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Results for "

kinetics

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (2) ADC Linker (2) Amylases (1) Amyloid-β (2) Angiotensin Receptor (1) Apoptosis (2) Arf Family GTPase (1) ATP Synthase (1) Autophagy (2) Bacterial (4) Biochemical Assay Reagents (18) Calcium Channel (3) COX (2) Cytochrome P450 (3) Dopamine Receptor (2) Drug Intermediate (4) Drug Metabolite (8) DYRK (1) EGFR (1) Endogenous Metabolite (47) Endothelin Receptor (1) Environmental Pollutants (4) Epigenetic Reader Domain (1) ERK (1) FAP (3) Fluorescent Dye (14) Fungal (1) Glutathione Peroxidase (1) Glycosidase (5) GSK-3 (1) HDAC (1) Hepcidin (2) Herbicide (1) Histamine Receptor (1) Histone Methyltransferase (2) HSP (2) iGluR (2) IMPDH (1) mAChR (1) MALT1 (1) Microtubule/Tubulin (1) Mitochondrial Metabolism (1) mTOR (1) NAMPT (1) Opioid Receptor (3) p38 MAPK (1) Parasite (2) Phosphatase (4) Phosphodiesterase (PDE) (3) Photosensitizer (1) Potassium Channel (5) PROTACs (1) Reactive Oxygen Species (ROS) (1) Reference Standards (7) Sodium Channel (7) Thyroid Hormone Receptor (1) Toll-like Receptor (TLR) (1) UGT (1)
By Research Areas:	Cancer (24) Cardiovascular Disease (10) Endocrinology (1) Infection (9) Inflammation/Immunology (14) Metabolic Disease (8) Neurological Disease (23)
Click Chemistry:	Labeling and Fluorescence Imaging (1) DBCO (3) Azide (1) Alkynes (1)
Oligonucleotides:	Nucleotide Analogs (1)

150

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-128643

FAPI-4 30+ Cited Publications	FAP	Cancer
FAPI-4 is a potent fibroblast activation protein (FAP) inhibitor for the targeting FAP. FAPI-4 can be used in cancer research. ⁶⁸Ga-FAPI-4 PET/CT is a promising new diagnostic method for imaging various kinds of cancer, with good tumor-to-background contrast ratios .

HY-W015239

KAT8-IN-1 3 Publications Verification	Acyltransferase	Inflammation/Immunology Cancer
KAT8-IN-1 is a lysine (K) acetyltransferase 8 (KAT8) inhibitor, with IC₅₀s of 141 μM (KAT8), 221 μM (KAT2B), 106 μM (KAT3B), respectively. KAT8 inhibits histone acetyltransferases (HATs), and could result in disease states, such as cancer or inflammatory diseases .

HY-N1495

Maltopentaose Maltopentose	Amylases	Others
Maltopentaose is the shortest chain oligosaccharide. Maltopentaose is a substrate for α-amylases. Maltopentaose can be classified as maltodextrin and is also used in a study to investigate glycation and phosphorylation of α-lactalbumin. Maltopentaose is used to study the inhibition kinetics of human pancreatic α-amylase by dehydrodieugenol B .

HY-137822

p-Nitrophenyl α-D-mannopyranoside 4-Nitrophenyl a-D-mannopyranoside	Glycosidase	Others
p-Nitrophenyl α-D-mannopyranoside (4-Nitrophenyl α-D-mannopyranoside) is a chromogenic glycosidic ligand. p-Nitrophenyl α-D-mannopyranoside features a sugar moiety (α-D-mannopyranose) with the mannose-characteristic axial hydroxyl group at the C2 position and a ligand portion (p-nitrophenol) that provides ultraviolet-visible light absorption properties. p-Nitrophenyl α-D-mannopyranoside can be used to determine glycosidase activity and characterize the sugar recognition properties of lectins (such as Concanavalin A (HY-P2149)) .

HY-E70336

Peroxidase, Lignin	Endogenous Metabolite	Others
Peroxidase, Lignin is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .

HY-100034

NSC 663284 5+ Cited Publications DA-3003-1	Phosphatase Histone Methyltransferase	Cancer
NSC 663284 (DA-3003-1) is a potent, cell-permeable, and irreversible Cdc25 dual specificity phosphatase inhibitor, has an IC₅₀ for Cdc25B2 of 0.21 μM. NSC 663284 exhibits mixed competitive kinetics against Cdc25A, Cdc25B(2), and Cdc25C with Ki values of 29, 95, and 89 nM, respectively . NSC 663284 inhibits NSD2 (IC₅₀ of 170 nM) through a direct interaction with the catalytic SET domain (K_d of 370 nM) .

HY-122376

S-Bioallethrin D-Trans-Allethrin; Esbiol	Environmental Pollutants Sodium Channel	Neurological Disease
S-Bioallethrin (D-Trans-Allethrin) is a pyrethroid insecticide. S-Bioallethrin disrupts nerve function by modifying the gating kinetics of transitions between the conducting and nonconducting states of voltage-gated sodium channels. S-Bioallethrin also causes inhibition of lymphocyte proliferation and induces histamine release from human basophils .

HY-137333

4-Methylumbelliferyl β-D-cellobioside	Fluorescent Dye	Others
4-Methylumbelliferyl β-D-cellobioside is a substrate of Cellulase (HY-B2220). 4-Methylumbelliferyl β-D-cellobioside can be hydrolyzed and produces fluorescent 4-methylumbelliferone, which can be used to study the kinetics of cellulases .

HY-W008129

H-D-cis-Hyp-OH	Endogenous Metabolite	Infection
H-D-cis-Hyp-OH (cis-4-Hydroxy-D-proline) is a proline derivative involved in bacterial metabolic pathways and is a substrate for cis-4-hydroxy-D-proline dehydrogenase. H-D-cis-Hyp-OH is a precursor for the synthesis of conformationally constrained PNA adenine monomers and can be used to study the specificity and kinetics of D-alanine dehydrogenase .

HY-B0445B

α-NAD α-Nicotinamide Adenine Dinucleotide	Mitochondrial Metabolism Endogenous Metabolite	Metabolic Disease
α-NAD (α-Nicotinamide Adenine Dinucleotide) serves as a substrate for reninase, functions as an analog of β-NAD, affects the kinetics of NAD-dependent enzymes, and also plays a critical role as a cofactor in mitochondrial redox reactions .

HY-151720

Cy5.5 DBCO 1 Publications Verification	ADC Linker	Others
Cy5.5 DBCO is a click chemistry reagent containing an cycloalkynes group. Cy5.5 DBCO is a linker of Cyanine5.5 fluorophore. DBCO group enables copper free biocompatible click chemistry with fast reaction kinetics and good stability .

HY-E70333

Microgranulated pectolytic enzyme AR2000	Endogenous Metabolite	Others
Microgranulated pectolytic enzyme is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .

HY-E70332

Lipase, Aspergillus niger	Endogenous Metabolite	Others
Lipase, Aspergillus niger is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .

HY-15404

Darusentan Lu-135252	Endothelin Receptor	Cardiovascular Disease Endocrinology
Darusentan (Lu-135252) is a selective endothelin receptor A (ET-A) receptor antagonist, which binds with a K_i of 1.4 nM to the ET-A receptor and a K_i of 184 nM to ET-B receptor, respectively with a 100-fold selectivity for ETA rather than ETB receptors . Darusentan competes for radiolabeled endothelin binding in rat aortic vascular smooth muscle cells (RAVSMs) membranes with single-site kinetics, exhibiting a K_i of 13 nM .

HY-131682

3-C6-NBD-cholesterol 3-Hexanoyl-NBD-cholesterol	Fluorescent Dye	Others
3-C6-NBD-cholesterol is a fluorescent analog of Chol that can be used to measure the kinetics of membrane and intracellular trafficking .

HY-E70335

Colipase, Porcine	Endogenous Metabolite	Others
Colipase, Porcine is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .

HY-E70353

Trypsin-Chymotrypsin 6:1	Endogenous Metabolite	Others
Trypsin-Chymotrypsin 6:1 is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .

HY-E70312

High-efficiency lipase,Candida antarctica (Immobilized on hydrophilic carrier)	Endogenous Metabolite	Others
High-efficiency lipase,Candida antarctica (Immobilized on hydrophilic carrier) is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .

HY-117822

BRD0209	GSK-3	Neurological Disease Metabolic Disease Cancer
BRD0209 is a potent, selective and dual inhibitor of GSK3α/β inhibitor (GSK3α IC₅₀ = 19 nM; GSK3β IC₅₀ = 5 nM). BRD0209 is also a reversible ATP-competitive inhibitor with fast-off kinetics (K_i = 4.2 nM, respectively). BRD0209 is a tricyclic pyrazolotetrahydroquinolinone compound. BRD0209 has the potential for the research of mood disorder diseases .

HY-W003371

CGP 44 645	Drug Metabolite	Others
CGP 44 645 is the methanol metabolite of Letrozole (HY-14248) and is a molecular indicator for evaluating its metabolic kinetics in microsomes in vitro. Levels of CGP 44 645 in rat liver microsomes may be sex-specific .

HY-P2876

Tryptophanase	Bacterial	Others
Tryptophanase is a zymogen-converting enzyme and inducible enzyme that can convert its inactive precursor form into an active enzyme without additional polypeptide synthesis. In Escherichia coli K12, tryptophanase functions as an inducible enzyme, and its induction kinetics are similar to those of β-galactosidase. Tryptophanase catalyzes the conversion of L-tryptophan to indole .

HY-21170E

Zinc trifluoromethanesulfonate Zinc(II) Triflate	Biochemical Assay Reagents	Others
Zinc trifluoromethanesulfonate (Zinc (II) Triflate) is a Zn ²⁺ salt commonly used in potentiometric titration to determine the stability constants of Zn ²⁺-quinoline sulfonamide complexes. Aqueous solutions of Zinc trifluoromethanesulfonate form micellar structures, which result in poor desolvation kinetics of Zn ²⁺ and induce dendrite growth on zinc anodes, failing to support long-term cycling of zinc anodes .

HY-174210

PROTAC BRD4 Degrader-31	PROTACs Epigenetic Reader Domain	Cancer
PROTAC BRD4 Degrader-31 is a BRD4 PROTAC degrader with DC₅₀ s of 164 and 80 nM at 4 h and 24 h, respectively. PROTAC BRD4 Degrader-31 potently degrades BRD4 in cells with long acting degradation kinetics . Pink: BRD4 ligand (HY-78695); Blue: KLHDC2 ligand (HY-174218)

HY-117374

HDAC3-IN-1 1 Publications Verification	HDAC	Cancer
HDAC3-IN-1 (compound 5) is a potent and selective HDAC3 inhibitor, with an IC₅₀ of 5.96 nM .

HY-W099571

Lithium stearate 20+ Cited Publications Stearic acid lithium; Lithium octadecanoate	Environmental Pollutants Biochemical Assay Reagents	Others
Lithium stearate (Stearic acid (lithium)) is a compound that forms vesicles in reaction with silver nitrate, thereby changing the reaction kinetics of the nucleation and self-assembly process of silver stearate. It has the activity that even in the presence of excess silver nitrate, only about 80% can be converted into silver stearate and the residual lithium stearate will inhibit the growth process of silver stearate crystals, thereby producing silver stearate crystals that are much smaller than those obtained from sodium stearate, providing an opportunity to further control the self-assembly and crystal growth of silver stearate.

HY-P2881

Nucleoside diphosphate kinase Nucleoside 5′-diphosphate kinase	Biochemical Assay Reagents	Cancer
Nucleoside diphosphate kinase (Nucleoside 5′-diphosphate kinase) belongs to the family of structurally and functionally conserved NDPK (Nucleotide diphosphate kinase) enzymes. Nucleoside diphosphate kinase catalyzes the reversible transfer of γ-phosphates between nucleoside di-(NDP) and triphosphates (NTP) through ping-pong bi-bi reaction kinetics. Nucleoside diphosphate kinase is the essential housekeeping proteins that produces CTP (cytidine triphosphate) for lipid syntheses, UTP (Uridine triphosphate) for polysaccharide syntheses, and GTP (guanosine triphosphate) for protein syntheses, signal transduction, and microtubules polymerization .

HY-W012232

2,6-Diphenylpyridine	Biochemical Assay Reagents Drug Intermediate	Others
2,6-Diphenylpyridine is a proton acceptor (log(P) = 5) and a tridentate [C^N^C] dianionic ligand. 2,6-Diphenylpyridine efficiently transfers protons through a direct pathway at the interface of two immiscible electrolyte solutions. 2,6-Diphenylpyridine as a tridentate ligand and can form mononuclear and binuclear complexes with gold(III). 2,6-Diphenylpyridin is applicable to research in electrochemical ion transfer kinetics and organometallic chemistry .

HY-158615

STING18 Stimulator of interferon genes 18	Others	Others
STING18 (Stimulator of interferon genes 18) is a compound that inhibits STING protein by utilizing a small molecule active site dimer, with good oral exposure, slow binding kinetics, and functional inhibitory activity on STING-mediated cytokine release.

HY-E70337

Heparanase 1, Human	Endogenous Metabolite	Others
Heparanase 1, Human is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .

HY-128642

FAPI-2	FAP	Cancer
FAPI-2 is a quinoline-based fibroblast activation protein (FAP)-targeting ligand that can be labeled as ⁶⁸Ga-FAPI-2 and used as a PET tracer for cancer diagnosis. FAPI-2 has advantages such as fast tracer kinetics, no need for fasting preparation, and being unaffected by blood glucose .

HY-158800

1-NBD-decanoyl-2-decanoyl-sn-glycerol	Biochemical Assay Reagents	Others
1-NBD-decanoyl-2-decanoyl-sn-glycerol is a diacylglycerol (DAG) derivative, which is labeled with a fluorescent group NBD. 1-NBD-decanoyl-2-decanoyl-sn-glycerol is the substrate for diacylglycerol kinase (DGK), and can be used for quantitative detection of the DGF enzyme kinetics in vitro, and the changes in DAG and PA during cell signaling .

HY-P1218

Phrixotoxin 3	Sodium Channel	Neurological Disease
Phrixotoxin 3 is a potent blocker of voltage-gated sodium channels, with IC₅₀s of 0.6, 42, 72, 288, 610 nM for NaV1.2, NaV1.3, NaV1.4, NaV1.1 and NaV1.5, respectively. Phrixotoxin 3 modulates voltage-gated sodium channels with properties similar to those of typical gating-modifier toxins, both by causing a depolarizing shift in gating kinetics and by blocking the inward component of the sodium current .

HY-A0229

Saprisartan GR 138950	Angiotensin Receptor	Others
Saprisartan (GR 138950) is a selective, long-acting AT1 receptor antagonist with low receptor dissociation kinetics.

HY-161345

Meriolin 16	Apoptosis	Cancer
Meriolin 16 can induce cell apoptosis in rapid kinetics (within 2-3 h) with the IC₅₀ of 50 nM .

HY-138126A

Dansyl-Tyr-Val-Gly TFA	Others	Others
Dansyl-Tyr-Val-Gly TFA is a substrate of peptidylglycine monooxygenase (PHM), with a K_D of 22 μM for PHM. Dansyl-Tyr-Val-Gly TFA can be used to investigate the catalytic mechanism, kinetics and inactivation characteristics of PHM .

HY-E70331

Acid Stable Protease	Endogenous Metabolite	Others
Acid Stable Protease is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .

HY-E70354

Protease for flavors	Endogenous Metabolite	Others
Protease for flavors is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .

HY-E70347

Tn5 Transposase	Endogenous Metabolite	Others
Tn5 Transposase is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .

HY-D0234

o-Cresolphthalein ortho-Cresolphthalein	Endogenous Metabolite	Others
o-Cresolphthalein (ortho-Cresolphthalein) is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .

HY-E70352

Trypsin-Chymotrypsin 1:250	Endogenous Metabolite	Others
Trypsin-Chymotrypsin 1:250 is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .

HY-N16302

Cyanine 5.5 DBCO chloride	Fluorescent Dye	Others
Cyanine 5.5 DBCO chloride is a click chemistry reagent containing an cycloalkynes group. Cyanine 5.5 DBCO chloride is a linker of Cyanine5.5 fluorophore. DBCO group enables copper free biocompatible click chemistry with fast reaction kinetics and good stability (Ex/Em = 680/715 nm) .

HY-D2253

Direct Blue 108	Fluorescent Dye	Others
Direct Blue 108 has the structure of triphenyl two oxazine, and can be used in dyeing of cotton, viscose fiber, silk and its blended fabrics .

HY-128642A

FAPI-2 TFA	FAP	Cancer
FAPI-2 TFA is a quinoline-based fibroblast activation protein (FAP)-targeting ligand that can be labeled as ⁶⁸Ga-FAPI-2 and used as a PET tracer for cancer diagnosis. FAPI-2 TFA has advantages such as fast tracer kinetics, no need for fasting preparation, and being unaffected by blood glucose .

HY-120791

Lysyllysine L-Lysyl-L-lysine	Drug Intermediate	Others
Lysyllysine (L-Lysyl-L-lysine) is a dipeptide composed of two L-lysine amino acids linked together. Lysyllysine is often used as an enzyme cleavage linker for connecting bioactive peptides, or as a component of more complex antibacterial agents .

HY-W140208

3-Phenylthiophene	Cytochrome P450	Neurological Disease
3-Phenylthiophene (Compound 25) is a CYP2A6 inhibitor with a K_i value of 3.3 μM. The K_i values for CYP2E1, CYP2B6, CYP2C9, and CYP2C19 are 9.7, 14, 112, and 107 μM respectively. It shows no significant inhibition on CYP3A4 and CYP2D6. 3-Phenylthiophene can be used in smoking cessation research .

HY-170789

H1R ligand-1	Histamine Receptor	Neurological Disease
H1R ligand-1 (Compound fragment 1) is a high-affinity ligand for the human histamine H1 receptor (H1R). H1R ligand-1 can be used as a scaffold to design and synthesize a set of derivatives to explore H1R binding kinetics .

HY-W800838

BP Fluor 488 Tetrazine	Fluorescent Dye	Cancer
BP Fluor 488 Tetrazine is a bright, green-fluorescent probe used for detection TCO-tagged biopolymers. BP Fluor 488 Tetrazine demonstrates exceptionally fast cycloaddition kinetics (up to 30 000 M-1 s-1) with trans-cyclooctenes (TCO) as the dienophile, the fastest kinetics ever reported for any bioorthogonal reaction. In applications such as in vivo cancer imaging or pre?targeted cell labeling studies where rapid reaction kinetics is a must BP Fluor 488 Tetrazine probe would of great value.

HY-D0910

5-Bromo-6-chloro-1H-indol-3-yl acetate	Biochemical Assay Reagents	Others
5-Bromo-6-chloro-1H-indol-3-yl acetate, a member of the indole family, is a derivative of the aromatic heterocyclic compound indole. It has been used in a variety of research settings, including studies of enzyme kinetics and protein-ligand interactions. 5-Bromo-6-chloro-1H-indol-3-yl acetate is a biomaterial or organic compound that can be used as a biomaterial or organic compound related to life science research .

HY-134425

β-Methylcrotonyl coenzyme A lithium	Endogenous Metabolite	Metabolic Disease
β-Methylcrotonyl coenzyme A lithium is an intermediate in leucine metabolism and can be used as a substrate to study the specificity and kinetics of β-methylcrotonyl coenzyme A carboxylase (MCCase) .

HY-107697

N20C hydrochloride	iGluR	Neurological Disease
N20C hydrochloride is a selective and noncompetitive open NMDA receptor open channel blocker, with micromolar affinity, fast on-off blockade kinetics, and strong voltage dependence. Neuroprotective activity .

Cat. No.	Product Name

HY-L214

Liposome Library

192 compounds

Liposomes are spherical or multilayered spherical vesicles formed by the self-assembly of diacyl chain phospholipids (lipid bilayers) in aqueous solutions, which can be made from natural or synthetic phospholipids and exhibit good biocompatibility and low toxicity. They can serve as delivery carriers for various bioactive substances (such as drugs, proteins, nucleic acids, etc.) and are widely used in biomedical and chemical research. The main advantages of liposomes include 1) Protective effect: Their bilayer structure can protect encapsulated molecules from enzymatic degradation, oxidation, and other influences, extending stability and activity; 2) Active targeting: Surface modifications enable active targeting, enhancing the concentration of drugs or molecules in specific tissues or cells; 3) Customizability: The composition and structure of liposomes can be adjusted according to needs, such as altering phospholipid types or adding targeting ligands. These properties make liposomes highly valuable in developing novel drug delivery systems, serving as nucleic acid carriers for gene transfection, studying cellular uptake mechanisms and drug release kinetics, as well as developing functional food additives to improve the bioavailability of nutritional components.

MCE contains 192 liposome compounds, which is a good tool for lipidomic-related studies.

Cat. No.	Product Name	Type

HY-D1069

DBCO-Cy3

1 Publications Verification

DBCO-Sulfo-Cy3

Fluorescent Dye

DBCO-Cy3 (DBCO-Sulfo-Cy3) is the derivative of Cyanine3 fluorophore, a pH insensitive from pH (4-10) orange fluorescent dyewith excitation maximum 555 nm and emission maximum of 580nm. DBCO-Cy3 has fast reaction kinetics and good stability, and is productive to use in many standard fluorescent instrumentations. DBCO-Cy3 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-D2253

Direct Blue 108	Fluorescent Dye
Direct Blue 108 has the structure of triphenyl two oxazine, and can be used in dyeing of cotton, viscose fiber, silk and its blended fabrics .

HY-D2931

SNAP-FAM	Fluorescent Dye
SNAP-FAM is a FAM-labeled SNAP tag fluorescent probe, specifically designed for live-cell protein labeling and real-time imaging applications .

HY-W800838

BP Fluor 488 Tetrazine

Fluorescent Dye

BP Fluor 488 Tetrazine is a bright, green-fluorescent probe used for detection TCO-tagged biopolymers. BP Fluor 488 Tetrazine demonstrates exceptionally fast cycloaddition kinetics (up to 30 000 M-1 s-1) with trans-cyclooctenes (TCO) as the dienophile, the fastest kinetics ever reported for any bioorthogonal reaction. In applications such as in vivo cancer imaging or pre?targeted cell labeling studies where rapid reaction kinetics is a must BP Fluor 488 Tetrazine probe would of great value.

HY-D2200

Cy5.5(Me)-C3-DBCO	Fluorescent Dye
Cy5.5(Me)-C3-DBCO is a click chemistry reagent containing an cycloalkynes group. DBCO group enables copper free biocompatible click chemistry with fast reaction kinetics and good stability .

HY-D2989

BG-NH2-Ac-N3 SNAP-NH2-Ac-N3	Fluorescent Dye
BG-NH2-Ac-N3 (SNAP-NH2-Ac-N3) is a nitrogen-containing SNAP tag with a nitro group. BG-NH2-Ac-N3 can be used for click chemistry labeling .

HY-D3394

SGC5

Fluorescent Dye

SGC5 is a fluorescence enhancer and membrane dissociator with millisecond-scale membrane dissociation kinetics, with an emission spectrum of 500-650 nm. SGC5 produces strong fluorescence upon binding to lipid membranes, exhibits fast partitioning dissociation kinetics at higher temperatures, and is unaffected by pH or cholesterol. SGC5 does not belong to the FM dye family and shows the highest membrane-bound fluorescence intensity among the tested styryl/FM dyes. SGC5 can be used to study synaptic vesicle cycling in neurons .

HY-125749

Coumarin-30	Fluorescent Dye
Coumarin-30 is a coumarin-based fluorescent dye and environment-sensitive fluorescent probe (in aqueous medium, λ_ex = 430 nm, λ_em = 495 nm). Coumarin-30 serves as a dopant for organic light-emitting diodes .

Cat. No.	Product Name	Type

HY-137822

p-Nitrophenyl α-D-mannopyranoside

4-Nitrophenyl a-D-mannopyranoside

Biochemical Assay Reagents

p-Nitrophenyl α-D-mannopyranoside (4-Nitrophenyl α-D-mannopyranoside) is a chromogenic glycosidic ligand. p-Nitrophenyl α-D-mannopyranoside features a sugar moiety (α-D-mannopyranose) with the mannose-characteristic axial hydroxyl group at the C2 position and a ligand portion (p-nitrophenol) that provides ultraviolet-visible light absorption properties. p-Nitrophenyl α-D-mannopyranoside can be used to determine glycosidase activity and characterize the sugar recognition properties of lectins (such as Concanavalin A (HY-P2149)) .

HY-W134328

Blue dextran (MW 2000000)

Dextran blue (MW 2000000)

Biochemical Assay Reagents

Blue dextran (Dextran blue) (MW 2000000) is a high-molecular-weight long-chain polymer of D-glucose. Blue dextran (MW 2000000) serves as an important model macromolecular drug and molecular weight estimation marker, and can be used as a standard for gel permeation chromatography. The release of Blue dextran (MW 2000000) from alginate microspheres is regulated by preparation conditions; its release rate in a pH 6.8 environment is significantly faster than that in pH 1.2, and it exhibits release characteristics close to zero-order kinetics under this condition .

HY-W011654

4-Aminophenyl-β-D-galactopyranoside, 98%

4-Aminophenyl-beta-D-galactopyranoside, 98%

Biochemical Assay Reagents

4-Aminophenyl-β-D-galactopyranoside, 98% is a highly efficient substrate for β-galactosidase. It is specifically hydrolyzed by this enzyme to release galactose and electroactive p-aminophenol. 4-Aminophenyl-β-D-galactopyranoside, 98% is widely used in colorimetric and electrochemical assays for detecting β-galactosidase activity and determining enzyme kinetics, such as in biosensing fields including cellular senescence, pathogen and contaminant detection. In addition, since β-galactosidase is often overexpressed in primary ovarian cancer, 4-Aminophenyl-β-D-galactopyranoside, 98% can also be applied to related research on primary ovarian cancer .

HY-W110929

Acid blue 1 Xylene blue; C.I. Acid blue 1	Biochemical Assay Reagents
Acid blue 1 (Xylene blue) is an anionic triarylmethane dye and substrate for photocatalytic degradation .

HY-75070

(+)-1-(1-Naphthyl)ethylamine

Biochemical Assay Reagents

(+)-1-(1-Naphthyl)ethylamine ((+)-1-(1-NEA)) is a chiral modifier used to introduce enantioselectivity in catalytic hydrogenation reactions. 1-NEA can undergo H-D exchange with D2 in solution to form N?D bonds. That is, 1-NEA can complete Pt surface adsorption and protonation through amine N atoms, indicating that NEA molecules have the potential to impart enantioselectivity to Pt hydrogenation catalysts .

HY-W250721C

Carbomer 941 CBM 941	Biochemical Assay Reagents
Carbomer 941 (CBM 941) is an acrylic acid polymer, which can be used as a thickening agent. Carbomer 941 provides a stable gel matrix, exhibits good heat, light and microbial contamination resistance. Carbomer 941 facilitates the drug release and local application, which can be used in the pharmaceutical industry .

HY-Y0425

Terephthalaldehyde

Biochemical Assay Reagents

Terephthalaldehyde is a crosslinking agent. Terephthalaldehyde forms a crosslinked structure inside the gelatin matrix by forming Schiff base imines with the amino groups of gelatin, thereby constructing a three-dimensional network. Terephthalaldehyde improves the hydrophobicity of the gelatin matrix, delays water vapor penetration and enhances the liquid water resistance of gelatin films. Terephthalaldehyde can be used as a crosslinking agent to prepare crosslinked chitosan hydrogel (CAAT) via ultrasound-induced synthesis. Terephthalaldehyde helps CAAT hydrogels selectively adsorb anionic dyes from aqueous media, including multi-component systems containing cationic dyes. Terephthalaldehyde serves as a starting material for the synthesis of bis-heterocyclic compounds (including bis-thiazole and bis-triazolopyrimidine compounds) .

HY-158220C

Hyaluronic acid methacryloyl (MW 50000)

HAMA (MW 50000)

Biochemical Assay Reagents

Hyaluronic acid methacryloyl (HAMA) (MW 50000) is a methacrylate-modified hyaluronic acid that serves as a hydrogel former, hydrolysis-resistant material, photocrosslinkable hydrogel scaffold, and drug delivery carrier for tissue engineering. Hyaluronic acid methacryloyl (MW 50000) forms hydrogels via photocrosslinking; when combined with AuMA NPs through a one-step photocrosslinking method, its effective swelling ratio increases, and the mechanical reinforcement effect of Au NPs compensates for the impact caused by reduced crosslinking density. Hyaluronic acid methacryloyl (MW 50000) can be combined with AuMA NPs via a one-step photocrosslinking method, enabling non-invasive monitoring of hydrogel degradation with contrast-enhanced micro-CT .

HY-D0234

o-Cresolphthalein ortho-Cresolphthalein	Biochemical Assay Reagents
o-Cresolphthalein (ortho-Cresolphthalein) is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .

HY-D0910

5-Bromo-6-chloro-1H-indol-3-yl acetate

Biochemical Assay Reagents

5-Bromo-6-chloro-1H-indol-3-yl acetate, a member of the indole family, is a derivative of the aromatic heterocyclic compound indole. It has been used in a variety of research settings, including studies of enzyme kinetics and protein-ligand interactions. 5-Bromo-6-chloro-1H-indol-3-yl acetate is a biomaterial or organic compound that can be used as a biomaterial or organic compound related to life science research .

HY-134425

β-Methylcrotonyl coenzyme A lithium	Biochemical Assay Reagents
β-Methylcrotonyl coenzyme A lithium is an intermediate in leucine metabolism and can be used as a substrate to study the specificity and kinetics of β-methylcrotonyl coenzyme A carboxylase (MCCase) .

Cat. No.	Product Name	Target	Research Area

HY-138126

Dansyl-Tyr-Val-Gly	Peptides	Others
Dansyl-Tyr-Val-Gly is a substrate of peptidylglycine monooxygenase (PHM), with a K_D of 22 μM for PHM. Dansyl-Tyr-Val-Gly can be used to investigate the catalytic mechanism, kinetics and inactivation characteristics of PHM .

HY-P1218B

Phrixotoxin 3-NH2 TFA	Sodium Channel	Neurological Disease
Phrixotoxin 3-NH2 TFA is a derivative of Phrixotoxin 3 TFA (HY-P1218A). Phrixotoxin 3 TFA is a potent blocker of voltage-gated sodium channels, with IC₅₀s of 0.6, 42, 72, 288, 610 nM for NaV1.2, NaV1.3, NaV1.4, NaV1.1 and NaV1.5, respectively. Phrixotoxin 3 TFA modulates voltage-gated sodium channels with properties similar to those of typical gating-modifier toxins, both by causing a depolarizing shift in gating kinetics and by blocking the inward component of the sodium current .

HY-P1218

Phrixotoxin 3	Sodium Channel	Neurological Disease
Phrixotoxin 3 is a potent blocker of voltage-gated sodium channels, with IC₅₀s of 0.6, 42, 72, 288, 610 nM for NaV1.2, NaV1.3, NaV1.4, NaV1.1 and NaV1.5, respectively. Phrixotoxin 3 modulates voltage-gated sodium channels with properties similar to those of typical gating-modifier toxins, both by causing a depolarizing shift in gating kinetics and by blocking the inward component of the sodium current .

HY-P5368

[Arg6]-β-Amyloid (1-40), england mutation	Peptides	Others
[Arg6]-β-Amyloid (1-40), england mutation is a biological active peptide. (Several mutations in the beta amyloid precursor gene cause autosomal dominant Alzheimer's Disease in a number of kindreds. Among them, the English mutation, with His at position 6 replaced with Arg, was reported to accelerate the kinetics of oligomers formation which act as fibril seeds and are more toxic to cultured neuronal cells.)

HY-P1218A

Phrixotoxin 3 TFA	Sodium Channel	Neurological Disease
Phrixotoxin 3 TFA is a potent blocker of voltage-gated sodium channels, with IC₅₀s of 0.6, 42, 72, 288, 610 nM for NaV1.2, NaV1.3, NaV1.4, NaV1.1 and NaV1.5, respectively. Phrixotoxin 3 TFA modulates voltage-gated sodium channels with properties similar to those of typical gating-modifier toxins, both by causing a depolarizing shift in gating kinetics and by blocking the inward component of the sodium current .

HY-P3118

Bz-IEGR-pNA acetate	Biochemical Assay Reagents	Others
Bz-IEGR-pNA acetate is a trypsin substrate that can be hydrolyzed by prostate kinase release enzyme-related peptide KLKs .

HY-P11427

Ac-LVSR-AMC	Fluorescent Dye MALT1	Inflammation/Immunology Cancer
Ac-LVSR-AMC is a tetrapeptide fluorescent substrate that can be used for in vitro quantitative detection of the specific activity of the Malt1 protease .

Species:	Rat (2)
Tag:	His (1) Fc (1)
Source:	HEK293 (2)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P77379

	HEPACAM2 Protein, Rat (HEK293, His) HEPACAM family member 2; Mitotic kinetics regulator; MIKI	Rat	HEK293
	The HEPACAM2 gene encodes a protein associated with an immunoglobulin superfamily that plays a role in mitosis. Knocking down this gene can lead to prophase cell arrest, abnormal nuclear morphology and apoptosis. HEPACAM2 can be used as a biomarker for the prognosis of colorectal adenocarcinoma. HEPACAM2 Protein, Rat (HEK293, His) is the recombinant rat-derived HEPACAM2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P77378

	HEPACAM2 Protein, Rat (HEK293, Fc) HEPACAM family member 2; Mitotic kinetics regulator; MIKI	Rat	HEK293
	The HEPACAM2 gene encodes a protein associated with an immunoglobulin superfamily that plays a role in mitosis. Knocking down this gene can lead to prophase cell arrest, abnormal nuclear morphology and apoptosis. HEPACAM2 can be used as a biomarker for the prognosis of colorectal adenocarcinoma. HEPACAM2 Protein, Rat (HEK293, Fc) is the recombinant rat-derived HEPACAM2 protein, expressed by HEK293 , with C-hFc labeled tag.

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HY-D1069

DBCO-Cy3 1 Publications Verification DBCO-Sulfo-Cy3		DBCO Labeling and Fluorescence Imaging
DBCO-Cy3 (DBCO-Sulfo-Cy3) is the derivative of Cyanine3 fluorophore, a pH insensitive from pH (4-10) orange fluorescent dyewith excitation maximum 555 nm and emission maximum of 580nm. DBCO-Cy3 has fast reaction kinetics and good stability, and is productive to use in many standard fluorescent instrumentations. DBCO-Cy3 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-151720

Cy5.5 DBCO 1 Publications Verification		DBCO
Cy5.5 DBCO is a click chemistry reagent containing an cycloalkynes group. Cy5.5 DBCO is a linker of Cyanine5.5 fluorophore. DBCO group enables copper free biocompatible click chemistry with fast reaction kinetics and good stability .

HY-D2200

Cy5.5(Me)-C3-DBCO		DBCO
Cy5.5(Me)-C3-DBCO is a click chemistry reagent containing an cycloalkynes group. DBCO group enables copper free biocompatible click chemistry with fast reaction kinetics and good stability .

HY-D2989

BG-NH2-Ac-N3 SNAP-NH2-Ac-N3		Azide
BG-NH2-Ac-N3 (SNAP-NH2-Ac-N3) is a nitrogen-containing SNAP tag with a nitro group. BG-NH2-Ac-N3 can be used for click chemistry labeling .

HY-181085

RD0448		Alkynes
RD0448 is a potent inhibitor of DYRK1A, DYRK1B, and DYRK2. RD0448 selectively targets the non-native (folded intermediate) state of DYRK1A and DYRK1B. The binding site of RD0448 is hidden in the native state of DYRK1A and DYRK1B, and as a stabilizing binder, it binds tightly to both DYRK1A and DYRK1B, forming a stable complex with slow dissociation kinetics. In contrast, RD0448 targets the native state of DYRK2 without selectivity between its native and non-native states, acting as a weak binder with weaker binding affinity to DYRK2 and forming a rapidly dissociating complex .

Cat. No.	Product Name		Classification

HY-113066A

Guanosine 5'-diphosphate disodium salt 2 Publications Verification GDP disodium salt		Nucleotide Analogs
Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K ⁺ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .

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