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leaf extracts

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By Targets:	Akt (1) Apoptosis (1) Bacterial (3) Biochemical Assay Reagents (1) Caspase (1) COX (1) Drug Derivative (2) Drug Isomer (1) Drug Metabolite (1) ERK (1) Estrogen Receptor/ERR (1) Fungal (2) Glycosidase (2) JNK (1) mTOR (1) NF-κB (1) NO Synthase (1) Phytohormone (1) PI3K (1)
By Research Areas:	Endocrinology (1) Infection (7) Inflammation/Immunology (5) Metabolic Disease (2)

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Biochemical Assay Reagents

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-136302

Karrikinolide	Phytohormone	Others
Karrikinolide is a plant-active compound. Karrikinolide can be extracted from smoke water (SW). Karrikinolide promotes total Cytokinin production. Plants treated with Karrikinolide exhibit superior growth in terms of rooting, leaf and bulb size, and fresh weight .

HY-N8574

1-Heptacosanol Heptacosan-1-ol	Biochemical Assay Reagents	Infection
1-Heptacosanol (Heptacosan-1-ol) is a long-chain fatty alcohol with antifungal, antibacterial (against Escherichia coli and Staphylococcus aureus), nematicidal, anticancer and antioxidant activities. 1-Heptacosanol can be isolated from leaf extracts of Ficus septica and Lecaniodiscus cupanioides. 1-Heptacosanol not only effectively resists pathogenic fungal infections, but also shows potential against pepper anthracnose in phytopathology. 1-Heptacosanol can be used in the research of fungal infections, cancer and oxidative stress-related diseases .

HY-W585952

Salicylic acid 2-O-β-D-glucoside SA-2-O-β-D-glucoside	Drug Metabolite	Infection
Salicylic acid 2-O-β-D-glucoside (SA-2-O-β-D-glucoside) is the glucose-conjugated product of Salicylic Acid (HY-B0167) in plants. Salicylic acid 2-O-β-D-glucoside belongs to an inactive storage form. Salicylic acid 2-O-β-D-glucoside can be used in studies of plant pathogen infection .

HY-N13248

Mulberry Leaf Extract	Glycosidase	Metabolic Disease
Mulberry Leaf Extract is a mulberry leaf extract, and its components include: 1-Deoxynojirimycin. Mulberry Leaf Extract can effectively alleviate the adverse effects of high-fat diet on blood lipids and renal function, regulate lipid metabolism abnormalities, and significantly inhibit the accumulation of glycosylated substances in glomeruli. Mulberry Leaf Extract can regulate the key signaling pathways of diabetic nephropathy, but does not directly affect blood glucose levels. .

HY-N10133

Licoflavanone 3′-Prenylnaringenin	Bacterial mTOR Akt PI3K NF-κB Caspase JNK ERK COX NO Synthase Apoptosis	Others
Licoflavanone (3′-Prenylnaringenin) is a flavanone with antioxidant, anti-inflammatory and anticancer activities. Licoflavanone can be isolated from the leaf extract of Glycyrrhiza glabra. Licoflavanone downregulates the mTOR/PI3K/AKT signaling pathway to inhibit the proliferation, migration and invasion of cancer cells, while activates Bax, Bad and multiple caspase enzymes to induce apoptosis. Its anti-inflammatory effect is manifested by reducing the nuclear translocation of NF-κB, decreasing the phosphorylation levels of p38, JNK and ERK1/2, thereby inhibiting the expression of nitric oxide, proinflammatory cytokines, COX-2 and iNOS. Licoflavanone is used in studies on nasopharyngeal carcinoma and related mechanisms .

HY-123025

Schizozygine	Fungal	Inflammation/Immunology
Schizozygine is an alkaloid that can be isolated from Schizozygia caffaeoides. Schizozygia caffaeoides has been used as a traditional medicine for skin disease. The leaf extracts has high antifungal and antimicrobial activity .

HY-N1251

Scholaricine	Others	Others
Scholaricine (compound 13 ) is an alkaloid isolated from the leaf and stem-bark extracts of Alstonia spatulata. Scholaricine reverse multidrug resistance in vincristine-resistant KB cells with an IC₅₀ value of 13.35 μM .

HY-N1875

4-(Ethoxymethyl)phenol p-Hydroxybenzyl Et ether	Estrogen Receptor/ERR	Inflammation/Immunology
4-(Ethoxymethyl)phenol (p-Hydroxybenzyl Et ether) is a potent antioxidant from Amburana cearensis leaf extract, with in vitro cytogenotoxic properties. Amburana cearensis leaves can be used foe the research of respiratory diseases and inflammations .

HY-N13222

Lotus Leaf Extract	Others	Others
Lotus Leaf Extract is the extract of Lotus Leaf, with content of 2% , 3% Nuciferine HPLC.

HY-N1670

2'',4''-Di-O-(Z-p-Coumaroyl)afzelin	Others	Others
2'',4''-Di-O-(Z-p-Coumaroyl)afzelin (compound 9) is a compound isolated from the leaf extract of Machilusphilippinense Merr. .

HY-N12028

Acacetin 7-O-glucuronide	Others	Others
Acacetin 7-O-glucuronide is a glucuronide isolated from the methanolic leaf extract of Acacetin. Acacetin 7-O-glucuronide has potential applications in the development of nutraceuticals and pharmaceutical formulations .

HY-N8604

Methyl 4-O-caffeoylquinate	Others	Inflammation/Immunology
Methyl 4-O-caffeoylquinate is an extract naturally derived from the leaf ofIlex paraguariensis. Methyl 4-O-caffeoylquinate has human neutrophilic elastase (HNE) inhibitory activity .

HY-N12030

Acacetin 7-O-β-D-glucuronopyranosyl-(1→2)[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside	Others	Others
Acacetin 7-O-β-D-glucuronopyranosyl-(1→2)[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside (compound 8) is a flavonoid glycoside that can be obtained from black locust (Leguminosae ) isolated from leaf extract .

HY-N18695

Olive leaf extract	Bacterial	Infection
Olive leaf extract is an extract from olive leaves that has broad-spectrum antibacterial activity.

HY-N18666

Rosmarinus officinalis leaf extract	Bacterial	Infection Inflammation/Immunology
Rosmarinus officinalis leaf extract, derived from the leaves of the rosemary plant, possesses antioxidant, anti-inflammatory, antibacterial, and cognitive-enhancing properties. Active ingredients in Rosmarinus officinalis leaf extract include rosmarinic acid, caryopsisic acid, caryopsisol, and flavonoids.

HY-N17361

Methylgerambullone	Drug Isomer	Endocrinology
Methylgerambullone is a constitutional isomer of Methylisogerambullone. Methylgerambullone can be isolated from the methanolic leaf extract of Glycosmis angustifolia. Methylgerambullone shows the relaxatory effect on guinea-pig isolated ileum precontracted with Acetylcholine .

HY-N18716

Senna leaf extract	Others	Others
Senna Leaf Extract is the main raw material of Cassia angustifolia Vahl. Its main active ingredients are Sennoside A and B, and contain rhein, aloe-emodin, chrysophanol and other anthraquinones Derivatives and other glycosides.

HY-N18654

Perilla ocymoides leaf extract	Others	Others
Perilla Ocymoides Leaf Extract is derived from the dry leaves of Perilla, a plant of the Lamiaceae. The main active ingredient is rosmarinic acid, which, as a phenolic acid compound, has a variety of biological activities. It can be used as cosmetics material.

HY-N19683

Kaempferol-3-O-a-L-(3'',4''-di-Z-p-coumaroyl)-rhamnopyranoside	Glycosidase	Metabolic Disease
Kaempferol-3-O-a-L-(3'',4''-di-Z-p-coumaroyl)-rhamnopyranoside is a 3-O-(coumaroyl-rhamnopyranosyl)-flavonol compound found in the leaf extract of Machilus philippinense Merr. .

HY-N16683

Galangin 5-methyl ether	Others	Inflammation/Immunology
Galangin 5-methyl ether is a potentially active compound that can be naturally extracted from propolis. Propolis is a resinous substance collected by bees from the leaf buds and bark cracks of various trees, enriched with saliva and enzyme secretions. The propolis extract containing Galangin 5-methyl ether has pharmacological activities such as antibacterial, antiviral, and anti-inflammatory effects, and can be used in research related to cold syndromes, skin diseases, and oral inflammation .

HY-N19785

11,12-Dimethyl chebulate	Fungal	Infection
11,12-Dimethyl chebulate is a phenolic acid chebulate derivative that can be found in Acer saccharum fall leaves and Terminalia dhofarica leaf extracts. 11,12-Dimethyl exhibits antifungal activity and DPPH scavenging activity.11,12-Dimethyl chebulate can be used for the research of fungal infection .

HY-N19843

α-Thujenal	Drug Derivative	Others
α-Thujenal is a derivative of Thujene that can be isolated from the leaves of Laurus nobilis L. .

HY-N0055A

trans-Chlorogenic acid trans-3-O-Caffeoylquinic acid; trans-Heriguard; trans-NSC-407296	Drug Derivative	Infection
trans-Chlorogenic acid (trans-3-O-Caffeoylquinic acid) is a caffeoyl ester derivative of quinic acid, as well as an oviposition stimulant. trans-Chlorogenic acid can be found in the leaves of carrot (Daucus carota) and wild parsnip (Pastinaca sativa) .

HY-141717

α-cis-Bergamotene	Others	Infection
α-cis-Bergamotene is a sesquiterpene compound. α-cis-Bergamotene exhibits no antennal activity .

Cat. No.	Product Name	Type

HY-N8574

1-Heptacosanol Heptacosan-1-ol	Biochemical Assay Reagents
1-Heptacosanol (Heptacosan-1-ol) is a long-chain fatty alcohol with antifungal, antibacterial (against Escherichia coli and Staphylococcus aureus), nematicidal, anticancer and antioxidant activities. 1-Heptacosanol can be isolated from leaf extracts of Ficus septica and Lecaniodiscus cupanioides. 1-Heptacosanol not only effectively resists pathogenic fungal infections, but also shows potential against pepper anthracnose in phytopathology. 1-Heptacosanol can be used in the research of fungal infections, cancer and oxidative stress-related diseases .

1-Heptacosanol

Heptacosan-1-ol

Biochemical Assay Reagents

1-Heptacosanol (Heptacosan-1-ol) is a long-chain fatty alcohol with antifungal, antibacterial (against Escherichia coli and Staphylococcus aureus), nematicidal, anticancer and antioxidant activities. 1-Heptacosanol can be isolated from leaf extracts of Ficus septica and Lecaniodiscus cupanioides. 1-Heptacosanol not only effectively resists pathogenic fungal infections, but also shows potential against pepper anthracnose in phytopathology. 1-Heptacosanol can be used in the research of fungal infections, cancer and oxidative stress-related diseases .

Licoflavanone 3′-Prenylnaringenin	Structural Classification Glycyrrhiza glabra Linn. Flavonoids Leguminosae Flavonones Plants Source Classification	Bacterial mTOR Akt PI3K NF-κB Caspase JNK ERK COX NO Synthase Apoptosis
Licoflavanone (3′-Prenylnaringenin) is a flavanone with antioxidant, anti-inflammatory and anticancer activities. Licoflavanone can be isolated from the leaf extract of Glycyrrhiza glabra. Licoflavanone downregulates the mTOR/PI3K/AKT signaling pathway to inhibit the proliferation, migration and invasion of cancer cells, while activates Bax, Bad and multiple caspase enzymes to induce apoptosis. Its anti-inflammatory effect is manifested by reducing the nuclear translocation of NF-κB, decreasing the phosphorylation levels of p38, JNK and ERK1/2, thereby inhibiting the expression of nitric oxide, proinflammatory cytokines, COX-2 and iNOS. Licoflavanone is used in studies on nasopharyngeal carcinoma and related mechanisms .

Schizozygine	Apocynaceae Structural Classification Alkaloids Schizozygia coffeoides Baill. Other Alkaloids Plants Source Classification	Fungal
Schizozygine is an alkaloid that can be isolated from Schizozygia caffaeoides. Schizozygia caffaeoides has been used as a traditional medicine for skin disease. The leaf extracts has high antifungal and antimicrobial activity .

Scholaricine	Apocynaceae Alkaloids Alstonia spatulata Blume Other Alkaloids Plants Source Classification	Others
Scholaricine (compound 13 ) is an alkaloid isolated from the leaf and stem-bark extracts of Alstonia spatulata. Scholaricine reverse multidrug resistance in vincristine-resistant KB cells with an IC₅₀ value of 13.35 μM .

Acacetin 7-O-glucuronide	Flavonoids Flavones Labiatae Plants Vernonia Schreb. Source Classification	Others
Acacetin 7-O-glucuronide is a glucuronide isolated from the methanolic leaf extract of Acacetin. Acacetin 7-O-glucuronide has potential applications in the development of nutraceuticals and pharmaceutical formulations .

Methyl 4-O-caffeoylquinate	Aquifoliaceae Phenols Polyphenols Plants Tabernaemontana pandacaqui Lam. Source Classification	Others
Methyl 4-O-caffeoylquinate is an extract naturally derived from the leaf ofIlex paraguariensis. Methyl 4-O-caffeoylquinate has human neutrophilic elastase (HNE) inhibitory activity .

Acacetin 7-O-β-D-glucuronopyranosyl-(1→2)[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside	Flavonoids Flavones Leguminosae Robinia pseudoacacia Linn. Plants Source Classification	Others
Acacetin 7-O-β-D-glucuronopyranosyl-(1→2)[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside (compound 8) is a flavonoid glycoside that can be obtained from black locust (Leguminosae ) isolated from leaf extract .

Olive leaf extract	Structural Classification Extract	Bacterial
Olive leaf extract is an extract from olive leaves that has broad-spectrum antibacterial activity.

Rosmarinus officinalis leaf extract	Structural Classification Extract	Bacterial
Rosmarinus officinalis leaf extract, derived from the leaves of the rosemary plant, possesses antioxidant, anti-inflammatory, antibacterial, and cognitive-enhancing properties. Active ingredients in Rosmarinus officinalis leaf extract include rosmarinic acid, caryopsisic acid, caryopsisol, and flavonoids.

Methylgerambullone	Structural Classification Natural Products Rutaceae Plants Glycosmis angustifolia Lindl. ex Wight & Arn. Source Classification	Drug Isomer
Methylgerambullone is a constitutional isomer of Methylisogerambullone. Methylgerambullone can be isolated from the methanolic leaf extract of Glycosmis angustifolia. Methylgerambullone shows the relaxatory effect on guinea-pig isolated ileum precontracted with Acetylcholine .

Senna leaf extract	Structural Classification Extract	Others
Senna Leaf Extract is the main raw material of Cassia angustifolia Vahl. Its main active ingredients are Sennoside A and B, and contain rhein, aloe-emodin, chrysophanol and other anthraquinones Derivatives and other glycosides.

Perilla ocymoides leaf extract	Structural Classification Extract	Others
Perilla Ocymoides Leaf Extract is derived from the dry leaves of Perilla, a plant of the Lamiaceae. The main active ingredient is rosmarinic acid, which, as a phenolic acid compound, has a variety of biological activities. It can be used as cosmetics material.

Kaempferol-3-O-a-L-(3'',4''-di-Z-p-coumaroyl)-rhamnopyranoside	Structural Classification Flavonoids Flavones Camphora philippinensis (Merr.) Y. Yang, Bing Liu & Zhi Yang Plants Lauraceae Source Classification	Glycosidase
Kaempferol-3-O-a-L-(3'',4''-di-Z-p-coumaroyl)-rhamnopyranoside is a 3-O-(coumaroyl-rhamnopyranosyl)-flavonol compound found in the leaf extract of Machilus philippinense Merr. .

Galangin 5-methyl ether	Structural Classification Flavonols Flavonoids Animals Source Classification	Others
Galangin 5-methyl ether is a potentially active compound that can be naturally extracted from propolis. Propolis is a resinous substance collected by bees from the leaf buds and bark cracks of various trees, enriched with saliva and enzyme secretions. The propolis extract containing Galangin 5-methyl ether has pharmacological activities such as antibacterial, antiviral, and anti-inflammatory effects, and can be used in research related to cold syndromes, skin diseases, and oral inflammation .

11,12-Dimethyl chebulate	Structural Classification Dipteronia dyeriana Henry Ketones, Aldehydes, Acids Sapindaceae Plants Source Classification	Fungal
11,12-Dimethyl chebulate is a phenolic acid chebulate derivative that can be found in Acer saccharum fall leaves and Terminalia dhofarica leaf extracts. 11,12-Dimethyl exhibits antifungal activity and DPPH scavenging activity.11,12-Dimethyl chebulate can be used for the research of fungal infection .

α-Thujenal	Structural Classification Other Monoterpenes Terpenoids Plants Compositae Artemisia persica Boiss. Source Classification	Drug Derivative
α-Thujenal is a derivative of Thujene that can be isolated from the leaves of Laurus nobilis L. .

trans-Chlorogenic acid trans-3-O-Caffeoylquinic acid; trans-Heriguard; trans-NSC-407296	Structural Classification Hypericum perforatum Linn. Ketones, Aldehydes, Acids Guttiferae Plants Source Classification	Drug Derivative
trans-Chlorogenic acid (trans-3-O-Caffeoylquinic acid) is a caffeoyl ester derivative of quinic acid, as well as an oviposition stimulant. trans-Chlorogenic acid can be found in the leaves of carrot (Daucus carota) and wild parsnip (Pastinaca sativa) .

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leaf extracts

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Natural
Products