427 Results for "

pigmented

" in MedChemExpress (MCE) Product Catalog:
Products (427)

427 Results for "pigmented" in MCE Product Catalog:

  • Natural Products Recommended:
10
10 Publications Verification
Cat. No.: HY-N1992
CAS No.: 30462-35-2
Synonyms: TF-3; ZP10
Theaflavin 3,3'-digallate (TF-3) is a potent Zika virus (ZIKV) protease inhibitor with an IC50 of 2.3 μM. Theaflavin 3,3'-digallat directly binds to ZIKVpro (Kd=8.86 μM) and inhibits ZIKV replication. Theaflavin 3,3'-digallat inhibits the activity of gp41 and NS2B-3 protease and has antiviral activity against HSV and HIV-1 . Theaflavin 3,3'-digallate, the typical pigment in black tea, is a potent antitumor agent .
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9
9 Cited Publications
Cat. No.: HY-114153C
CAS No.: 1303420-67-8
Target:  

c-Fms

Research Areas:  

Neurological Disease

PLX5622 in AIN-76A Diet (1200 ppm) contains 1200 mg of PLX5622 (HY-114153) per Kg of AIN-76 diet and it can be used for microglia clearance. PLX5622 in AIN-76A Diet (1200 ppm) is ideal choose for microglia function research in healthy/diseased states. PLX5622 in AIN-76A Diet (1200 ppm) has been verified by MedChemExpress (MCE).The color of PLX5622 in AIN-76A Diet (1200 ppm) provided by MCE is blue. Meanwhile, MCE will provide an equal amount of PLX5622-Free AIN-76A Diet (no added pigments) as a complimentary offering, which is used for the control group.
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4
4 Cited Publications
Cat. No.: HY-N0428
CAS No.: 751-03-1
Obacunone is a highly oxidized triterpenoid limonoid isolated from citrus plants. Obacunone exerts its anticancer effects by inducing apoptosis. Obacunone also protects retinal pigment epithelial (RPE) cells from ultraviolet (UV) radiation (UVR)-induced oxidative damage .
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3
3 Cited Publications
Cat. No.: HY-100711
CAS No.: 82-89-3
Purity:  99.89%
Synonyms: Prodigiosine; NSC47147
Prodigiosin (Prodigiosine) is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin is a potent inhibitor of the Wnt/β-catenin pathway. Prodigiosin has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties .
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3
3 Cited Publications
Cat. No.: HY-100711A
CAS No.: 56144-17-3
Purity:  98.00%
Synonyms: Prodigiosine hydrochloride
Prodigiosin (Prodigiosine) hydrochloride is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin hydrochloride is a potent proapoptotic agent, and inhibits Wnt/β-catenin pathway. Prodigiosin hydrochloride has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties .
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3
3 Cited Publications
Cat. No.: HY-N10473
CAS No.: 957-86-8
Pulcherriminic acid is a cyclic dipeptide antimicrobial agent with high affinity for Fe 3+, found mainly in Bacillus and yeast. Pulcherriminic acid chelates iron ions through a non-enzymatic reaction to form the extracellular red pigment pulcherrimin, which competes for iron nutrition and thus achieves an antibacterial effect. Pulcherriminic acid has great applications in food, agriculture and medical industries .
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2
2 Cited Publications
Cat. No.: HY-D1025
CAS No.: 11016-15-2
Synonyms: C-PC
C-phycocyanin (C-PC) is a protein pigment which is also widely used as an excellent nutrient supplement for human beings.
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2
2 Cited Publications
Cat. No.: HY-B0911
CAS No.: 11006-34-1
Research Areas:  

Cardiovascular Disease Cancer

Chlorophyllin sodium copper salt is an orally active green pigment, antioxidant and antimutagenic agent. Chlorophyllin sodium copper salt promotes hematopoiesis and thrombopoiesis .
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2
2 Cited Publications
Cat. No.: HY-N6641
CAS No.: 21516-68-7
Monascin is a kind of azaphilonoid pigments extracted from Monascus pilosus-fermented rice (red-mold rice). Monascin also exhibits anti-tumor-initiating activity and anti-inflammatory activity with oral administration. Monascin inhibits the activation of NOR 1 (an NO donor). Monascin is a Nrf2 activator and PPARγ agonist .
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2
2 Cited Publications
Cat. No.: HY-134928A
CAS No.: 1821308-73-9
Purity:  ≥90.0%
Synonyms: A2E TFA; N-retinylidene-N-retinylethanolamine TFA
Research Areas:  

Cancer

Pyridinium bisretinoid A2E (A2E) TFA is a fluorophore that can be isolated from lipofuscin in the retinal pigment epithelium (RPE). Pyridinium bisretinoid A2E TFA is an initiator of blue-light-induced apoptosis. Photoactivation of Pyridinium bisretinoid A2E TFA mediates autophagy and the production of reactive oxygen species. Pyridinium bisretinoid A2E TFA can be used in the study of retinal degenerative diseases .
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2
2 Cited Publications
Cat. No.: HY-W040045
CAS No.: 18466-51-8
Synonyms: Pelargonidin-3-O-glucoside chloride
Callistephin (Pelargonidin 3-O-glucoside) chloride is an anthocyanin. Callistephin chloride regulates the expression of inflammatory (reducing iNOS/TNF-α/COX-2) and apoptosis-related proteins by inhibiting p38 phosphorylation, and enhances the protective effect of Isoflurane (HY-A0134) on microglial cell damage. Callistephin chloride significantly reduces ROS levels, eliminates DPPH free radicals, protects retinal pigment epithelial cells, and inhibits lipid peroxidation. Callistephin chloride can alleviate glutamate excitotoxicity, reduce neuronal apoptosis, and protect cerebellar granule neurons. Callistephin chloride can inhibit the proliferation and metastasis of breast cancer cells by inducing apoptosis .
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1
1 Cited Publications
Cat. No.: HY-113485
CAS No.: 8049-97-6
Purity:  ≥99.0%
Melanin is a unique pigment with myriad functions. It is multifunctional, providing defense against environmental stresses such as ultraviolet (UV) light, oxidizing agents and ionizing radiation.
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1
1 Cited Publications
Cat. No.: HY-16115
CAS No.: 157124-84-0
Target:  

Bacterial

Research Areas:  

Metabolic Disease

BPH-652 is a S. aureus dehydrosqualene synthase (CrtM) inhibitor, with a Ki of 1.5 nM and an IC50 of 100-300 nM (S. aureus pigment formation) .
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1
1 Cited Publications
Cat. No.: HY-N6643
CAS No.: 514-66-9
Rubropunctamine is a redMonascus pigment. Not only Rubropunctamine exerts antibiotic action against bacteria but also against some yeast and filamentous fungi strains. Rubropunctamine has potential embryotoxicity and teratogenicity .
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1
1 Cited Publications
Cat. No.: HY-135005
CAS No.: 856699-18-8
Purity:  99.3%
Biliverdin hydrochloride, a tetrapyrrolic pigment, is a product of heme catabolism. Heme is broken down into Biliverdin and carbon monoxide and iron by heme oxidase. Biliverdin hydrochloride is then quickly broken down to bilirubin by Biliverdin reductase. Biliverdin hydrochloride is anti-mutagenic, an antioxidant, anti-inflammatory, and immunosuppressant .
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1
1 Cited Publications
Cat. No.: HY-N7766
CAS No.: 514-67-0
Rubropunctatin, an orange azaphilone pigment, is isolated from the extracts of Monascus pilosus-fermented rice (red-mold rice). Rubropunctatin has anti-inflammatory, immunosuppressive and antioxidative effects, and also exhibits anti-tumor activity .
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1
1 Cited Publications
Cat. No.: HY-N1453
CAS No.: 123940-54-5
Hypocrellin B, a pigment isolated from the fungi Hypocrella bambusae and Shiraia bambusicola, is an apoptosis inducer. Hypocrellin B can be used as a photosensitizer for photodynamic therapy of cancer. Hypocrellin B also has antimicrobial and antileishmanial activities .
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1
1 Cited Publications
Cat. No.: HY-W009938
CAS No.: 90-44-8
Synonyms: Anthracen-9(10H)-one
Anthrone is an organic compound commonly used as a dye and intermediate. It can be used to make products such as pigments, dyes and fluorescent whitening agents, and is widely used in certain industrial production fields such as textile manufacturing, soap making and paper making. In addition, this compound is also used as a reagent and catalyst in some organic synthesis reactions.
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1
1 Cited Publications
Cat. No.: HY-135005A
CAS No.: 114-25-0
Purity:  ≥70.0%
Biliverdin, a tetrapyrrolic pigment, is a product of heme catabolism. Heme is broken down into Biliverdin and carbon monoxide and iron by heme oxidase. Biliverdin is then quickly broken down to bilirubin by Biliverdin reductase. Biliverdin can mediate the protective effects of HO-1 in many disease models including IRI and organ transplantation. Biliverdin exhibits anti-mutagenic, an antioxidant, anti-inflammatory, and immunosuppressant properties .
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1
1 Cited Publications
Cat. No.: HY-113283
CAS No.: 451-13-8
Purity:  99.46%
Homogentisic acid is an orally active, blood-brain barrier-permeable amyloidogenic compound that functions as both an amyloid component and a pigment precursor. Accumulation of homogentisic acid downregulates tight junction proteins (such as claudin-5, occludin, ZO-1) and impairs blood-brain barrier integrity. Homogentisic acid and its oxidation product benzoquinone acetic acid not only induce the aggregation and fibrosis of multiple proteins (such as Aβ1-42, α-synuclein, SAA, Transthyretin (TTR), atrial natriuretic peptide), but also trigger oxidative stress, damage to the Wnt/β-catenin pathway, and neurotoxicity, leading to ochronosis pigment deposition and synaptic dysfunction. At specific concentrations, homogentisic acid exerts no cytotoxicity or genotoxicity on human peripheral blood lymphocytes, and even counteracts the genotoxicity induced by Irinotecan (HY-16562). Homogentisic acid serves as an important tool molecule for investigating the mechanisms of diseases including ochronosis, secondary amyloidosis, Alzheimer's disease, and colorectal cancer .
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