238 Results for "

mannose

" in MedChemExpress (MCE) Product Catalog:
Products (238)

238 Results for "mannose" in MCE Product Catalog:

16
16 Publications Verification
Cat. No.: HY-19332
CAS No.: 109944-15-2
Synonyms: FR-900494
Kifunensine, a potent and selective inhibitor of class I α-mannosidases isolated from Actinomycete, prevents α-mannosidases I from trimming mannose residues on glycoproteins. Kifunensine inhibits ERAD .
loading...
    loading...
5
5 Cited Publications
Cat. No.: HY-N0379
CAS No.: 3458-28-4
D-Mannose is a C-2 superpolymer of glucose that occurs naturally in many plants and fruits. D-Mannose has anti-inflammatory and antitumor activity. D-Mannose plays an important role in immune regulation .
loading...
    loading...
5
5 Cited Publications
Cat. No.: HY-P2149
CAS No.: 11028-71-0
Concanavalin A can be coupled to agarose to form Concanavalin A (agarose) (HY-P2149A). Concanavalin A (ConA) is a selective, competitive binding agent that targets specific carbohydrate structures containing glucose and mannose; it acts as a mitogen and exhibits varying degrees of cytotoxicity, hepatotoxicity, and teratogenicity. Concanavalin A is also utilized for in vivo blood glucose monitoring in the context of diabetes .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P81214
Synonyms: mannose Receptor; C-type lectin domain family 13 member D; CD 206; CD206; CD206 antigen; CLEC13D; CLEC13DL; Macrophage mannose receptor; mannose receptor C type 1; MMR; MRC 1; MRC-1; MRC1_HUMAN; Macrophage mannose receptor 1; MRC1L1; C-type lectin domain family 13 member D-like; Macrophage mannose receptor 1-like protein 1.

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Rat

loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-168374
CAS No.: 1829524-73-3
DSPE-PEG 2000-Mannose is a mannose-containing lipid. DSPE-PEG 2000-Mannose is used to prepare mannose-conjugated Liposome (Man-lipo) for siRNA delivery. Mannose-modified liposomes encapsulating IDO siRNA (Man-lipo-siIDO) preferentially knock down IDO expression in the draining lymph nodes and spleens of melanoma-bearing mice. Man-lipo-siIDO delays the onset time of melanoma and reduces tumor volume .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N0379R
CAS No.: 3458-28-4
D-Mannose (Standard) is the analytical standard of D-Mannose. This product is intended for research and analytical applications. D-Mannose is a C-2 superpolymer of glucose that occurs naturally in many plants and fruits. D-Mannose has anti-inflammatory and antitumor activity. D-Mannose plays an important role in immune regulation .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-138802
CAS No.: 1306638-12-9
Purity:  99.86%
ML089 is an orally active inhibitor of phosphomannose isomerase (PMI) and PHOSPHO1, with an IC50 value of 1.3 μM against human PMI and an IC50 value of 0.8 μM against PHOSPHO1. ML089 blocks the catabolism of mannose-6-phosphate, directs mannose-6-phosphate to participate in protein glycosylation, increases mannose incorporation into cellular proteins, and reduces tritiated water production from mannose-6-phosphate. ML089 inhibits PMI in living cells. ML089 can be used in research related to congenital disorder of glycosylation type Ia (CDG-Ia) .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P83714M
Synonyms: MMR; MR; MRC1; macrophage mannose receptor; mannose receptor

Host:  

Rat

Application:  

FC

Reactivity:  

Mouse

loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W021425
CAS No.: 5505-63-5
Synonyms: (2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride
D-Mannosamine ((2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal) hydrochloride is a six-carbon amino sugar and an amino derivative of D-mannose. D-Mannosamine hydrochloride can block mannose receptors .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P86350
Synonyms: MRC1; CLEC13D; CLEC13DL; MRC1L1; Macrophage mannose receptor 1; MMR; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; Macrophage mannose receptor 1-like protein 1; CD206

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N0913
CAS No.: 13382-86-0
Manninotriose is a natural functional trisaccharide composed of three mannose molecules. Manninotriose binds to dihydrofolate reductase via hydrogen bond formation with Arg28. Manninotriose binds to thymidylate synthase via hydrogen bond formation with Arg50. Manninotriose acts as a membrane protectant and helps improve stress tolerance. Manninotriose can be used in research related to acute lymphoblastic leukemia .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W145667
CAS No.: 9036-88-8
Mannan is an orally active polysaccharide compound that binds to the mannose receptor (MR). Mannan promotes bacterial uptake and endosomal degradation by binding to MR, thereby enhancing the production of IL-12 in immune cells. Mannan enhances ROS production. Mannan modulates immunity, inhibits Aflatoxin B1 (HY-N6615)-induced toxicity, and reduces lipid .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W009783
CAS No.: 73465-43-7
1-Deoxymannojirimycin hydrochloride is a selective class I α1,2-mannosidase inhibitor with an IC50 of 20 μM. 1-Deoxymannojirimycin hydrochloride is also a N-linked glycosylation inhibitor. 1-Deoxymannojirimycin hydrochloride has antiviral activity against HIV‐1 strains . 1-Deoxymannojirimycin hydrochloride increases high mannose structures. 1-Deoxymannojirimycin hydrochloride can be used for the study of liver cancer and colon cancer .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W039897
CAS No.: 617-04-9
Synonyms: α-Methyl-D-mannoside
Research Areas:  

Infection

Methyl α-D-mannopyranoside (α-Methyl-D-mannoside) is a methyl glycoside derivative and conformational stabilizer of α-D-mannopyranose. The glycosidic bond conformation of Methyl α-D-mannopyranoside is significantly affected by the environment. In aqueous solution, Methyl α-D-mannopyranoside stabilizes into a trans conformation via intermolecular hydrogen bonds; in the gas phase, however, steric interactions drive Methyl α-D-mannopyranoside to prefer a clockwise gauche conformation. Methyl α-D-mannopyranoside also serves as a major component of secondary cell wall polymers in some bacteria and an active precursor site for virus-targeted glycoproteins. Methyl α-D-mannopyranoside acts as an acceptor substrate for alternansucrase, mediating the transfer of D-glucopyranosyl groups to generate a variety of glycosylated oligosaccharide products, with methyl α-D-glucopyranosyl-(1→6)-α-D-mannopyranoside as the main component. Methyl α-D-mannopyranoside is applicable to studies on bacterial pathogenic mechanisms associated with mannose-specific fimbrial lectins .
loading...
    loading...
Cat. No.: HY-19997
CAS No.: 92051-23-5
Synonyms: TATM
Mannose triflate is a glucose analog. Mannose triflate is a precursor for 18F-FDG synthesis for PET applications. Mannose triflate binds to 18F via SN2 nucleophilic substitution reaction. Mannose triflate can be used for an imaging technique in detection of cancer .
loading...
    loading...
Cat. No.: HY-W016508
CAS No.: 10030-80-5
Target:  

Drug Derivative

Research Areas:  

Metabolic Disease

L-Mannose is a monosaccharide and epimeric aldose. L-Mannose can be obtained via the reaction of L-arabinose with nitromethane derivatives. L-Mannose is applicable to research related to metabolism .
loading...
    loading...
Cat. No.: HY-N7389A
CAS No.: 103301-73-1
GDP-D-mannose disodium consists of GDP-α-D-mannose (HY-N7389B) and GDP-β-D-mannose. GDP-α-D-mannose serves as a donor substrate for mannosyltransferases and acts as a precursor of GDP-β-L-fucose. GDP-α-D-mannose exerts competitive inhibition on GTP (with a Ki value of 14.7 μM) and non-competitive inhibition on mannose-1-P (with a Ki value of 115 μM). GDP-D-mannose disodium is metabolized to GDP-L-fucose (HY-134433) via GMDS (Gmd) and TSTA3 (WcaG) .
loading...
    loading...
Cat. No.: HY-176879
Research Areas:  

Infection

NHS-PEG2000-Mannose is an NHS-PEG-Mannose containing PEG2000. NHS-PEG-Mannose is a D-mannose derivative and linker. NHS-PEG-Mannose can bind to phage coat proteins via amino-carboxyl reaction to form mannose-modified phage (Man-phage) .
loading...
    loading...
Cat. No.: HY-N0379S5
CAS No.: 70849-31-9
D-Mannose- 13C is the 13C labeled D-Mannose. D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific prote .
loading...
    loading...
Cat. No.: HY-16304
CAS No.: 27251-84-9
Mannose 1-phosphate is a phosphorylated mannose that serves as a precursor of GDP-mannose, a constituent unit of glycosylation biosynthetic pathways. Mannose 1-phosphate increases intracellular GDP-mannose concentration, promotes normalization of lipid-linked oligosaccharide structures, and enhances the formation of mature N-glycans on cellular proteins. Mannose 1-phosphate can be used in studies related to glycosylation disorders .
loading...
    loading...