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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
preadipocytes
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "preadipocytes" in MCE Product Catalog:
4
4 Cited Publications
Synonyms: Cichoric acid; Dicaffeoyltartaric acid
4
4 Cited Publications
Cat. No.: HY-N2593
CAS No.: 32507-66-7
4
4 Cited Publications
Cat. No.: HY-N0226A
CAS No.: 889665-86-5
3
2
2 Cited Publications
Cat. No.: HY-N1970
CAS No.: 31721-94-5
Target:
1
Category:
Human Gut Microbiota Metabolites Microorganisms Immune System Disorder Ketones, Aldehydes, Acids Disease markers Endogenous metabolite
Target:
1
1 Cited Publications
Target:
Research Areas:
PPARγ-IN-2 (Compound 5a) is a PPARγ inhibitor. PPARγ-IN-2 inhibits TG accumulation in 3T3-L1 preadipocytes (EC50: 0.106 μM). PPARγ-IN-2 inhibits high-cholesterol diet (HFC)-induced obesity and related metabolic syndrome, and reduces lipid accumulation in adipose tissue .
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Research Areas:
JTE-907 is a selective and orally active cannabinoid CB2 receptor inverse agonist and exerts anti-inflammatory effects. JTE-907 upregulates IL-6, MCP-1, IL-1β, VEGF, ANGPTL4, and TRPV1 in mature adipocytes. JTE-907 downregulates CB1, MCP-1, and IL-1β in preadipocytes. JTE-907 inhibits ear swelling in mice. JTE-907 reverses the protective effects of CB2 agonists and Anandamide (HY-10863) against cytokine-evoked colonic mucosal damage. JTE-907 can be used for the research of allergic dermatitis, obesity, and colitis .
Cat. No.: HY-W012722BS
CAS No.: 1795020-84-6
Synonyms: α-Ketoisocaproic acid-d7 sodium
Synonyms: Cichoric acid (Standard); Dicaffeoyltartaric acid (Standard)
Cat. No.: HY-N5072R
CAS No.: 17817-31-1
Synonyms: 4',6,7-Trihydroxyisoflavone (Standard)
Category:
Flavonoids Glycine max (L.) merr Phenols Polyphenols Leguminosae Extract Plants Isoflavones
Target:
Cat. No.: HY-N1970R
CAS No.: 31721-94-5
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Cat. No.: HY-A0241R
CAS No.: 112362-50-2
Synonyms: RP54476 (Standard)
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Research Areas:
Stearic acid (Standard) is the analytical standard of Stearic acid. This product is intended for research and analytical applications. Stearic acid is a long-chain dietary saturated fatty acid that can significantly reduce visceral fat by inducing apoptosis of preadipocytes. Stearic acid can be used in the study of cardiovascular and metabolic diseases .
Category:
Umbelliferae Extract Coumarins Melampodium divaricatum (Rich.) DC. Phenylpropanoids Plants
Target:
Cat. No.: HY-N11507
CAS No.: 2319668-87-4
Synonyms: TKV
Target:
Cat. No.: HY-N2593R
CAS No.: 32507-66-7
Cat. No.: HY-184061
CAS No.: 2590661-64-4
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Research Areas:
Carboxylesterase 2-IN-1 is a potent carboxylesterase CES2 inhibitor with an IC50 of 0.13 μM. Carboxylesterase 2-IN-1 blocks the hydrolysis of fluorescein diacetate by CES2 via non-competitive inhibition. Carboxylesterase 2-IN-1 also effectively inhibits adipogenesis induced in mouse preadipocytes .
Cat. No.: HY-118386
CAS No.: 1060478-12-7
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Research Areas:
H2-005 is a compound that selectively inhibits diacylglycerol acyltransferase 2 (DGAT2) and has the activity to inhibit triacylglycerol synthesis in hepatocytes and preadipocytes. H2-005 significantly reduces triacylglycerol biosynthesis in HepG2 hepatocytes and 3T3-L1 preadipocytes. H2-005 exhibits specific inhibitory activity in DGAT2-overexpressing HEK293 cells. H2-005 almost completely inhibits lipid droplet formation in 3T3-L1 cells when co-treated with a DGAT1 inhibitor. H2-005 will contribute to DGAT2-related lipid metabolism research and the development of drugs to inhibit metabolic diseases .
Cat. No.: HY-113922
CAS No.: 109229-57-4
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Research Areas:
Englitazone sodium is a thiazolidinedione compound. Englitazone sodium selectively activates PPARγ1 and PPARγ2. Englitazone sodium improves insulin sensitivity, induces adipogenesis in preadipocytes and mesenchymal stem cells, and inhibits the channel currents of Kir6.2-SUR1 and Kir6.2D26. Englitazone sodium is applicable to research related to non-insulin-dependent diabetes mellitus .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
