47 Results for "

exposure biomarker

" in MedChemExpress (MCE) Product Catalog:
Products (47)

47 Results for "exposure biomarker" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-B1178
CAS No.: 486-56-6
Synonyms: (-)-Cotinine; (S)-Cotinine; NIH-10498
Cotinine ((-)-Cotinine) is an orally active alkaloid found in tobacco and is the primary metabolite of nicotine. Cotinine is metabolized by CYP2A13 into trans-3'-hydroxycotinine. Cotinine is used as a biomarker to measure exposure to tobacco smoke components. Cotinine has vasodepressor activity. The mixture of cotinine and nicotine (Nicotine) has antiproliferative activity against pterygium. (S)-(-)-Cotinine activates nicotinic acetylcholine receptors (nAChR) in a calcium-dependent manner, leading to the release of dopamine (Dopamine, HY-B0451). Cotinine ((-)-Cotinine) is used in research related to cardiovascular and inflammatory diseases .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-113266
CAS No.: 40225-14-7
Purity:  ≥95.0%
Valerylcarnitine is an endogenous metabolite, belonging to the short-chain acylcarnitines. Valerylcarnitine acts as a metabolomic biomarker for ionizing radiation exposure in nonhuman primates. Valerylcarnitine can be used for the research of type 1 diabetes .
loading...
    loading...
Cat. No.: HY-136924
CAS No.: 259270-28-5
Purity:  99.84%
Target:  

FAAH

Research Areas:  

Others

FP-biotin is a potent organophosphorus toxicant, well-suited for searching for new biomarkers of organophosphorus toxicants exposure. FP-Biotin quantifies FAAH, ABHD6, and MAG-lipase activity. FP-biotin is used for studies with plasma because biotinylated peptides are readily purified by binding to immobilized avidin beads .
loading...
    loading...
Cat. No.: HY-113093
CAS No.: 17685-04-0
Purity:  98.39%
Ethyl glucuronide is an endogenous metabolite. Ethyl glucuronide is the metabolite of ethanol. Ethyl glucuronide is a biomarker for ethanol exposure that accumulates in hair and reflects the alcohol intake over a time period. Ethyl glucuronide is the agonist for TLR4 .
loading...
    loading...
Cat. No.: HY-133677
CAS No.: 40321-99-1
Purity:  99.03%
Synonyms: MEHHP
Research Areas:  

Cancer

Mono (2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) is a biomarker for human exposure to DEHP (HY-B1945). By activating the tryptophan-kynurenine-aryl hydrocarbon receptor (AhR) pathway, mono (2-ethyl-5-hydroxyhexyl) phthalate significantly increases the viability of primary uterine leiomyoma cells and reduces cell apoptosis. Mono (2-ethyl-5-hydroxyhexyl) phthalate correlates with decreased sperm DNA damage. Mono (2-ethyl-5-hydroxyhexyl) phthalate can be used in studies related to uterine leiomyoma .
loading...
    loading...
Cat. No.: HY-W014075
CAS No.: 5315-79-7
1-Hydroxypyrene, a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs), is analyzed in urine samples. 1-Hydroxypyrene is the major biomarker of exposure to pyrenes. 1-Hydroxypyrene is the orally active agonist for aryl hydrocarbon receptor (AhR) and can lead to renal fibrosis .
loading...
    loading...
Cat. No.: HY-113247
CAS No.: 3588-17-8
Purity:  99.93%
trans-trans-Muconic acid is a urinary metabolite of Benzene. trans-trans-Muconic acid serves as a urinary biomarker for occupational benzene exposure .
loading...
    loading...
Cat. No.: HY-W010255
CAS No.: 611-73-4
Synonyms: Benzoylformic acid
Phenylglyoxylic acid (Benzoylformic acid) is a metabolite of ethylbenzene and styrene (EB/S) and can be used as a biomarker of exposure to EB/S in human. Phenylglyoxylic acid can be used as drug intermediate for synthesis of antineoplastic compounds .
loading...
    loading...
Cat. No.: HY-113093S
CAS No.: 1135070-98-2
Purity:  ≥97.0%
Ethyl glucuronide-d5 is the deuterium labeled Ethyl glucuronide (HY-113093) . Ethyl glucuronide is an endogenous metabolite. Ethyl glucuronide is the metabolite of ethanol. Ethyl glucuronide is a biomarker for ethanol exposure that accumulates in hair and reflects the alcohol intake over a time period. Ethyl glucuronide is the agonist for TLR4 .
loading...
    loading...
Cat. No.: HY-W014075S
CAS No.: 132603-37-3
1-Hydroxypyrene-d9 is the deuterium labeled 1-Hydroxypyrene (HY-W014075). 1-Hydroxypyrene, a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs), is analyzed in urine samples. 1-Hydroxypyrene is the major biomarker of exposure to pyrenes. 1-Hydroxypyrene is the orally active agonist for aryl hydrocarbon receptor (AhR) and can lead to renal fibrosis .
loading...
    loading...
Cat. No.: HY-Y1097
CAS No.: 4376-18-5
Synonyms: 2-(Methoxycarbonyl)benzoic acid
Monomethyl phthalate is an orally active metabolite of phthalic acid. Monomethyl phthalate, as a urine biomarker after exposure to phthalate, can be used as a detection indicator for thyroid cancer and benign nodules. Monomethyl phthalate reduces the survival rate of young frogs. Monomethyl phthalate induces oxidative damage to red blood cells in rats .
loading...
    loading...
Cat. No.: HY-113239
CAS No.: 34834-67-8
Purity:  99.00%
Hydroxycotinine is a nicotine metabolite commonly found in the urine of smokers. Hydroxycotinine is the primary biomarker of tobacco/nicotine vapor exposure, formed from the conversion of nicotine via cotinine. Hydroxycotinine serum levels in rodents are influenced by sex and co-exposure to nicotine vapor and ethanol. Hydroxycotinine elevation is associated with decreased eGFR and increased risk of chronic kidney disease. Hydroxycotinine can be used in research related to chronic kidney disease .
loading...
    loading...
Cat. No.: HY-Y1097S
CAS No.: 1276197-40-0
Synonyms: 2-(Methoxycarbonyl)benzoic acid-d4
Monomethyl phthalate-d4 (2-(Methoxycarbonyl)benzoic acid-d4) is the deuterium labeled Monomethyl phthalate. Monomethyl phthalate is a phthalate metabolite. Monomethyl phthalate acts as a urinary biomarker of phthalates exposure and can be used as a standard for the determination of thyroid cancer and benign nodule .
loading...
    loading...
Cat. No.: HY-W008030
CAS No.: 2243-47-2
Target:  

Bacterial

Research Areas:  

Infection

3-Aminobiphenyl is a chemical isomer of 4-ABP. 3-Aminobiphenyl can inhibit the growth of human intestinal bacteria Bifidobacterium infantis ATCC 15697, B. bifidium ATCC 11863, Clostridium perfringens ATCC 13124, Escherichia coli ATCC 25922, E. coli ATCC 35218, Enterobacter cloacae ATCC 13047 and Salmonella typhimurium TA98, TA100, YG1041. 3-Aminobiphenyl can be used as a biomarker of exposure to aromatic amines from cigarette smoke .
loading...
    loading...
Cat. No.: HY-W341499
CAS No.: 4494-26-2
Target:  

Endogenous Metabolite

Research Areas:  

Others

5-Formyl-2'-deoxyuridine is a product formed when the 5-methyl group of thymine in DNA undergoes oxidation due to exposure to gamma radiation or certain chemical agents. Serving as a biomarker of oxidative DNA damage, 5-formyl-2'-deoxyuridine is employed in investigations of DNA damage and repair mechanisms. Additionally, 5-Formyl-2'-deoxyuridine can be used in studies involving chemically crosslinking with peptides derived from the RecA protein .
loading...
    loading...
Cat. No.: HY-116787
CAS No.: 948-71-0
Synonyms: 5-OHTBZ
Target:  

Drug Metabolite

Research Areas:  

Others

5-Hydroxythiabendazole (5-OHTBZ) is a biomarker of Thiabendazole (HY-B0263) exposure .
loading...
    loading...
Cat. No.: HY-N11222
CAS No.: 151109-67-0
Synonyms: C9 carnitine
Nonanoylcarnitine is a metabolite associated with chronic environmental exposure to polycyclic aromatic hydrocarbons (PAH) and fragmented QRS waves in acute myocardial infarction. Nonanoylcarnitine can be used as a potential biomarker for the metabolic outcome of PAH exposure and the prognosis of acute myocardial infarction .
loading...
    loading...
Cat. No.: HY-116496
CAS No.: 935-69-3
Purity:  98.13%
Synonyms: N7-Methyladenine
Research Areas:  

Cancer

7-Methyladenine (N7-Methyladenine), a methylated analog of Adenine (HY-B0152), is a biomarker of DNA damage from exposure to methylating agents .
loading...
    loading...
Cat. No.: HY-143368S
CAS No.: 1331906-27-4
L-Phenylmercapturic acid-d5 is the deuterium labeled L-Phenylmercapturic acid (HY-143368) . L-Phenylmercapturic acid is often used as a biomarker for exposure to aniline compounds such as aniline and xylene .
loading...
    loading...
Cat. No.: HY-113247S
CAS No.: 1955496-83-9
Purity:  99.80%
trans-trans-Muconic acid-d4 is the deuterium labeled trans-trans-Muconic acid . trans-trans-Muconic acid is a urinary metabolite of benzene and has been used as a biomarker of exposure to benzene in human .
loading...
    loading...