120 Results for "

anti-metastatic

" in MedChemExpress (MCE) Product Catalog:
Products (120)

120 Results for "anti-metastatic" in MCE Product Catalog:

25
25 Publications Verification
Cat. No.: HY-B0617
CAS No.: 29908-03-0
Synonyms: S-Adenosyl methionine; Ademetionine; AdoMet
S-Adenosyl-L-methionine (S-Adenosyl methionine) is an orally active methyl group donor. S-Adenosyl-L-methionine is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine has the potential for, cancer, liver disease and osteoarthritis research .
loading...
    loading...
24
24 Cited Publications
Cat. No.: HY-W017770
CAS No.: 97540-22-2
Synonyms: Ademetionine disulfate tosylate; S-Adenosyl methionine disulfate tosylate; AdoMet disulfate tosylate
S-Adenosyl-L-methionine (Ademetionine) disulfate tosylate is the disulfate tosylate form of S-Adenosyl-L-methionine (HY-B0617). S-Adenosyl-L-methionine disulfate tosylate is an orally active methyl group donor. S-Adenosyl-L-methionine disulfate tosylate is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine disulfate tosylate also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine disulfate tosylate has the potential for, cancer, liver disease and osteoarthritis research .
loading...
    loading...
23
23 Cited Publications
Cat. No.: HY-B0617A
CAS No.: 52248-03-0
Synonyms: S-Adenosyl methionine tosylate; Ademetionine tosylate; AdoMet tosylate
S-Adenosyl-L-methionine (S-Adenosyl methionine) tosylate is an orally active methyl group donor. S-Adenosyl-L-methionine tosylate is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine tosylate also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine tosylate has the potential for, cancer, liver disease and osteoarthritis research .
loading...
    loading...
19
19 Cited Publications
Cat. No.: HY-14614D
CAS No.: 3493-13-8
Synonyms: S-Adenosyl methionine iodide; Ademetionine iodide; AdoMet iodide
S-Adenosyl-L-methionine (S-Adenosyl methionine) iodide is an orally active methyl group donor. S-Adenosyl-L-methionine iodide is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine iodide also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine iodide has the potential for, cancer, liver disease and osteoarthritis research .
loading...
    loading...
14
14 Cited Publications
Cat. No.: HY-16929
CAS No.: 76343-93-6
Synonyms: LAT-A
Latrunculin A (LAT-A), found in the red sea sponge Latrunculia magnifica, is a G-actin polymerization inhibitor. Latrunculin A binds to actin monomers and inhibits polymerization of actin with Kds of 0.1, 0.4, 4.7 μM and 0.19 μM for ATP-actin, ADP-Pi-actin, ADP-actin and G-actin, respectively. Latrunculin A has effective anti-metastatic properties for cancer research. Latrunculin A blocks cell migration .
loading...
    loading...
14
14 Cited Publications
Cat. No.: HY-123071
CAS No.: 1206604-29-6
Purity:  99.24%
Target:  

Wnt

Research Areas:  

Cancer

Box5 is a potent Wnt5a antagonist. Box5 inhibits Wnt5a signaling and inhibits Wnt5a-mediated Ca 2+ release. Box5 inhibits cell migration. Box5 has the potential for the research of melanoma .
loading...
    loading...
14
14 Cited Publications
Cat. No.: HY-103021
CAS No.: 1898283-02-7
Purity:  99.87%
Target:  

TGF-β Receptor

Research Areas:  

Inflammation/Immunology Cancer

LY3200882 is a potent, highly selective, ATP-competitive and orally active TGF-β receptor type 1 (ALK5) inhibitor with an IC50 of 38.2 nM. LY3200882 inhibits various pro-tumorigenic activities and is also used as an immune modulatory agent .
loading...
    loading...
14
14 Cited Publications
Cat. No.: HY-123071A
Purity:  99.24%
Target:  

Wnt

Research Areas:  

Cancer

Box5 TFA is a potent Wnt5a antagonist. Box5 TFA inhibits Wnt5a signaling and inhibits Wnt5a-mediated Ca 2+ release. Box5 TFA inhibits cell migration. Box5 TFA has the potential for the research of melanoma .
loading...
    loading...
13
13 Cited Publications
Cat. No.: HY-19928
CAS No.: 1352608-82-2
Synonyms: EW-7197; TEW-7197
Target:  

TGF-β Receptor

Research Areas:  

Cancer

Vactosertib (EW-7197) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC50 of 12.9 nM. Vactosertib also inhibits ALK2 and ALK4 (IC50 of 17.3 nM) at nanomolar concentrations. Vactosertib has potently antimetastatic activity and anticancer effect .
loading...
    loading...
13
13 Cited Publications
Cat. No.: HY-19928A
CAS No.: 1352610-25-3
Synonyms: EW-7197 Hydrochloride; TEW-7197 Hydrochloride
Target:  

TGF-β Receptor

Research Areas:  

Cancer

Vactosertib Hydrochloride (EW-7197 Hydrochloride) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC50 of 12.9 nM. Vactosertib Hydrochloride also inhibits ALK2 and ALK4 (IC50 of 17.3 nM) at nanomolar concentrations. Vactosertib Hydrochloride has potently antimetastatic activity and anticancer effect .
loading...
    loading...
12
12 Cited Publications
Cat. No.: HY-14614A
CAS No.: 86867-01-8
Purity:  ≥75.0%
Synonyms: S-Adenosyl methionine chloride dihydrochloride; Ademetionine chloride dihydrochloride; AdoMet chloride dihydrochloride
S-Adenosyl-L-methionine (S-Adenosyl methionine) chloride dihydrochloride is an orally active methyl group donor. S-Adenosyl-L-methionine chloride dihydrochloride is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine chloride dihydrochloride also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine chloride dihydrochloride has the potential for, cancer, liver disease and osteoarthritis research .
loading...
    loading...
9
9 Cited Publications
Cat. No.: HY-N0187
CAS No.: 90-33-5
Synonyms: Hymecromone; 4-MU
4-Methylumbelliferone is a hyaluronic acid biosynthesis inhibitor with antitumoral and antimetastatic effects.
loading...
    loading...
9
9 Cited Publications
Cat. No.: HY-135232
CAS No.: 502887-71-0
Purity:  99.82%
Target:  

MMP

Research Areas:  

Cancer

MMP-9-IN-1 is a specific matrix metalloproteinase-9 (MMP-9) inhibitor, which selectively target the hemopexin (PEX) domain of MMP-9, but not other MMPs .
loading...
    loading...
9
9 Cited Publications
Cat. No.: HY-104064
CAS No.: 1430208-73-3
Purity:  99.72%
Target:  

Ras Apoptosis

Research Areas:  

Cancer

1A-116, a potent Rac1 inhibitor, is specific for W56 residues, can prevent EGF-induced Rac1 activation and block Rac1-P-Rex1 interaction. 1A-116 can induce apoptosis and inhibit cell proliferation, migration and cycle progression in a concentration-dependent manner. 1A-116 also demonstrates a high antimetastatic activity in vivo .
loading...
    loading...
7
7 Cited Publications
Cat. No.: HY-P1416
CAS No.: 881188-51-8
Target:  

Wnt

Research Areas:  

Cancer

Foxy-5, a WNT5A agonist, is a mimicking peptide of WNT5A which is a non-canonical member of the Wnt family. Foxy-5 triggers cytosolic free calcium signaling without affecting β-catenin activation and it impairs the migration and invasion of epithelial cancer cells. Foxy-5 effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model .
loading...
    loading...
7
7 Cited Publications
Cat. No.: HY-P1416A
Target:  

Wnt

Research Areas:  

Cancer

Foxy-5 TFA, a WNT5A agonist, is a mimicking peptide of WNT5A which is a non-canonical member of the Wnt family. Foxy-5 TFA triggers cytosolic free calcium signaling without affecting β-catenin activation and it impairs the migration and invasion of epithelial cancer cells. Foxy-5 TFA effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model .
loading...
    loading...
6
6 Cited Publications
Cat. No.: HY-N2022
CAS No.: 79831-76-8
Castanospermine is a natural alkaloid that can be extracted from black beans or the Moreton Bay chestnut tree (Castanospermum australae). Castanospermine is an α/ β-glucosidase inhibitor. Castanospermine has anti-inflammatory, antiviral replication and anti-metastatic effects on prostate cancer. Castanospermine can be used as an immunosuppressant to prevent transplant rejection .
loading...
    loading...
6
6 Cited Publications
Cat. No.: HY-A0096
CAS No.: 78919-13-8
Synonyms: Ciloprost; ZK 36374
Iloprost (ZK 36374; Ciloprost) is a prostacyclin (PGI2) analogue, involves in embryo development and inflammation improvement, and inhibits tumor metastasis. Iloprost can be used for peripheral vascular research .
loading...
    loading...
5
5 Cited Publications
Cat. No.: HY-N1376
CAS No.: 38243-03-7
Synonyms: (20R)-Propanaxadiol; R-ginsenoside Rg3
(20R)-ginsenoside Rg3 ((20R)-Propanaxadiol), one of the active compounds present in ginseng root, inhibits angiogenesis, and has anti-carcinogenic and antimetastatic effects .
loading...
    loading...
5
5 Cited Publications
Cat. No.: HY-N0579
CAS No.: 524-30-1
Synonyms: Fraxoside
Fraxin isolated from Cortex Fraxini, is a glucoside of fraxetin and reported to exert potent anti-oxidative stress action , anti-inflammatory and antimetastatic properties. Fraxin shows its antioxidative effect through inhibition of cyclo AMP phosphodiesterase enzyme .
loading...
    loading...