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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2851 Results for "
impurity.
" in MedChemExpress (MCE) Product Catalog:
Products (2851)
2851 Results for "impurity." in MCE Product Catalog:
3
3 Cited Publications
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Remdesivir O-desphosphate acetonide impurity is an impurity of Remdesivir. Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity and is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro .
2
2 Cited Publications
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Valsartan Ethyl Ester is an impurity of Valsartan. Valsartan is an angiotensin II receptor antagonist for the treatment of high blood pressure and heart failure .
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Omeprazole sulfone (Omeprazole sulphone) is one of the major circulating metabolites of Omeprazole (HY-B0113) in vivo, and belongs to class 4 non-mutagenic impurities. Omeprazole sulfone does not bind to the aryl hydrocarbon receptor (AhR), nor does it induce the expression of CYP1A1 or CYP1A2. However, Omeprazole sulfone promotes the migration of gastric epithelial cells under basal conditions and reverses the inhibitory effect of Indomethacin (HY-14397) on cell migration. Omeprazole sulfone does not promote cell proliferation, nor does it upregulate COX-2 expression or activate signaling pathways such as ERK, P38 MAPK and PI3K. Omeprazole sulfone maintains basal ulcer healing under non-acid-dependent conditions and can be used in studies related to gastric ulcer repair .
1
1 Cited Publications
Synonyms: Impurity A of Calcipotriol
MC 1046 (Impurity A of Calcipotriol) is a hepatic metabolite and an impurity of Calcipotriol (HY-10001). MC 1046 induces differentiation of histiocytic lymphoma cells. MC 1046 can be used for the research of histiocytic lymphoma .
1
1 Cited Publications
Cat. No.: HY-100067
CAS No.: 1076199-40-0
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Quetiapine impurity 1 is an impurity of Quetiapine (HY-14544).
1
1 Cited Publications
Synonyms: Tenivastatin sodium; Simvastatin Impurity A sodium
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Simvastatin hydroxy acid (Tenivastatin) sodium is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin hydroxy acid sodium reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin hydroxy acid sodium can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene .
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1,1,3-Tribromoacetone is an impurity of Methotrexate (HY-14519) . Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis .
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1
1 Cited Publications
Cat. No.: HY-W010712
CAS No.: 109425-51-6
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Cat. No.: HY-15266
CAS No.: 112827-99-3
Synonyms: PRI 2202; Impurity D of Calcipotriol
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24R-Calcipotriol (PRI 2202; Impurity D of Calcipotriol), an isomer of Calcipotriol (HY-10001), is a synthetic vitamin D analog. 24R-Calcipotriol exhibits synergistic antiproliferative effects with low-dose cytostatics in in vitro. 24R-Calcipotriol produces tumor growth inhibition when combined with Cyclophosphamide (HY-17420) and Cisplatin (HY-17394) in mice models. 24R-Calcipotriol can increase serum calcium levels and reduce blood leukocyte counts . 24R-Calcipotriol can be used for the research of mammary cancer and Lewis lung cancer .
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Impurity of Alfacalcidol. Alfacalcidol (1-hydroxycholecalciferol; Alpha D3; 1.alpha.-Hydroxyvitamin D3) is a non-selective VDR activator medication.
Synonyms: 1β,25-Dihydroxyvitamin-D3; 1-Epicalcitriol
Impurity B of Calcitriol is a diastereomer of 1α,25-dihydroxyvitamin D3 that interferes with accurate Calcitriol quantification .
Impurity F of Calcipotriol is a Vitamin D analog and an impurity of Calcipotriene (HY-10001) .
Cat. No.: HY-76937
CAS No.: 127516-23-8
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Impurity of Doxercalciferol is an impurity of doxercalciferol, which is a synthetic analog of ergocalciferol (vitamin D2), used as a agent for secondary hyperparathyroidism and metabolic bone disease, and it suppresses parathyroid synthesis and secretion.
Cat. No.: HY-13292R
CAS No.: 66791-71-7
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Impurity B of Calcitriol (Standard) is the analytical standard of Impurity B of Calcitriol. This product is intended for research and analytical applications.
Impurity C of Calcitriol is the impurity of Calcitriol (HY-10002). Calcitriol is the hormonally active form of vitamin D. Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).
Cat. No.: HY-Z6635
CAS No.: 496024-43-2
Synonyms: Amlodipine impurity 31
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Amlodipine impurity 8 (Amlodipine impurity 31) is an impurity of Amlodipine.
Cat. No.: HY-137359
CAS No.: 34378-65-9
Synonyms: Methotrexate impurity 10
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Methotrexate impurity 6 (Methotrexate impurity 10) is an impurity of Methotrexate.
Cat. No.: HY-Z6691
CAS No.: 203395-78-2
Synonyms: Aripiprazole Impurity 19
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Aripiprazole impurity 17 (Aripiprazole Impurity 19) is an impurity of Aripiprazole.
Cat. No.: HY-Z9066
CAS No.: 150899-33-5
Synonyms: Methylprednisolone impurity 21
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Methylprednisolone acetate impurity 4 (Methylprednisolone impurity 21) is an impurity of Methylprednisolone acetate.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
