36 Results for "

astragalus

" in MedChemExpress (MCE) Product Catalog:
Products (36)

36 Results for "astragalus" in MCE Product Catalog:

43
43 Publications Verification
Cat. No.: HY-N0431
CAS No.: 84687-43-4
Astragaloside IV, an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells.
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2 Cited Publications
Cat. No.: HY-N0433
CAS No.: 84676-89-1
Synonyms: Astrasieversianin VIII
Astragaloside II is an orally active Cycloartane-type triterpene glycoside. Astragaloside II can be extracted from Astragalus membranaceus. Astragaloside II inhibits Autophagy, decreases pro-inflammatory cytokines (IL-6, IL-1β), HIF-α, p-p65, p-IκB and increases SOD. Astragaloside II regulates immunity and reduces inflammatory responses. Astragaloside II can be used in the research of diseases such as liver cancer, osteoporosis, immunosuppressive diseases, and ulcerative colitis .
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2 Cited Publications
Cat. No.: HY-N0434
CAS No.: 84687-42-3
Astragaloside III is a triterpenoid saponin. Astragaloside III can be extracted from Astragalus root. Astragaloside III increases NKG2D and induces TACE phosphorylation. Astragaloside III induces Apoptosis. Astragaloside III has antiviral activity against dengue serotypes 1 and 3. Astragaloside III has anticancer activity against breast and colon cancer .
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2 Cited Publications
Cat. No.: HY-N2473
CAS No.: 94367-42-7
Methylnissolin-3-O-glucoside is a flavonoid glycoside derivative of Methylnissolin (HY-N2484). Methylnissolin-3-O-glucoside is isolated from plants of the genus Astragalus (Leguminosae). Methylnissolin-3-O-glucoside effectively induces the expression of AKT/Nrf2 and its downstream target genes HO-1 and NQO1. Methylnissolin-3-O-glucoside inhibits TNF-α-induced phosphorylation of MEK and ERK . Methylnissolin-3-O-glucoside exhibits free radical scavenging activity. Methylnissolin-3-O-glucoside inhibits cell proliferation and cell migration. Methylnissolin-3-O-glucoside is used in research on esophageal squamous cell carcinoma .
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2 Cited Publications
Cat. No.: HY-N0887
CAS No.: 84676-88-0
Synonyms: Isoastragaloside-I
Isoastragaloside I is a natural compound found in Astragalus membranaceus, with oral activity and multiple biological activities such as anti-inflammatory and antioxidant properties. Isoastragaloside I inhibits Akt, NF-κB, MAPKs and PI3K, enhances the activity of hepatic FXR, regulates the TGF-β/Smads signaling pathway, and upregulates antioxidant molecules downstream of Nrf2. Isoastragaloside I inhibits the expression of NO, TNF-α, iNOS, COX-2, IL-1β and VCAM-1, and reduces intracellular ROS levels. Isoastragaloside I attenuates blood-brain barrier disruption, restores intestinal barrier function, increases β-cell mass, improves glucose homeostasis, and elevates circulating adiponectin levels. Isoastragaloside I can be used for the study of neuroinflammation-related neurodegenerative diseases, cholestatic liver disease, and diabetes .
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Cat. No.: HY-N0432
CAS No.: 84680-75-1
Synonyms: Astrasieversianin IV; Cyclosieversioside B
Astragaloside I, one of the main active ingredients in Astragalus membranaceus, has osteogenic properties. Astragaloside I stimulates osteoblast differentiation through activating the Wnt/β-catenin signaling pathway .
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Cat. No.: HY-159066
Purity:  70.29%
Polysachoride of astragalus mongholicus is an astragalus polysaccharide that can be isolated from Astragalus Mongholicus, exhibits antifibrotic activity .
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Cat. No.: HY-N0431R
CAS No.: 84687-43-4
Astragaloside IV (Standard) is the analytical standard of Astragaloside IV. This product is intended for research and analytical applications. Astragaloside IV, an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells.
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Cat. No.: HY-N0424
CAS No.: 84605-18-5
Synonyms: Cyclogalegigenin
Cyclogalegenin (Cyclogalegigenin) is an isoprenoid. Cyclogalegenin can be isolated from Astragalus galegiformis. Cyclogalegenin is an isomer of cycloastragenol.
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Cat. No.: HY-N4005
CAS No.: 54081-48-0
Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) with an IC50 value of 54.3 μg/mL, and also inhibits tyrosinase activity. Isoastilbin shows neuroprotective, antioxidation, antimicrobial and anti-apoptotic properties and has the potential for Alzheimer’s disease research .
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Cat. No.: HY-W250121
CAS No.: 9000-65-1
Tragacanth gum is an orally active anionic composite polysaccharide and multifunctional biomaterial. Tragacanth gum exhibits biocompatibility, mucoadhesion and renoprotective effects, and effectively promotes wound closure and tissue healing. Tragacanth gum can be isolated from Astragalus gummifer. Tragacanth gum acts as an emulsifier and drug delivery carrier, and is also widely used in fields such as 3D scaffolds, tissue engineering and green nanoparticle preparation. High doses of Tragacanth gum may induce reversible forestomach squamous epithelial hyperplasia in mice, but show no mutagenic or carcinogenic activity. Tragacanth gum is commonly used in studies related to diseases including systemic candidiasis, rheumatoid arthritis and osteosarcoma .
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Cat. No.: HY-N0888
CAS No.: 86764-11-6
Synonyms: Astrasieversianin-VII
Isoastragaloside II is an astragaloside, which is isolated from the hairy root culture of Astragalus membranaceus.
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Cat. No.: HY-N9989
CAS No.: 86764-12-7
Brachyoside B is a triterpenoid saponin from Astragalus wiedemannianus .
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Cat. No.: HY-N11472
CAS No.: 41545-37-3
Synonyms: Rhamnocitrin-3-O-β-D-glucopyranoside
Rhamnocitrin 3-glucoside (Rhamnocitrin-3-O-β-D-glucopyranoside) is a natural product that can be isolated from Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsiao (AM) .
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Cat. No.: HY-N12954
CAS No.: 57128-11-7
(R)-Mucronulatol is a flavonoid that can be isolated from Astragalus adsurgens. (R)-Mucronulatol shows antibacterial activity against Escherichia coli, Bacillus cereus, Staphylococcus aureus, Erwinia carotovora and Bacillus subtili, with MICs of 15.5, 15.5, 7.8, 7.8, 15.5 μg/mL respectively .
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Cat. No.: HY-N10048
CAS No.: 156769-94-7
Agroastragaloside I is a astragaloside, and can be isolated from the hairy root cultures of Astragalus membranaceus .
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Cat. No.: HY-N9880
CAS No.: 27542-39-8
Tamarixin is flavonoid that isolated from Astragalus tanae Sosn that has hepatoprotective, antioxidant, anticancer, and antimicrobial activities .
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Cat. No.: HY-N0624
CAS No.: 146501-37-3
Complanatoside A is a flavonol glycoside isolated from Astragalus complanatus, and currently it is used as a quality control index for A. complanatus in the 2010 edition of the Chinese Pharmacopoeia.
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Cat. No.: HY-131300
CAS No.: 477-29-2
Purity:  99.37%
Colchicoside is a monoglycosylated colchicine alkaloid glycoside with anti-leishmanial activity. Colchicoside can be obtained by specific glycosylation of Colchicine (HY-16569) by Astragalus vesicarius plant suspension cells, and is also found in Gloriosa superba seeds. Colchicoside can serve as a precursor for the synthesis of Thiocolchicoside (HY-N0301). Colchicoside can be used in research related to anti-leishmanial infection .
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Cat. No.: HY-N6250
CAS No.: 136087-29-1
Synonyms: Isomucronulatol 7-O-β-glucoside
Isomucronulatol 7-O-glucoside (Isomucronulatol 7-O-β-D-glucoside) is an isoflavonoid glycoside isolated from the roots of Astragalus membranaceus. Isomucronulatol 7-O-glucoside targets inflammation-related pathways in vitro to exert anti-inflammatory activity without cytotoxicity at effective concentrations. Isomucucronulatol 7-O-glucoside inhibits NO production and weakly suppresses IL‑12 p40 production in vitro. Isomucronulatol 7-O-glucoside can be used for the research on inflammation .
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