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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
38 Results for "
mammalian cell lines
" in MedChemExpress (MCE) Product Catalog:
Products (38)
38 Results for "mammalian cell lines" in MCE Product Catalog:
51
51 Cited Publications
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OSMI-1 is a cell-permeable O-GlcNAc transferase (OGT) inhibitor with an IC50 value of 2.7 μM. OSMI-1 inhibits protein O-linked N-acetylglucosamine (O-GlcNAcylation) in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans .
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12 Cited Publications
Cat. No.: HY-K3001
DMEM (Dulbecco's Modified Eagle Medium) is a widely used basal medium for supporting the growth of many different mammalian cells. Cell lines successfully cultured in DMEM include Hela, 293, Cos-7, and PC-12, as well as primary fibroblasts, neurons, glial cells, HUVECs, and smooth muscle cells. The 500 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
Cat. No.: HY-108692
CAS No.: 78473-71-9
Category:
Human Gut Microbiota Metabolites Microorganisms Lignans Phenylpropanoids Endogenous metabolite Disease Research Fields Cancer
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Cat. No.: HY-N7053
CAS No.: 936691-46-2
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Cat. No.: HY-110172
CAS No.: 1461648-55-4
PDI-IN-1 is a cell-permeable PDI covalent inhibitor with an IC50 of 1.7 μM against bovine PDI. PDI-IN-1 specifically modifies the Cys397 residue at the active site of human PDI, selectively labels endogenous PDI in living mammalian cancer cells, and effectively inhibits PDI-mediated insulin aggregation in vitro. PDI-IN-1 exhibits significant anti-tumor activity and inhibits the growth of various cancer cell lines .
Cat. No.: HY-P3840
CAS No.: 79943-68-3
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Cat. No.: HY-N2348
CAS No.: 309935-57-7
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(Rac)-OSMI-1 is the racemate of OSMI-1. OSMI-1 is a cell-permeable O-GlcNAc transferase (OGT) inhibitor with an IC50 value of 2.7 μM. OSMI-1 inhibits protein O-linked N-acetylglucosamine (O-GlcNAcylation) in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans .
Cat. No.: HY-108692R
CAS No.: 78473-71-9
Cat. No.: HY-N2347
CAS No.: 205304-88-7
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Cat. No.: HY-N7050
CAS No.: 799822-08-5
Category:
Microorganisms Monophenols Ketones, Aldehydes, Acids Phenols Disease Research Fields Cancer
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Cat. No.: HY-N7052
CAS No.: 799822-10-9
Category:
Microorganisms Monophenols Ketones, Aldehydes, Acids Phenols Disease Research Fields Cancer
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Cat. No.: HY-N10184
CAS No.: 540770-33-0
Synonyms: FKI-0550
Cat. No.: HY-W014004
CAS No.: 174664-65-4
Synonyms: CBHA
m-Carboxycinnamic acid bishydroxamide (CBHA) is a histone deacetylase inhibitor. m-Carboxycinnamic acid bishydroxamide modulates histone acetylation sites, alters DNA methylation and epigenetic status, increases global histone acetylation, alleviates transcription repression, and facilitates chromatin remodelling. m-Carboxycinnamic acid bishydroxamide can be used for the research of cloned embryo development and epigenetic regulation .
Cat. No.: HY-101071
CAS No.: 254753-54-3
Synonyms: (+)-Monastrol
(S)-Monastrol ((+)-Monastrol) is an allosteric inhibitor of the mitotic kinesin Eg5 that exhibits an antiproliferative effect against several cancer cell lines. (S)-Monastrol arrests mammalian cells in mitosis with monopolar spindles .
Cat. No.: HY-N2346
CAS No.: 309935-58-8
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Cat. No.: HY-N7049
CAS No.: 368870-67-1
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Cat. No.: HY-N7051
CAS No.: 799822-09-6
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Cat. No.: HY-172264
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XT17 is an anthrone compound with broad-spectrum antibacterial activity. It exerts its antibacterial effect by disrupting the cell wall and inhibiting DNA synthesis. XT17 exhibits weak hemolytic activity, low cytotoxicity against mammalian cell lines, and a low frequency of drug resistance. Meanwhile, XT17 shows in vivo efficacy in a mouse corneal infection model induced by Staphylococcus aureus or Pseudomonas aeruginosa. Further docking studies have confirmed that XT17 can form a stable complex with bacterial gyrase. XT17 can be used in the research of the anti - infection field .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
