314 Results for "

methylated polycyclic polyprenylated acylphloroglucinol

" in MedChemExpress (MCE) Product Catalog:
Products (314)

314 Results for "methylated polycyclic polyprenylated acylphloroglucinol" in MCE Product Catalog:

154
154 Publications Verification
Cat. No.: HY-13753
CAS No.: 18883-66-4
Purity:  99.20%
Synonyms: Streptozocin; NSC-85998; U 9889
Streptozotocin (Streptozocin; STZ) is an antibiotic widely used in experimental animal models of induced diabetes. Streptozotocin enters B cells via the glucose transporter (GLUT2) and causes the alkylation of DNA ( DNA-methylating ). Streptozotocin can induce the apoptosis of β cells .
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11
11 Cited Publications
Cat. No.: HY-N0297
CAS No.: 2306-27-6
Synonyms: Pedalitin permethyl ether
Sinensetin is a methylated flavonoid found in fruits that has strong anti-vascular and anti-inflammatory properties.
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11
11 Cited Publications
Cat. No.: HY-19313
CAS No.: 1793053-37-8
Research Areas:  

Cancer

LLY-507 is a potent and selective inhibitor of protein-lysine methyltransferase SMYD2. LLY-507 potently inhibits the ability of SMYD2 to methylate p53 peptide with an IC50 <15 nM. LLY-507 serves as a valuable chemical probe to aid in the dissection of SMYD2 function in cancer and other biological processes .
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9
9 Cited Publications
Cat. No.: HY-19340
CAS No.: 24144-92-1
Synonyms: (E)-2,3',4,5'-tetramethoxystilbene
Target:  

Cytochrome P450

Research Areas:  

Cancer

TMS ((E)-2,3',4,5'-tetramethoxystilbene) is a selective and competitive CYP1B1 inhibitor with an IC50 of 6 nM and a Ki value of 3 nM. TMS shows a lesser extent inhibitory effect on CYP1A1 (IC50=300 nM) and CYP1A2 (IC50=3.1 μM). TMS is a methylated derivative of resveratrol and has anti-cancer activity .
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8
8 Cited Publications
Cat. No.: HY-N6693
CAS No.: 2001-95-8
Synonyms: NSC 122023
Valinomycin is a potassium-specific ionophore, the valinomycin-K + complex can be incorporated into biological bilayer membranes with the hydrophobic surface of valinomycin, destroys the normal K + gradient across the membrane, and as a result kills the cells, incorporating into liposomes can significantly reduces the cytotoxicity and enhances the targeting effect. Valinomycin exhibits antibiotic, antifungal, antiviral, antitumor and insecticidal efficacy, thus can be used for relevant research .
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6
6 Cited Publications
Cat. No.: HY-N0823
CAS No.: 28831-65-4
Synonyms: (+)-Lithospermic acid
Lithospermic acid ((+)-Lithospermic acid) is a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, and has the anti-oxidative and hepatoprotective activity on carbon tetrachloride (CCl4)-induced acute liver damage in vitro and in vivo .
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5
5 Cited Publications
Cat. No.: HY-N2597
CAS No.: 552-59-0
Prunetin, an O-methylated isoflavone, possesses anti-inflammatory activity. Prunetin is a potent human aldehyde dehydrogenases inhibitor .
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5
5 Cited Publications
Cat. No.: HY-113354
CAS No.: 584-85-0
Purity:  99.85%
Anserine, a methylated form of Carnosine, is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine has blood-brain barrier permeability, and improves memory functions in Alzheimer's disease (AD)-model mice .
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4
4 Cited Publications
Cat. No.: HY-W011845
CAS No.: 57-97-6
Synonyms: 7,12-DMBA; 7,12-Dimethylbenzanthracene
Research Areas:  

Cancer

DMBA has carcinogenic activity as a polycyclic aromatic hydrocarbon (PAH). DMBA is used to induce tumor formation in various rodent models .
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4
4 Cited Publications
Cat. No.: HY-113137
CAS No.: 2140-67-2
Purity:  99.40%
N2,N2-Dimethylguanosine is a methylated modified nucleoside present in RNA and serves as a structural modification component of tRNA. N2,N2-Dimethylguanosine inhibits reverse transcriptase-mediated cDNA synthesis and is one of the key modifications affecting sequencing efficiency in high-throughput RNA sequencing. N2,N2-Dimethylguanosine can be selectively demethylated at one methyl group by AlkB mutant enzymes (such as D135S/L118V) and converted to N2-methylguanosine, thereby reducing the inhibition of reverse transcription .
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3
3 Cited Publications
Cat. No.: HY-113136
CAS No.: 2140-65-0
Purity:  98.39%
Synonyms: N1-Methylguanosine
1-Methylguanosine (N1-Methylguanosine) is a methylated nucleoside originating from RNA degradation. 1-Methylguanosine is a tumour marker .
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2
2 Cited Publications
Cat. No.: HY-W127705
CAS No.: 4213-45-0
Quinacrine mustard dihydrochloride is a fluorochrome. Quinacrine mustard dihydrochloride as a polycyclic aromatic agent can be used as mutagenic agent induces the mutants of bacteria. Quinacrine mustard dihydrochloride induces cell cycle arrest at G2/M-phase. Quinacrine mustard dihydrochloride has the potential for the research of plant, animal, or human chromosomes .
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2
2 Cited Publications
Cat. No.: HY-137977
CAS No.: 134029-62-2
Purity:  99.74%
Target:  

ERK Apoptosis

Research Areas:  

Cancer

DMU-212 is a methylated derivative of Resveratrol (HY-16561), with antimitotic, anti-proliferative, antioxidant and apoptosis promoting activities. DMU-212 induces mitotic arrest via induction of apoptosis and activation of ERK1/2 protein. DMU-212 has orally active .
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2
2 Cited Publications
Cat. No.: HY-W011552R
CAS No.: 2140-79-6
2'-O-Methyladenosine (Standard) is the analytical standard of 2'-O-Methyladenosine. This product is intended for research and analytical applications. 2'-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyladenosine exhibits unique hypotensive activities .
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2
2 Cited Publications
Cat. No.: HY-131031
CAS No.: 315702-75-1
Purity:  99.95%
Research Areas:  

Neurological Disease Cancer

KCC-07 is a potent and brain-penetrant MBD2 (methyl-CpG-binding domain protein 2) inhibitor. KCC-07 prevents binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1) inducing anti-proliferative BAI1/p53/p21 signaling . KCC-07 is a TRACER (transcriptional regulation via active control of epigenetic reprogramming) that can stimulate ER transcriptional activity . KCC-07 can be used for the stduy of breast cancer .
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1
1 Cited Publications
Cat. No.: HY-134124
CAS No.: 92614-59-0
Purity:  95.8%
Research Areas:  

Metabolic Disease

Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .
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1
1 Cited Publications
Cat. No.: HY-B1727
CAS No.: 85-01-8
Phenanthrene is an orally active polycyclic aromatic hydrocarbon (PAH) that induces inflammation, oxidative stress, and apoptosis. Additionally, phenanthrene is commonly used to detect or assess PAH pollution in the environment .
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1
1 Cited Publications
Cat. No.: HY-121107
CAS No.: 218-01-9
Purity:  99.74%
Chrysene is a high molecular weight (HMW), polycyclic aromatic hydrocarbon (PAH) known for its recalcitrance and carcinogenic properties .
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1
1 Cited Publications
Cat. No.: HY-W013570
CAS No.: 208-96-8
Acenaphthylene is a polycyclic aromatic hydrocarbon (PAH). PAHs are derived naturally from coal and tar deposits, and produced by incomplete combustion of organic matter .
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1
1 Cited Publications
Cat. No.: HY-W008794
CAS No.: 1011-74-1
Synonyms: (±)-Normetanephrine hydrochloride; DL-Normetanephrine hydrochloride; (Rac)-Normetanephrine hydrochloride
Normetanephrine ((±)-Normetanephrine) hydrochloride is the O-methylated metabolite of norepinephrine (NE) .
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