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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2365 Results for "
nucleophilic arylboronic acid coupling partner
" in MedChemExpress (MCE) Product Catalog:
Products (2365)
2365 Results for "nucleophilic arylboronic acid coupling partner" in MCE Product Catalog:
53
53 Publications Verification
Cat. No.: HY-B0445A
CAS No.: 20111-18-6
Synonyms: β-DPN sodium; β-NAD sodium; β-Nicotinamide Adenine Dinucleotide sodium
43
43 Cited Publications
Cat. No.: HY-P0014
CAS No.: 204656-20-2
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Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
43
43 Cited Publications
Cat. No.: HY-P0014B
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18
13
13 Cited Publications
Cat. No.: HY-W016319
CAS No.: 138-15-8
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12
12 Cited Publications
Synonyms: MC-207,110 dihydrochloride; Phe-Arg-β-naphthylamide dihydrochloride
10
10 Cited Publications
Cat. No.: HY-N0473A
CAS No.: 69847-45-6
Target:
8
8 Cited Publications
Synonyms: Maleimidocaproyl monomethylauristatin F
Research Areas:
McMMAF (Maleimidocaproyl monomethylauristatin F) is a drug-linker conjugate for ADCs, formed by coupling the potent microtubule inhibitor Monomethyl auristatin F (MMAF) (HY-15579) with a maleimidocaproyl (mc) linker. McMMAF can be conjugated with anti-BCMA antibodies to form J6M0-mcMMAF, promoting apoptosis and inhibiting tumor growth .
7
eCF506 (NXP900) is a highly potent and orally active YES1/SRC kinase inhibitor with an IC50 of 0.47 nM. eCF506 locks its target into its native “closed” conformation, thereby inhibiting both kinase activity and complex formation with protein partners. eCF506 can be used for the study of esophageal squamous cancer and breast cancer .
7
7 Cited Publications
Synonyms: 2-(Phosphonomethyl)pentanedioic acid
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Research Areas:
2-PMPA (2-(Phosphonomethyl)pentanedioic acid) is a glutamate carboxypeptidase II (GCPII) inhibitor with an IC50 of 0.0003 μM. 2-PMPA shows low blood-brain barrier penetration. 2-PMPA sodium blocks the hydrolysis of NAAG, regulates glutamate levels in the brain and neurovascular coupling. 2-PMPA is applicable to the research of neurological diseases .
7
7 Cited Publications
Cat. No.: HY-100788C
CAS No.: 373645-42-2
Synonyms: 2-(Phosphonomethyl)pentanedioic acid sodium
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Research Areas:
2-PMPA (2-(Phosphonomethyl)pentanedioic acid) sodium is a glutamate carboxypeptidase II (GCPII) inhibitor with an IC50 of 0.0003 μM. 2-PMPA sodium shows low blood-brain barrier penetration. 2-PMPA sodium blocks the hydrolysis of NAAG, regulates glutamate levels in the brain and neurovascular coupling. 2-PMPA sodium is applicable to the research of neurological diseases .
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7 Cited Publications
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NF449 octasodium is a highly potent P2X1 receptor antagonist, with IC50s of 0.28, 0.69, and 120 nM for rP2X1, rP2X1+5, P2X2+3, respectively. NF449 octasodium is a Gsα-selective G Protein antagonist. NF449 octasodium suppresses the rate of GTP[γS] binding to Gsα-s, inhibits the stimulation of adenylyl cyclase activity, and blocks the coupling of β-adrenergic receptors to Gs .
7
7 Cited Publications
Cat. No.: HY-W011391A
CAS No.: 7300-59-6
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7
7 Cited Publications
Cat. No.: HY-W345421
CAS No.: 122864-94-2
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5
5 Cited Publications
Cat. No.: HY-W009203
CAS No.: 30925-07-6
5
5 Cited Publications
Cat. No.: HY-W142119
CAS No.: 2792-66-7
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4
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4
4 Cited Publications
Cat. No.: HY-W142162
CAS No.: 6027-02-7
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3
3 Cited Publications
Cat. No.: HY-P3462
CAS No.: 1415456-99-3
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3
3 Cited Publications
Cat. No.: HY-P3462A
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
