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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
cleavable probe
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "cleavable probe" in MCE Product Catalog:
17
17 Cited Publications
Cat. No.: HY-D0717
CAS No.: 254109-22-3
Synonyms: Diaminofluorescein-FM diacetate
12
Cat. No.: HY-DY1046
CAS No.: 136832-63-8
Solvent and concentration: DMSO: 10 mM
Cat. No.: HY-D1078
CAS No.: 127770-45-0
Cat. No.: HY-149931
CAS No.: 1458731-58-2
Target:
Research Areas:
BMV109 is a quenched probe that becomes fluorescent when cleaved and covalently bound by active cathepsin proteases. BMV109 can be exploited for tumor imaging .
Cat. No.: HY-DY1048
CAS No.: 254109-22-3
Solvent and concentration: DMSO: 2 mM
Cat. No.: HY-112526
CAS No.: 1004324-99-5
Cat. No.: HY-155486
Target:
Research Areas:
HCy-AAN-Bio is a tumor-targeted hemicyanine (HCy) probe for Fluorescent/photoacoustic (FL/PA) imaging of legumain in vivo. Legumain can specifically cleave HCy-AAN-Bio with the generation of FL/PA signal. HCy-AAN-Bio is a powerful tool for early diagnosis of associated cancer .
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Research Areas:
Deg-1 is a a bifunctional probe with a cleavage group and a covalent binding group. Deg-1 covalently binds to the target nucleic acid, and serves as click-degrader to cleave a nucleic acid molecule. Deg-1 has potential to selectively cleave target nucleic acids in cells . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
Cat. No.: HY-W411215
CAS No.: 83619-73-2
Cat. No.: HY-D2943
Synonyms: SNAP-SS-SulfoCy3
Cat. No.: HY-D2930
Synonyms: SNAP-SS-SulfoCy5
Cat. No.: HY-D3319
Cat. No.: HY-P11595
CAS No.: 2357123-44-3
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Research Areas:
Cat. No.: HY-175163
Target:
Research Areas:
TPAPyN is a nitroreductase(NTR)-responsive type I photosensitizer. TPAPyN facilitates the imaging of hypoxic cancer cells and image-guided photodynamic therapy (PDT). TPAPyN does not emit fluorescence in the aqueous environment, but restores when NTR cleaves the nitrofuran quencher with aggregation-induced emission. TPAPyN can be used as a fluorescent probe for specific imaging of hypoxic cancer .
Cat. No.: HY-156898
Research Areas:
NPT100-18A is an αSyn oligomerization inhibitor. NPT10018A rescues cleaved caspase-3 levels to control levels. NPT10018A attenuates mitochondrial oxidative stress probe levels in a compartment-specific manner and, at higher concentrations, increases ATP signals. NPT100-18A can be used for the study of Parkinson’s disease (PD) .
Cat. No.: HY-D3169
CAS No.: 1476735-95-1
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Research Areas:
Cat. No.: HY-D2924
Cat. No.: HY-D3187
CAS No.: 2484831-02-7
Cat. No.: HY-D3181
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
