard of Latrepirdine (dihydrochloride). This product is intended for research and analytical applications. Latrepirdine dihydrochloride is a neuroactive compound with antagonist activity at histaminergic, α-adrenergic, and serotonergic receptors. Latrepirdine stimulates amyloid precursor protein (APP) catabolism and amyloid-β (Aβ) secretion.

HY-133214

Cyclazosin hydrochloride	Adrenergic Receptor	Cardiovascular Disease
Cyclazosin hydrochloride is an α_1B-adrenergic *receptor* antagonist. Cyclazosin hydrochloride has high specificity for α-adrenergic receptors, with pK_i values of 9.23-9.57 and 8.18-8.41 for O/1A (O/la) and OflB (alb) adrenergic receptors, respectively. However, Cyclazosin hydrochloride cannot distinguish between cloned alb and alo adrenergic receptors, which have pK_i values of 9.23 and 9.28, respectively .

HY-B1116R

Metaraminol tartrate (Standard) Metaradrine tartrate (Standard)	Reference Standards Adrenergic Receptor	Cardiovascular Disease Endocrinology
Metaraminol (tartrate) (Standard) is the analytical standard of Metaraminol (tartrate). This product is intended for research and analytical applications. Metaraminol tartrate?(Metaradrine tartrate) is an α-adrenergic agonist . Metaraminol tartrate is a sympathomimetic amine that directly and indirectly affects adrenergic receptors, with alpha effects being predominant.Metaraminol tartrate acts as a vasopressor agent .

HY-B0475S

Xylometazoline-d4 hydrochloride	Adrenergic Receptor Isotope-Labeled Compounds	Inflammation/Immunology
Xylometazoline-d₄ hydrochloride is deuterated labeled Xylometazoline hydrochloride (HY-B0475). Xylometazoline hydrochloride is an **α-adrenergic receptor agonist (K_i**=0.05-1.7 μM). Xylometazoline hydrochloride can constrict nasal blood vessels and increase nasal airflow. Xylometazoline hydrochloride can be used in nose stuffiness and runny nose research .

HY-B0475R

Xylometazoline hydrochloride (Standard)	Reference Standards Adrenergic Receptor	Inflammation/Immunology
Xylometazoline (hydrochloride) (Standard) is the analytical standard of Xylometazoline (hydrochloride). This product is intended for research and analytical applications. Xylometazoline hydrochloride is an **α-adrenergic receptor agonist (K_i**=0.05-1.7 μM). Xylometazoline hydrochloride can constrict nasal blood vessels and increase nasal airflow. Xylometazoline hydrochloride can be used in nose stuffiness and runny nose research .

HY-101390

(+)-Niguldipine hydrochloride (S)-Niguldipine hydrochloride	Calcium Channel Adrenergic Receptor	Cardiovascular Disease
(+)-Niguldipine hydrochloride is a 1,4-DHP receptor ligand associated with L-type Ca ²⁺ channels (with K_i values of 85 pmol/L in guinea pig skeletal muscle, 140 pmol/L in brain, and 45 pmol/L in heart) as well as an **α₁-adrenergic receptor ligand (with a K_i value of 78 nmol/L). (+)-Niguldipine hydrochloride shows much higher binding selectivity for α_1α-**adrenergic receptors than for *α_1B-*adrenergic receptors. (+)-Niguldipine hydrochloride can be used in studies related to hypertension .

HY-A0066R

Tolazoline (Standard) Imidaline (Standard); NSC35110 (Standard)	Adrenergic Receptor Reference Standards	Cardiovascular Disease Endocrinology
Tolazoline (Standard) is the analytical standard of Tolazoline. This product is intended for research and analytical applications. Tolazoline (Imidaline) is an α-adrenergic receptor antagonist. Tolazoline inhibits Noradrenaline (HY-13715)-induced cell contraction, modulates vascular resistance, increases arterial pressure, and reverses bradycardia and tachypnea. Tolazoline can be used to study erectile dysfunction, α2-adrenergic receptor agonist-related poisoning, and skin vascular disease research .

HY-B1470R

Azaperone (Standard) R-1929 (Standard)	Reference Standards Dopamine Receptor Adrenergic Receptor	Neurological Disease
Azaperone (R-1929) (Standard) is the analytical standard of Azaperone (HY-B1470). This product is intended for research and analytical applications. Azaperone is an antagonist of dopamine D2 receptor (Dopamine D2 Receptor) and α-adrenergic receptor (AR). Azaperone reduces vasomotor tone, mean arterial pressure, hematocrit, hemoglobin concentration, and etorphine-induced duration; induces transient tachycardia followed by bradycardia, splenic uptake of red blood cells, and sedation; alters animal behaviors; and produces sedation with distinct onset and duration in foals. Azaperone is used for sedation and tranquilization in various animals to reduce stress and aggressive behaviors, and serves as a preanesthetic agent.

HY-A0066AR

Tolazoline hydrochloride (Standard) Imidaline hydrochloride (Standard); NSC35110 hydrochloride (Standard)	Reference Standards Adrenergic Receptor	Cardiovascular Disease Endocrinology
Tolazoline (hydrochloride) (Standard) is the analytical standard of Tolazoline hydrochloride (HY-A0066A). This product is intended for research and analytical applications. Tolazoline hydrochloride (Imidaline hydrochloride) is an **α-adrenergic receptor** antagonist. Tolazoline hydrochloride inhibits Noradrenaline (HY-13715)-induced cell contraction, modulates vascular resistance, increases arterial pressure, and reverses bradycardia and tachypnea. Tolazoline hydrochloride can be used to study erectile dysfunction, α₂-adrenergic receptor agonist-related poisoning, and skin vascular disease research .

HY-B0446R

Naphazoline hydrochloride (Standard) Naphthazoline hydrochloride (Standard)	Reference Standards Adrenergic Receptor TNF Receptor Interleukin Related VEGFR	Cardiovascular Disease Inflammation/Immunology
Naphazoline (hydrochloride) (Standard) is the analytical standard of Naphazoline (hydrochloride). This product is intended for research and analytical applications. Naphazoline (Naphthazoline) hydrochloride is a potent **α-adrenergic receptor** agonist. Naphazoline hydrochloride reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline hydrochloride reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF。Naphazoline hydrochloride can be used for non-bacterial conjunctivitis research .

HY-111326AR

Naphazoline nitrate (Standard) Naphthazoline nitrate (Standard)	Reference Standards Adrenergic Receptor TNF Receptor Interleukin Related VEGFR	Cardiovascular Disease Inflammation/Immunology
Naphazoline (nitrate) (Standard) is the analytical standard of Naphazoline (nitrate). This product is intended for research and analytical applications. Naphazoline (Naphthazoline) nitrate is an α-adrenergic receptor agonist. Naphazoline nitrate reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline nitrate reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. Naphazoline nitrate can be used for non-bacterial conjunctivitis research .

Cat. No.	Product Name	Chemical Structure

HY-B1111S1

Amitraz-d3
Amitraz-d₃ is the deuterium labeled Amitraz. Amitraz is a non-systemic acaricide and insecticide, with alpha-adrenergic agonist activity, interaction with octopamine receptors of the central nervous system and inhibition of monoamine oxidases and prostaglandin synthesis.

HY-B1111S

Amitraz-d6
Amitraz-d6 (BTS-27419-d6) is the deuterium labeled Amitraz. Amitraz is a non-systemic acaricide and insecticide, with alpha-adrenergic agonist activity, interaction with octopamine receptors of the central nervous system and inhibition of monoamine oxidases and prostaglandin synthesis.

HY-B1470S

Azaperone-d4

Azaperone-d₄ (R-1929-d₄) is the deuterium labeled Azaperone (HY-B1470). Azaperone is an antagonist of dopamine D2 receptor (Dopamine D2 Receptor) and α-adrenergic receptor (AR). Azaperone reduces vasomotor tone, mean arterial pressure, hematocrit, hemoglobin concentration, and etorphine-induced duration; induces transient tachycardia followed by bradycardia, splenic uptake of red blood cells, and sedation; alters animal behaviors; and produces sedation with distinct onset and duration in foals. Azaperone is used for sedation and tranquilization in various animals to reduce stress and aggressive behaviors, and serves as a preanesthetic agent.

HY-B0225AS

Methyldopa-d3 hydrochloride
Methyldopa-d₃ (hydrochloride) is deuterium labeled Methyldopa (hydrochloride). Methyldopa hydrochloride (L-(-)-α-Methyldopa hydrochloride) hydrochloride, a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrochloride is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system .

HY-B0475S

Xylometazoline-d4 hydrochloride
Xylometazoline-d₄ hydrochloride is deuterated labeled Xylometazoline hydrochloride (HY-B0475). Xylometazoline hydrochloride is an **α-adrenergic receptor agonist (K_i**=0.05-1.7 μM). Xylometazoline hydrochloride can constrict nasal blood vessels and increase nasal airflow. Xylometazoline hydrochloride can be used in nose stuffiness and runny nose research .

HY-A0027S

Fenspiride-d5 hydrochloride
Fenspiride-d₅ hydrochloride is the deuterium labeled Fenspiride hydrochloride (HY-A0027). Fenspiride hydrochloride is an α adrenergic and H1 histamine receptor antagonist .

Host:	Rabbit (2)
Reactivity:	Human (2) Rat (2) Mouse (2)
Application:	IHC-P (2) ICC/IF (2) WB (2) FC (2)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (2)
Clonality:	Monoclonal (1) Recombinant (1)
Modification:	Unmodified (1)

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HY-P82314

	alpha 1a Adrenergic Receptor Antibody (YA2059) ADRA1A; ADRA1C; alpha-1A adrenergic receptor; alpha-1A adrenoreceptor; alpha-1A adrenoceptor; alpha-1C adrenergic receptor; alpha-adrenergic receptor 1c	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	alpha 1a Adrenergic Receptor Antibody (YA2059) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to alpha 1a Adrenergic Receptor.

HY-P82314A

	alpha 1a Adrenergic Receptor Antibody (YA2059)(PBS only) ADRA1A; ADRA1C; alpha-1A adrenergic receptor; alpha-1A adrenoreceptor; alpha-1A adrenoceptor; alpha-1C adrenergic receptor; alpha-adrenergic receptor 1c	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	alpha 1a Adrenergic Receptor Antibody (YA2059) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to alpha 1a Adrenergic Receptor.

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